Variant report

Variant	rs7074806
Chromosome Location	chr10:43015560-43015561
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-ZNF33B-4	chr10:43008961-43016575	NONHSAT012887
2	lnc-ZNF33B-4	chr10:43015143-43016494	NONHSAT012890

Extended variants
information (count: 127 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:109)

rs_ID	r²[population]
rs10900240	0.81[EUR][1000 genomes]
rs11239612	0.93[ASN][1000 genomes]
rs11239616	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs11239617	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs11239618	0.83[AMR][1000 genomes];0.87[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11239619	0.81[EUR][1000 genomes]
rs11239621	0.81[EUR][1000 genomes]
rs11239622	0.81[EUR][1000 genomes]
rs11239639	0.93[AMR][1000 genomes];0.93[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs11239641	0.98[ASN][1000 genomes]
rs11239642	0.85[AMR][1000 genomes];0.93[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11239643	0.85[AMR][1000 genomes];0.93[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11239644	0.81[AFR][1000 genomes];0.93[AMR][1000 genomes];0.96[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11239647	0.99[ASN][1000 genomes]
rs11239648	0.99[ASN][1000 genomes]
rs11239651	0.96[AMR][1000 genomes];0.96[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11239653	0.89[AMR][1000 genomes];0.93[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11239661	1.00[AMR][1000 genomes];0.93[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs11239662	0.96[AMR][1000 genomes];0.93[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs11239663	0.92[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs11239664	0.93[ASN][1000 genomes]
rs11239668	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs11239669	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs11239670	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs11239671	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs11239672	0.89[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs11239675	0.91[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs11239682	0.85[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs1136118	0.80[AFR][1000 genomes];0.93[AMR][1000 genomes];0.93[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs11528468	0.83[AMR][1000 genomes];0.87[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs11528472	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs11528550	0.91[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs11528552	0.96[AMR][1000 genomes];0.93[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs11528554	0.93[ASN][1000 genomes]
rs12217930	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs12218051	0.85[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs12218403	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs12218419	0.89[AMR][1000 genomes];0.93[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs12219232	0.81[AFR][1000 genomes];0.96[AMR][1000 genomes];0.96[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12219443	1.00[ASN][1000 genomes]
rs12219669	0.93[ASN][1000 genomes]
rs12221072	0.85[AMR][1000 genomes];0.93[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12221408	0.94[AMR][1000 genomes];0.88[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs12257762	0.81[EUR][1000 genomes]
rs12257897	0.81[EUR][1000 genomes]
rs12259767	0.81[EUR][1000 genomes]
rs12263651	0.81[EUR][1000 genomes]
rs12268359	0.81[EUR][1000 genomes]
rs12771775	0.82[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs17157474	0.86[EUR][1000 genomes]
rs1831910	0.87[AMR][1000 genomes];0.87[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs1831916	0.81[AFR][1000 genomes];0.93[AMR][1000 genomes];0.96[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs1855448	0.85[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs1855449	0.85[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs1855451	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs2005977	0.91[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs2005978	0.91[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs2016696	0.80[AMR][1000 genomes];0.81[EUR][1000 genomes]
rs210239	0.80[ASN][1000 genomes]
rs210254	0.80[ASN][1000 genomes]
rs3740324	0.82[AMR][1000 genomes];0.81[EUR][1000 genomes]
rs3740325	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs3740327	0.82[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs3740328	0.85[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs3758512	0.89[AMR][1000 genomes];0.93[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs3758513	0.96[AMR][1000 genomes];0.96[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4262680	0.86[EUR][1000 genomes]
rs6593371	0.96[AMR][1000 genomes];0.93[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs66635049	0.86[EUR][1000 genomes]
rs7068874	0.81[AFR][1000 genomes];0.96[AMR][1000 genomes];0.96[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs7069467	0.84[EUR][1000 genomes]
rs7069663	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs7071990	0.89[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs7072559	0.90[ASN][1000 genomes]
rs7075245	0.91[AMR][1000 genomes];0.87[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs7076170	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs7076534	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs7076624	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs7076787	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs7078390	0.89[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs7079577	0.86[EUR][1000 genomes]
rs7079581	0.82[AMR][1000 genomes];0.81[EUR][1000 genomes]
rs7082367	0.89[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs7082480	0.81[AFR][1000 genomes];0.93[AMR][1000 genomes];0.96[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs7083254	0.86[EUR][1000 genomes]
rs7085956	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs7097153	0.87[AMR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs7097299	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs7098574	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs7100856	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs73256680	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs73256682	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs73256699	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs73260601	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs73262610	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs73262631	0.94[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs7476198	0.85[AMR][1000 genomes];0.90[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs7476285	0.87[AMR][1000 genomes];0.96[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs7899665	0.86[EUR][1000 genomes]
rs7911986	0.93[AMR][1000 genomes];0.93[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs7912057	0.86[EUR][1000 genomes]
rs7914365	0.96[AMR][1000 genomes];0.94[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7914372	0.89[AMR][1000 genomes];0.91[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7917276	0.96[AMR][1000 genomes];0.94[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7918447	0.80[AFR][1000 genomes];0.93[AMR][1000 genomes];0.93[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs7920292	0.96[AMR][1000 genomes];0.93[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7920620	0.94[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs7921571	0.93[AMR][1000 genomes];0.93[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs7921658	0.85[AMR][1000 genomes];0.86[EUR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:18 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv817455	chr10:42607635-43151812	Active TSS Weak transcription Strong transcription Genic enhancers ZNF genes & repeats Flanking Bivalent TSS/Enh Flanking Active TSS Bivalent/Poised TSS Enhancers Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	29 gene(s)	inside rSNPs	diseases
2	nsv550670	chr10:42725663-43089965	Strong transcription Bivalent/Poised TSS Active TSS ZNF genes & repeats Weak transcription Enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Genic enhancers Transcr. at gene 5' and 3' Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	15 gene(s)	inside rSNPs	diseases
3	nsv550672	chr10:42753190-43441729	Bivalent Enhancer Genic enhancers Weak transcription Strong transcription Active TSS Enhancers Flanking Active TSS ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	40 gene(s)	inside rSNPs	diseases
4	nsv895054	chr10:42761931-43068841	ZNF genes & repeats Flanking Active TSS Weak transcription Bivalent/Poised TSS Active TSS Enhancers Strong transcription Bivalent Enhancer Genic enhancers Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	10 gene(s)	inside rSNPs	diseases
5	nsv895064	chr10:42783481-43243325	Flanking Active TSS Strong transcription Bivalent/Poised TSS ZNF genes & repeats Weak transcription Active TSS Genic enhancers Enhancers Flanking Bivalent TSS/Enh Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	27 gene(s)	inside rSNPs	diseases
6	nsv466877	chr10:42794125-43066414	Weak transcription ZNF genes & repeats Flanking Active TSS Enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh Active TSS Strong transcription Bivalent/Poised TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	9 gene(s)	inside rSNPs	diseases
7	nsv550683	chr10:42794125-43066414	Weak transcription Flanking Active TSS ZNF genes & repeats Enhancers Active TSS Bivalent/Poised TSS Strong transcription Transcr. at gene 5' and 3' Genic enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	9 gene(s)	inside rSNPs	diseases
8	nsv533331	chr10:42830221-43356410	ZNF genes & repeats Weak transcription Flanking Active TSS Bivalent/Poised TSS Active TSS Genic enhancers Strong transcription Enhancers Flanking Bivalent TSS/Enh Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	35 gene(s)	inside rSNPs	diseases
9	nsv1042764	chr10:42846383-43511712	Flanking Active TSS Strong transcription Bivalent/Poised TSS ZNF genes & repeats Weak transcription Bivalent Enhancer Flanking Bivalent TSS/Enh Enhancers Active TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	50 gene(s)	inside rSNPs	diseases
10	nsv895071	chr10:42864138-43066414	ZNF genes & repeats Strong transcription Enhancers Weak transcription Active TSS Flanking Active TSS Bivalent/Poised TSS Flanking Bivalent TSS/Enh Genic enhancers Transcr. at gene 5' and 3' Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	9 gene(s)	inside rSNPs	diseases
11	nsv895073	chr10:42884169-43066505	Enhancers Active TSS ZNF genes & repeats Flanking Active TSS Genic enhancers Weak transcription Flanking Bivalent TSS/Enh Strong transcription Bivalent/Poised TSS Transcr. at gene 5' and 3' Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	8 gene(s)	inside rSNPs	diseases
12	nsv1050394	chr10:42890663-43604956	Enhancers Weak transcription Active TSS Bivalent Enhancer Strong transcription Flanking Active TSS ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent/Poised TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	53 gene(s)	inside rSNPs	diseases
13	nsv540573	chr10:42890663-43604956	Strong transcription Bivalent Enhancer Weak transcription Flanking Active TSS ZNF genes & repeats Active TSS Enhancers Flanking Bivalent TSS/Enh Bivalent/Poised TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	53 gene(s)	inside rSNPs	diseases
14	nsv534548	chr10:42890664-43729688	Weak transcription Strong transcription Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh Enhancers Flanking Active TSS Active TSS ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	56 gene(s)	inside rSNPs	diseases
15	nsv469725	chr10:42965130-43178323	Active TSS Strong transcription Flanking Active TSS ZNF genes & repeats Enhancers Weak transcription Genic enhancers Flanking Bivalent TSS/Enh Bivalent Enhancer Transcr. at gene 5' and 3' Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	22 gene(s)	inside rSNPs	diseases
16	nsv482513	chr10:42965130-43178323	Weak transcription ZNF genes & repeats Active TSS Strong transcription Enhancers Flanking Active TSS Bivalent/Poised TSS Genic enhancers Bivalent Enhancer Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	22 gene(s)	inside rSNPs	diseases
17	esv2758216	chr10:42965131-43510191	Flanking Active TSS Enhancers Genic enhancers Flanking Bivalent TSS/Enh ZNF genes & repeats Strong transcription Active TSS Bivalent Enhancer Weak transcription Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	49 gene(s)	inside rSNPs	diseases
18	esv2759746	chr10:42965131-43510191	Weak transcription Bivalent Enhancer Bivalent/Poised TSS Strong transcription Active TSS Flanking Active TSS ZNF genes & repeats Enhancers Genic enhancers Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	49 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:75 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:43006600-43021000	ZNF genes & repeats	Adipose Nuclei	Adipose
2	chr10:43009200-43021000	ZNF genes & repeats	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
3	chr10:43009200-43021600	ZNF genes & repeats	Liver	Liver
4	chr10:43009200-43021600	ZNF genes & repeats	Duodenum Smooth Muscle	Duodenum
5	chr10:43009400-43021000	ZNF genes & repeats	Primary T helper cells PMA-I stimulated	--
6	chr10:43009400-43021000	ZNF genes & repeats	Brain Hippocampus Middle	brain
7	chr10:43010600-43020600	ZNF genes & repeats	Monocytes-CD14+_RO01746	blood
8	chr10:43011400-43021000	ZNF genes & repeats	Duodenum Mucosa	Duodenum
9	chr10:43011800-43020800	ZNF genes & repeats	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
10	chr10:43012400-43021600	ZNF genes & repeats	Primary T cells from cord blood	blood
11	chr10:43012400-43021600	ZNF genes & repeats	Colon Smooth Muscle	Colon
12	chr10:43012600-43020800	ZNF genes & repeats	Brain Germinal Matrix	brain
13	chr10:43012800-43019800	ZNF genes & repeats	Primary T helper memory cells from peripheral blood 1	blood
14	chr10:43013200-43015600	Weak transcription	Placenta Amnion	Placenta Amnion
15	chr10:43013200-43021600	ZNF genes & repeats	Primary hematopoietic stem cells G-CSF-mobilized Male	--
16	chr10:43013400-43018200	ZNF genes & repeats	Cortex derived primary cultured neurospheres	brain
17	chr10:43013400-43019800	ZNF genes & repeats	HUES48 Cell Line	embryonic stem cell
18	chr10:43013400-43021200	ZNF genes & repeats	Fetal Brain Female	brain
19	chr10:43013400-43021600	ZNF genes & repeats	Ganglion Eminence derived primary cultured neurospheres	brain
20	chr10:43013600-43020800	ZNF genes & repeats	iPS-20b Cell Line	embryonic stem cell
21	chr10:43013600-43021000	ZNF genes & repeats	Brain Anterior Caudate	brain
22	chr10:43013800-43017400	ZNF genes & repeats	H9 Derived Neuron Cultured Cells	ES cell derived
23	chr10:43013800-43020600	ZNF genes & repeats	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
24	chr10:43013800-43020800	ZNF genes & repeats	Pancreatic Islets	Pancreatic Islet
25	chr10:43014200-43020800	ZNF genes & repeats	HUES64 Cell Line	embryonic stem cell
26	chr10:43014400-43020800	ZNF genes & repeats	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
27	chr10:43014600-43015600	Weak transcription	Fetal Intestine Large	intestine
28	chr10:43014600-43016200	ZNF genes & repeats	Primary T helper naive cells from peripheral blood	blood
29	chr10:43014600-43017400	ZNF genes & repeats	Fetal Kidney	kidney
30	chr10:43014600-43017400	ZNF genes & repeats	Skeletal Muscle Male	skeletal muscle
31	chr10:43014600-43020400	ZNF genes & repeats	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
32	chr10:43014600-43021000	ZNF genes & repeats	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
33	chr10:43014600-43021600	ZNF genes & repeats	Fetal Lung	lung
34	chr10:43014800-43017400	ZNF genes & repeats	ES-I3 Cell Line	embryonic stem cell
35	chr10:43014800-43017600	ZNF genes & repeats	Muscle Satellite Cultured Cells	--
36	chr10:43014800-43017600	ZNF genes & repeats	Brain Inferior Temporal Lobe	brain
37	chr10:43014800-43018000	ZNF genes & repeats	Skeletal Muscle Female	skeletal muscle
38	chr10:43014800-43018200	ZNF genes & repeats	HSMMtube	muscle
39	chr10:43014800-43019200	ZNF genes & repeats	Rectal Mucosa Donor 29	rectum
40	chr10:43014800-43019200	ZNF genes & repeats	Right Ventricle	heart
41	chr10:43014800-43020800	ZNF genes & repeats	Brain Substantia Nigra	brain
42	chr10:43014800-43021000	ZNF genes & repeats	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
43	chr10:43014800-43021600	ZNF genes & repeats	Primary hematopoietic stem cells short term culture	blood
44	chr10:43014800-43021600	ZNF genes & repeats	Psoas Muscle	Psoas
45	chr10:43014800-43021600	ZNF genes & repeats	Dnd41	blood
46	chr10:43015000-43016000	Weak transcription	Placenta	Placenta
47	chr10:43015000-43017400	ZNF genes & repeats	HSMM	muscle
48	chr10:43015000-43017800	ZNF genes & repeats	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
49	chr10:43015000-43019600	ZNF genes & repeats	iPS-18 Cell Line	embryonic stem cell
50	chr10:43015000-43021000	ZNF genes & repeats	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived

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