Variant report

Variant	rs45563932
Chromosome Location	chr10:50374930-50374931
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr10:50374066..50375952-chr10:50506772..50508302,2	K562	blood:
2	chr10:50372843..50375654-chr10:50384413..50387038,2	MCF-7	breast:
3	chr10:50189169..50190058-chr10:50374196..50375038,2	K562	blood:

Variant related genes	Relation type
ENSG00000177354	Chromatin interaction
ENSG00000236208	Chromatin interaction
ENSG00000204161	Chromatin interaction

Extended variants
information (count: 40 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:38)

rs_ID	r²[population]
rs10508911	0.83[EUR][1000 genomes]
rs10857434	0.81[EUR][1000 genomes]
rs11100985	0.82[EUR][1000 genomes]
rs11100994	0.91[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs11814668	0.91[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs11815070	0.91[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs17011755	0.84[EUR][1000 genomes]
rs17011799	0.84[EUR][1000 genomes]
rs17773666	0.82[AMR][1000 genomes];0.85[EUR][1000 genomes]
rs17774010	0.86[AMR][1000 genomes]
rs17774028	0.82[AFR][1000 genomes];0.88[AMR][1000 genomes]
rs17774058	0.83[AMR][1000 genomes]
rs55648711	0.87[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs55872223	0.84[EUR][1000 genomes]
rs55936311	0.91[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs56081724	0.89[AFR][1000 genomes];0.90[AMR][1000 genomes]
rs56197478	0.84[EUR][1000 genomes]
rs59889308	0.80[EUR][1000 genomes]
rs61848377	0.80[EUR][1000 genomes]
rs61848380	0.81[EUR][1000 genomes]
rs7073558	0.89[AFR][1000 genomes];0.88[AMR][1000 genomes]
rs7073561	0.82[AFR][1000 genomes];0.88[AMR][1000 genomes]
rs72785044	0.82[AMR][1000 genomes];0.85[EUR][1000 genomes]
rs72785050	0.88[EUR][1000 genomes]
rs72785051	0.88[EUR][1000 genomes]
rs72785060	0.84[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs72785072	0.87[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs72785076	0.87[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs72785084	0.91[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs72785087	0.91[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs72786903	0.95[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs72789086	0.92[AFR][1000 genomes];0.98[AMR][1000 genomes];0.97[EUR][1000 genomes]
rs72789089	0.89[AFR][1000 genomes];0.90[AMR][1000 genomes]
rs72789095	0.82[AFR][1000 genomes];0.88[AMR][1000 genomes]
rs72789097	0.82[AFR][1000 genomes];0.88[AMR][1000 genomes]
rs7900761	0.89[AFR][1000 genomes];0.88[AMR][1000 genomes]
rs7905715	0.92[AFR][1000 genomes];0.98[AMR][1000 genomes];0.97[EUR][1000 genomes]
rs7919424	0.89[AFR][1000 genomes];0.90[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv895375	chr10:50306386-51028871	Weak transcription Active TSS Strong transcription Enhancers Flanking Active TSS Bivalent Enhancer Genic enhancers ZNF genes & repeats Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	33 gene(s)	inside rSNPs	diseases
2	nsv534410	chr10:50317458-50826916	Weak transcription Bivalent Enhancer Enhancers Active TSS Strong transcription Flanking Active TSS Bivalent/Poised TSS Genic enhancers ZNF genes & repeats Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	30 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs45563932	C10orf128	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:39 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:50359000-50382200	Weak transcription	Left Ventricle	heart
2	chr10:50359200-50375400	Weak transcription	Right Atrium	heart
3	chr10:50362400-50380600	Weak transcription	Brain Cingulate Gyrus	brain
4	chr10:50366200-50378200	Weak transcription	Stomach Smooth Muscle	stomach
5	chr10:50366800-50375400	Weak transcription	H1 Cell Line	embryonic stem cell
6	chr10:50367600-50376200	Strong transcription	Primary hematopoietic stem cells short term culture	blood
7	chr10:50367600-50384600	Weak transcription	Dnd41	blood
8	chr10:50368000-50375600	Weak transcription	Breast Myoepithelial Primary Cells	Breast
9	chr10:50368200-50380800	Weak transcription	Esophagus	oesophagus
10	chr10:50369000-50377200	Weak transcription	Brain Angular Gyrus	brain
11	chr10:50369600-50380400	Weak transcription	Gastric	stomach
12	chr10:50370000-50375000	Weak transcription	Brain Substantia Nigra	brain
13	chr10:50371600-50377200	Weak transcription	Primary B cells from cord blood	blood
14	chr10:50372000-50384000	Weak transcription	Colonic Mucosa	Colon
15	chr10:50372400-50377000	Weak transcription	IMR90 fetal lung fibroblasts Cell Line	lung
16	chr10:50372400-50377000	Weak transcription	NHDF-Ad	bronchial
17	chr10:50372800-50375600	Weak transcription	Skeletal Muscle Female	skeletal muscle
18	chr10:50372800-50376800	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
19	chr10:50372800-50377600	Weak transcription	Brain Hippocampus Middle	brain
20	chr10:50372800-50386200	Weak transcription	Pancreas	Pancrea
21	chr10:50373000-50375200	Weak transcription	Primary B cells from peripheral blood	blood
22	chr10:50373000-50376800	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
23	chr10:50373200-50375000	Strong transcription	Primary neutrophils fromperipheralblood	blood
24	chr10:50373200-50375600	Strong transcription	Adipose Nuclei	Adipose
25	chr10:50373200-50376400	Strong transcription	Primary Natural Killer cells fromperipheralblood	blood
26	chr10:50373200-50376400	Strong transcription	Duodenum Mucosa	Duodenum
27	chr10:50373200-50385200	Weak transcription	Colon Smooth Muscle	Colon
28	chr10:50373400-50376000	Strong transcription	Spleen	Spleen
29	chr10:50373600-50383000	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
30	chr10:50374000-50375200	Strong transcription	Skeletal Muscle Male	skeletal muscle
31	chr10:50374000-50375200	Flanking Active TSS	K562	blood
32	chr10:50374000-50375600	Strong transcription	Primary T helper 17 cells PMA-I stimulated	--
33	chr10:50374400-50376400	Enhancers	Fetal Muscle Leg	muscle
34	chr10:50374800-50375000	Enhancers	Brain Inferior Temporal Lobe	brain
35	chr10:50374800-50375000	Enhancers	Brain Dorsolateral Prefrontal Cortex	brain
36	chr10:50374800-50375400	ZNF genes & repeats	Lung	lung
37	chr10:50374800-50376000	Genic enhancers	Right Ventricle	heart
38	chr10:50374800-50377000	Weak transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
39	chr10:50374800-50379000	Weak transcription	Rectal Mucosa Donor 29	rectum

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