Variant report

Variant	rs7123627
Chromosome Location	chr11:8674049-8674050
allele	A/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	POLR2A	chr11:8673673-8674118	SK-N-SH	brain:	n/a	n/a
2	CEBPB	chr11:8673620-8674068	IMR90	lung:	n/a	chr11:8673866-8673878
3	NFIC	chr11:8673497-8674249	SK-N-SH	brain:	n/a	n/a
4	FOS	chr11:8673707-8674106	MCF10A-Er-Src	breast:	n/a	n/a
5	FOS	chr11:8673772-8674077	MCF10A-Er-Src	breast:	n/a	n/a
6	NFIC	chr11:8673517-8674147	SK-N-SH	brain:	n/a	n/a
7	STAT3	chr11:8673797-8674052	MCF10A-Er-Src	breast:	n/a	n/a
8	RCOR1	chr11:8673126-8674703	IMR90	lung:	n/a	n/a
9	POLR2A	chr11:8663090-8674809	K562	blood:	n/a	n/a
10	FOSL2	chr11:8673552-8674231	SK-N-SH	brain:	n/a	n/a
11	FOS	chr11:8673759-8674116	MCF10A-Er-Src	breast:	n/a	n/a

No.	Distal block	Cell Line	Cell type
1	chr11:8672333..8674524-chr11:8709540..8711409,2	MCF-7	breast:
2	chr11:8671547..8674880-chr11:8683700..8686434,3	K562	blood:
3	chr11:8673819..8675893-chr11:8677657..8679340,2	MCF-7	breast:
4	chr11:8671628..8674331-chr11:8674914..8677383,3	K562	blood:
5	chr11:8673685..8676178-chr11:8690727..8693204,2	K562	blood:

Variant related genes	Relation type
TRIM66	TF binding region
ENSG00000166441	Chromatin interaction

Extended variants
information (count: 9 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:7)

rs_ID	r²[population]
rs10743085	1.00[YRI][hapmap];0.93[AFR][1000 genomes]
rs10769934	0.93[AFR][1000 genomes]
rs10769937	0.94[AFR][1000 genomes]
rs10840096	0.82[AFR][1000 genomes]
rs7934978	0.94[AFR][1000 genomes]
rs7941744	0.82[AFR][1000 genomes]
rs7950801	0.94[AFR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	esv2751035	chr11:8431654-8685451	Strong transcription Weak transcription Enhancers ZNF genes & repeats Genic enhancers Flanking Active TSS Bivalent/Poised TSS Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	8 gene(s)	inside rSNPs	diseases
2	nsv896983	chr11:8526643-8682465	ZNF genes & repeats Strong transcription Weak transcription Bivalent Enhancer Flanking Active TSS Enhancers Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA	8 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:110 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:8637000-8703200	Weak transcription	Small Intestine	intestine
2	chr11:8650800-8676200	Strong transcription	Monocytes-CD14+_RO01746	blood
3	chr11:8652200-8675000	Strong transcription	Primary monocytes fromperipheralblood	blood
4	chr11:8654200-8675600	Strong transcription	Stomach Smooth Muscle	stomach
5	chr11:8655000-8676400	Strong transcription	Primary T cells from cord blood	blood
6	chr11:8658000-8675200	Strong transcription	Primary Natural Killer cells fromperipheralblood	blood
7	chr11:8658600-8674200	Strong transcription	Primary T cells fromperipheralblood	blood
8	chr11:8658600-8675000	Strong transcription	Liver	Liver
9	chr11:8662600-8680200	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
10	chr11:8662600-8692000	Weak transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
11	chr11:8662800-8675400	Weak transcription	H9 Cell Line	embryonic stem cell
12	chr11:8663000-8680200	Weak transcription	HUES48 Cell Line	embryonic stem cell
13	chr11:8663200-8680000	Weak transcription	iPS-15b Cell Line	embryonic stem cell
14	chr11:8663600-8676800	Weak transcription	iPS-18 Cell Line	embryonic stem cell
15	chr11:8663800-8679800	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
16	chr11:8664200-8692800	Weak transcription	K562	blood
17	chr11:8664200-8700400	Weak transcription	Stomach Mucosa	stomach
18	chr11:8664400-8679600	Weak transcription	Cortex derived primary cultured neurospheres	brain
19	chr11:8664800-8679200	Weak transcription	Fetal Brain Male	brain
20	chr11:8664800-8679800	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
21	chr11:8665800-8692600	Weak transcription	Fetal Kidney	kidney
22	chr11:8666400-8676000	Strong transcription	Breast Myoepithelial Primary Cells	Breast
23	chr11:8667000-8677600	Weak transcription	Primary T killer memory cells from peripheral blood	blood
24	chr11:8667600-8678000	Weak transcription	Placenta Amnion	Placenta Amnion
25	chr11:8668200-8692400	Weak transcription	Primary T helper memory cells from peripheral blood 2	blood
26	chr11:8668400-8692400	Weak transcription	A549	lung
27	chr11:8669200-8683200	Weak transcription	HUES64 Cell Line	embryonic stem cell
28	chr11:8669400-8693000	Weak transcription	Primary hematopoietic stem cells	blood
29	chr11:8669600-8679800	Weak transcription	H9 Derived Neuron Cultured Cells	ES cell derived
30	chr11:8669800-8691800	Weak transcription	Duodenum Mucosa	Duodenum
31	chr11:8670000-8677400	Weak transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
32	chr11:8670000-8693400	Weak transcription	Colonic Mucosa	Colon
33	chr11:8670000-8693600	Weak transcription	Psoas Muscle	Psoas
34	chr11:8670200-8679600	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
35	chr11:8670200-8679800	Weak transcription	Fetal Lung	lung
36	chr11:8670200-8692400	Weak transcription	iPS-20b Cell Line	embryonic stem cell
37	chr11:8670200-8692800	Weak transcription	Left Ventricle	heart
38	chr11:8670200-8692800	Weak transcription	Ovary	ovary
39	chr11:8670200-8693200	Weak transcription	Fetal Muscle Trunk	muscle
40	chr11:8670400-8680000	Weak transcription	Brain Hippocampus Middle	brain
41	chr11:8670400-8690400	Weak transcription	Foreskin Melanocyte Primary Cells skin03	Skin
42	chr11:8670400-8693200	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
43	chr11:8670600-8678200	Weak transcription	Adipose Nuclei	Adipose
44	chr11:8670600-8679400	Weak transcription	Fetal Muscle Leg	muscle
45	chr11:8670600-8686400	Weak transcription	HepG2	liver
46	chr11:8670600-8692800	Weak transcription	Primary B cells from cord blood	blood
47	chr11:8671000-8674600	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
48	chr11:8671000-8674600	Enhancers	NHDF-Ad	bronchial
49	chr11:8671200-8691200	Weak transcription	Primary T helper cells PMA-I stimulated	--
50	chr11:8671200-8693200	Weak transcription	Duodenum Smooth Muscle	Duodenum

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