Variant report

Variant	rs10776612
Chromosome Location	chr10:49735563-49735564
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:1)
CpG islands
(count:0)
Chromatin interactive
region (count:6)
LncRNA
region (count:0)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:1 , 50 per page) page: 1

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	POLR2A	chr10:49732506-49735617	U87	brain:	n/a	n/a

No data

(count:6 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr10:49732450..49736073-chr10:49745484..49747337,3	K562	blood:
2	chr10:49723375..49726156-chr10:49734098..49735696,2	K562	blood:
3	chr10:49735319..49737955-chr10:49741189..49744071,3	K562	blood:
4	chr10:49728278..49730506-chr10:49735038..49737361,2	K562	blood:
5	chr10:49729006..49734314-chr10:49734624..49737361,4	K562	blood:
6	chr10:49677603..49679164-chr10:49733692..49735615,2	K562	blood:

No data

Variant related genes	Relation type
ARHGAP22	TF binding region
ENSG00000128805	Chromatin interaction

Extended variants
information (count: 30 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:25)

rs_ID	r²[population]
rs10776611	0.92[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.86[AFR][1000 genomes];0.98[AMR][1000 genomes];0.99[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs10776613	0.92[ASN][1000 genomes]
rs10857593	0.86[AFR][1000 genomes];0.98[AMR][1000 genomes];0.99[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs11101348	0.88[CHD][hapmap];0.90[JPT][hapmap]
rs11101349	0.88[CHD][hapmap];0.90[JPT][hapmap]
rs11101370	0.80[JPT][hapmap]
rs11101371	0.80[JPT][hapmap]
rs11101372	0.92[ASN][1000 genomes]
rs12763969	0.90[JPT][hapmap]
rs12768718	0.88[CHD][hapmap];0.90[JPT][hapmap]
rs2278676	0.90[CHD][hapmap];0.95[JPT][hapmap]
rs34223875	0.92[ASN][1000 genomes]
rs4012792	0.81[CHB][hapmap];0.95[JPT][hapmap];0.92[ASN][1000 genomes]
rs4838413	0.90[JPT][hapmap]
rs4838416	0.81[CEU][hapmap];0.90[CHB][hapmap];0.95[CHD][hapmap];0.95[GIH][hapmap];1.00[JPT][hapmap];0.90[ASN][1000 genomes]
rs4838608	0.88[CHD][hapmap];0.90[JPT][hapmap]
rs4838609	0.88[CHD][hapmap];0.90[JPT][hapmap]
rs4838613	0.92[ASN][1000 genomes]
rs4838616	0.81[CHB][hapmap];0.93[CHD][hapmap];0.95[JPT][hapmap];0.92[ASN][1000 genomes]
rs6537565	0.88[CHD][hapmap];0.90[JPT][hapmap]
rs7088885	0.92[ASN][1000 genomes]
rs7098760	0.88[CHD][hapmap];0.90[JPT][hapmap]
rs7896115	0.87[CHB][hapmap];0.93[CHD][hapmap];1.00[JPT][hapmap];0.92[ASN][1000 genomes]
rs7910327	0.90[CHD][hapmap];0.95[JPT][hapmap];0.80[ASN][1000 genomes]
rs7918009	0.92[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:5 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv895371	chr10:49492075-50232180	Weak transcription Active TSS Bivalent Enhancer Flanking Active TSS Enhancers Flanking Bivalent TSS/Enh Strong transcription Bivalent/Poised TSS Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	35 gene(s)	inside rSNPs	diseases
2	nsv895372	chr10:49576878-49933488	Enhancers Weak transcription Bivalent Enhancer Genic enhancers Strong transcription Flanking Bivalent TSS/Enh Flanking Active TSS Transcr. at gene 5' and 3' ZNF genes & repeats Active TSS Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	20 gene(s)	inside rSNPs	diseases
3	nsv467191	chr10:49669142-49735563	Enhancers Flanking Active TSS Active TSS Bivalent Enhancer Strong transcription Weak transcription Flanking Bivalent TSS/Enh Genic enhancers Bivalent/Poised TSS ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	11 gene(s)	inside rSNPs	diseases
4	nsv550813	chr10:49669142-49735563	Flanking Bivalent TSS/Enh Active TSS Weak transcription Genic enhancers Bivalent Enhancer Bivalent/Poised TSS Enhancers Flanking Active TSS Strong transcription ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	11 gene(s)	inside rSNPs	diseases
5	nsv550814	chr10:49705142-49735563	Weak transcription Enhancers Strong transcription Flanking Active TSS Genic enhancers Flanking Bivalent TSS/Enh Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats Active TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	9 gene(s)	inside rSNPs	diseases

Variant related diseases (count:1)

Disease	PMID	Source
Conduct disorder	20585324	GWAS catalog

Chromatin state (count:35 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:49732200-49750800	Weak transcription	Gastric	stomach
2	chr10:49732800-49736200	Enhancers	HUVEC	blood vessel
3	chr10:49732800-49736800	Weak transcription	Right Atrium	heart
4	chr10:49732800-49742000	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
5	chr10:49733800-49735600	Enhancers	Fetal Stomach	stomach
6	chr10:49733800-49736800	Enhancers	Brain Substantia Nigra	brain
7	chr10:49734000-49735800	Enhancers	Brain Inferior Temporal Lobe	brain
8	chr10:49734000-49736000	Enhancers	Brain Cingulate Gyrus	brain
9	chr10:49734200-49735600	Enhancers	Brain Angular Gyrus	brain
10	chr10:49734200-49736000	Enhancers	Brain Hippocampus Middle	brain
11	chr10:49734400-49743400	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
12	chr10:49734400-49762400	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
13	chr10:49734600-49736600	Enhancers	NHDF-Ad	bronchial
14	chr10:49734800-49735600	Enhancers	Fetal Kidney	kidney
15	chr10:49734800-49735800	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
16	chr10:49734800-49735800	Enhancers	Ovary	ovary
17	chr10:49734800-49741800	Weak transcription	Fetal Muscle Trunk	muscle
18	chr10:49734800-49743200	Weak transcription	HMEC	breast
19	chr10:49735000-49735600	Enhancers	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
20	chr10:49735000-49735600	Enhancers	IMR90 fetal lung fibroblasts Cell Line	lung
21	chr10:49735000-49735600	Bivalent Enhancer	Skeletal Muscle Male	skeletal muscle
22	chr10:49735200-49735600	Transcr. at gene 5' and 3'	Foreskin Fibroblast Primary Cells skin01	Skin
23	chr10:49735200-49735800	Enhancers	Ganglion Eminence derived primary cultured neurospheres	brain
24	chr10:49735200-49736000	Genic enhancers	HSMM	muscle
25	chr10:49735200-49736400	Enhancers	Osteobl	bone
26	chr10:49735400-49735600	Enhancers	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
27	chr10:49735400-49735600	Enhancers	Foreskin Fibroblast Primary Cells skin02	Skin
28	chr10:49735400-49735600	Enhancers	Pancreas	Pancrea
29	chr10:49735400-49735600	Enhancers	NH-A	brain
30	chr10:49735400-49736000	Enhancers	Muscle Satellite Cultured Cells	--
31	chr10:49735400-49736400	Enhancers	NHLF	lung
32	chr10:49735400-49742000	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
33	chr10:49735400-49742000	Weak transcription	Cortex derived primary cultured neurospheres	brain
34	chr10:49735400-49749400	Weak transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
35	chr10:49735400-49756800	Weak transcription	HSMMtube	muscle

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