Variant report

Variant	rs7802537
Chromosome Location	chr7:140356552-140356553
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr7:140352705..140358390-chr7:140370477..140374283,7	MCF-7	breast:
2	chr7:140178651..140180192-chr7:140355165..140357429,2	MCF-7	breast:
3	chr7:140345066..140345636-chr7:140356500..140357064,2	K562	blood:
4	chr7:140356234..140358588-chr7:140371842..140375478,4	MCF-7	breast:

Variant related genes	Relation type
ENSG00000133606	Chromatin interaction
ENSG00000133597	Chromatin interaction
ENSG00000146966	Chromatin interaction

Extended variants
information (count: 21 )
Associated
traits (count: 5 )

rSNPs within LD-proxies of this variant (count:19)

rs_ID	r²[population]
rs1106846	0.83[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs28828674	0.98[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs28896544	1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2908235	0.83[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2930315	0.82[CEU][hapmap]
rs2930320	1.00[CEU][hapmap];1.00[CHD][hapmap];0.84[GIH][hapmap]
rs2930325	0.85[CEU][hapmap];1.00[CHD][hapmap]
rs2930326	0.98[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs2930328	0.94[ASW][hapmap];1.00[CEU][hapmap];1.00[CHD][hapmap];1.00[GIH][hapmap];1.00[MEX][hapmap];1.00[TSI][hapmap];0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2930329	0.94[ASW][hapmap];1.00[CEU][hapmap];1.00[CHD][hapmap];1.00[GIH][hapmap];1.00[MEX][hapmap];1.00[TSI][hapmap];0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2930330	0.87[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs2930332	0.81[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2968546	0.85[CEU][hapmap]
rs2968559	0.83[ASW][hapmap]
rs2968560	0.95[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4727011	0.94[ASW][hapmap]
rs6969644	0.94[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs6977496	0.98[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs7785630	0.82[CEU][hapmap];0.98[EUR][1000 genomes];0.83[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv831157	chr7:140241339-140426876	Weak transcription Enhancers Strong transcription Active TSS Genic enhancers Flanking Active TSS Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent/Poised TSS Transcr. at gene 5' and 3' Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	16 gene(s)	inside rSNPs	diseases
2	esv3371832	chr7:140352483-140356781	Active TSS Flanking Active TSS Weak transcription Enhancers Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent Enhancer Bivalent/Poised TSS	Chromatin interactive region	3 gene(s)	inside rSNPs	diseases

mRNA abundance (count:5)

SNP	Gene	Cis/trans	Tissue	Source
rs7802537	ZYX	cis	cerebellum	SCAN
rs7802537	ADCK2	cis	parietal	SCAN
rs7802537	TRIM24	cis	parietal	SCAN
rs7802537	ADCK2	cis	lymphoblastoid	seeQTL
rs7802537	ADCK2	cis	multi-tissue	Pritchard

Chromatin state (count:93 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr7:140351800-140358000	Weak transcription	Gastric	stomach
2	chr7:140353400-140356600	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
3	chr7:140353400-140356600	Weak transcription	Brain Inferior Temporal Lobe	brain
4	chr7:140353400-140356600	Weak transcription	Lung	lung
5	chr7:140353400-140356600	Weak transcription	Psoas Muscle	Psoas
6	chr7:140353600-140356600	Weak transcription	Brain Cingulate Gyrus	brain
7	chr7:140355400-140357400	Enhancers	Primary Natural Killer cells fromperipheralblood	blood
8	chr7:140355400-140358400	Enhancers	Primary monocytes fromperipheralblood	blood
9	chr7:140355600-140357400	Enhancers	Placenta	Placenta
10	chr7:140355600-140357400	Enhancers	Stomach Mucosa	stomach
11	chr7:140355600-140357600	Enhancers	Fetal Muscle Leg	muscle
12	chr7:140355800-140357000	Enhancers	Spleen	Spleen
13	chr7:140355800-140357000	Flanking Active TSS	Monocytes-CD14+_RO01746	blood
14	chr7:140355800-140357200	Enhancers	Primary hematopoietic stem cells	blood
15	chr7:140355800-140357200	Enhancers	Esophagus	oesophagus
16	chr7:140355800-140357200	Enhancers	Fetal Muscle Trunk	muscle
17	chr7:140355800-140357200	Enhancers	Left Ventricle	heart
18	chr7:140355800-140357400	Enhancers	Placenta Amnion	Placenta Amnion
19	chr7:140356000-140356600	Enhancers	Breast Myoepithelial Primary Cells	Breast
20	chr7:140356000-140356800	Active TSS	Rectal Smooth Muscle	rectum
21	chr7:140356000-140357000	Flanking Active TSS	Foreskin Keratinocyte Primary Cells skin02	Skin
22	chr7:140356000-140357000	Enhancers	Primary mononuclear cells fromperipheralblood	Blood
23	chr7:140356000-140357000	Flanking Active TSS	Colon Smooth Muscle	Colon
24	chr7:140356000-140357200	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
25	chr7:140356000-140357200	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
26	chr7:140356000-140357200	Enhancers	Primary B cells from peripheral blood	blood
27	chr7:140356000-140357200	Enhancers	Primary T killer memory cells from peripheral blood	blood
28	chr7:140356000-140357200	Enhancers	Brain Angular Gyrus	brain
29	chr7:140356000-140357200	Enhancers	Fetal Heart	heart
30	chr7:140356000-140357200	Enhancers	Fetal Intestine Small	intestine
31	chr7:140356000-140357200	Enhancers	Sigmoid Colon	Sigmoid Colon
32	chr7:140356000-140357200	Flanking Active TSS	Stomach Smooth Muscle	stomach
33	chr7:140356000-140357400	Enhancers	Fetal Thymus	thymus
34	chr7:140356000-140357400	Flanking Active TSS	Skeletal Muscle Female	skeletal muscle
35	chr7:140356200-140356600	Active TSS	IMR90 fetal lung fibroblasts Cell Line	lung
36	chr7:140356200-140356600	Active TSS	Primary T helper cells PMA-I stimulated	--
37	chr7:140356200-140356600	Bivalent/Poised TSS	Foreskin Fibroblast Primary Cells skin01	Skin
38	chr7:140356200-140356600	Active TSS	Colonic Mucosa	Colon
39	chr7:140356200-140356600	Active TSS	Duodenum Smooth Muscle	Duodenum
40	chr7:140356200-140356600	Active TSS	Hela-S3	cervix
41	chr7:140356200-140356600	Bivalent/Poised TSS	K562	blood
42	chr7:140356200-140356600	Active TSS	NHLF	lung
43	chr7:140356200-140356800	Flanking Active TSS	Primary hematopoietic stem cells short term culture	blood
44	chr7:140356200-140356800	Enhancers	Primary T helper memory cells from peripheral blood 1	blood
45	chr7:140356200-140356800	Flanking Active TSS	Primary T helper cells fromperipheralblood	blood
46	chr7:140356200-140356800	Flanking Active TSS	Primary T regulatory cells fromperipheralblood	blood
47	chr7:140356200-140356800	Flanking Active TSS	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
48	chr7:140356200-140356800	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Female	--
49	chr7:140356200-140356800	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Male	--
50	chr7:140356200-140356800	Active TSS	Muscle Satellite Cultured Cells	--

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