Variant report

Variant	rs11012737
Chromosome Location	chr10:21849769-21849770
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr10:21812744..21815300-chr10:21848601..21850158,2	K562	blood:
2	chr10:21847924..21850525-chr10:22012351..22015305,2	MCF-7	breast:
3	chr10:21841032..21843534-chr10:21848638..21850144,2	K562	blood:

Variant related genes	Relation type
ENSG00000180592	Chromatin interaction

Extended variants
information (count: 50 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:46)

rs_ID	r²[population]
rs10828247	0.87[MEX][hapmap];0.81[TSI][hapmap]
rs10828248	0.87[MEX][hapmap];0.83[TSI][hapmap];0.82[EUR][1000 genomes]
rs10828249	0.87[MEX][hapmap];0.83[TSI][hapmap];0.81[EUR][1000 genomes]
rs10828250	0.94[AMR][1000 genomes];0.98[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs10828252	1.00[ASW][hapmap];0.95[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];1.00[GIH][hapmap];1.00[LWK][hapmap];0.93[MEX][hapmap];1.00[MKK][hapmap];0.93[TSI][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];0.92[AMR][1000 genomes];0.87[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs10828256	1.00[AFR][1000 genomes];0.89[AMR][1000 genomes];0.88[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs10828258	0.85[AFR][1000 genomes]
rs10828264	1.00[CHB][hapmap];1.00[CHD][hapmap];0.88[GIH][hapmap];0.82[MKK][hapmap]
rs11012726	0.83[ASN][1000 genomes]
rs11012732	0.84[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs11012750	1.00[AFR][1000 genomes];0.86[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs11592565	1.00[AFR][1000 genomes];0.89[AMR][1000 genomes];0.88[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12253527	0.85[EUR][1000 genomes]
rs12356674	1.00[ASW][hapmap];0.95[CEU][hapmap];1.00[GIH][hapmap];1.00[LWK][hapmap];1.00[MKK][hapmap];0.81[TSI][hapmap];1.00[AFR][1000 genomes];0.82[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12357321	0.85[CEU][hapmap];1.00[CHB][hapmap];1.00[ASN][1000 genomes]
rs1243179	1.00[AFR][1000 genomes];0.88[EUR][1000 genomes]
rs1243180	1.00[CEU][hapmap];0.84[EUR][1000 genomes]
rs1243184	0.85[AFR][1000 genomes]
rs1243185	0.92[AFR][1000 genomes];0.87[EUR][1000 genomes]
rs1243187	0.92[AFR][1000 genomes];0.89[EUR][1000 genomes]
rs1243188	0.82[EUR][1000 genomes]
rs1243189	0.96[AFR][1000 genomes]
rs1243194	0.95[CEU][hapmap];1.00[CHB][hapmap];0.94[GIH][hapmap]
rs1243195	1.00[CHB][hapmap]
rs1269454	0.90[CEU][hapmap];1.00[CHB][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes]
rs1270799	0.82[EUR][1000 genomes]
rs12769128	1.00[AFR][1000 genomes];0.89[AMR][1000 genomes];0.88[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12770228	1.00[ASW][hapmap];1.00[CHB][hapmap];1.00[MKK][hapmap];0.86[TSI][hapmap];0.81[AMR][1000 genomes]
rs12779865	0.92[AFR][1000 genomes];0.82[AMR][1000 genomes];0.87[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12783517	1.00[AFR][1000 genomes];0.86[AMR][1000 genomes];0.94[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12784277	0.92[AMR][1000 genomes];0.87[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs16921773	1.00[CHB][hapmap]
rs16921779	1.00[CHB][hapmap]
rs1802669	0.82[EUR][1000 genomes]
rs2026092	0.95[CEU][hapmap];1.00[CHB][hapmap];0.97[GIH][hapmap];0.91[TSI][hapmap];0.84[EUR][1000 genomes]
rs2050905	0.85[MKK][hapmap]
rs34719019	0.92[AFR][1000 genomes]
rs35587371	0.86[AMR][1000 genomes];0.93[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs61850044	0.92[AMR][1000 genomes];0.91[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs6482188	0.89[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs6482189	0.80[GIH][hapmap]
rs7084454	0.85[CEU][hapmap];1.00[CHB][hapmap];0.85[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7098100	0.80[GIH][hapmap];0.87[MEX][hapmap];0.83[TSI][hapmap];0.83[EUR][1000 genomes]
rs7894565	0.88[EUR][1000 genomes]
rs7905967	0.91[EUR][1000 genomes]
rs946711	1.00[CHB][hapmap];0.86[TSI][hapmap]

Variant overlapped rSNPs/rCNVs (count:4 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv825285	chr10:21742026-21874334	Strong transcription Weak transcription Active TSS Flanking Bivalent TSS/Enh Flanking Active TSS Bivalent/Poised TSS Enhancers Bivalent Enhancer Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
2	nsv1052477	chr10:21810270-21889726	Active TSS Genic enhancers Enhancers Weak transcription Strong transcription Flanking Bivalent TSS/Enh Bivalent/Poised TSS Flanking Active TSS ZNF genes & repeats Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	26 gene(s)	inside rSNPs	diseases
3	nsv1036585	chr10:21833717-21998042	Weak transcription Strong transcription Enhancers ZNF genes & repeats Genic enhancers Active TSS Flanking Active TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	8 gene(s)	inside rSNPs	diseases
4	nsv947765	chr10:21845377-21874408	Genic enhancers Strong transcription Weak transcription Enhancers ZNF genes & repeats Flanking Active TSS Active TSS	TF binding region Chromatin interactive region	3 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs11012737	MLLT10	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:125 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:21824600-21864600	Weak transcription	ES-WA7 Cell Line	embryonic stem cell
2	chr10:21824600-21930400	Weak transcription	Gastric	stomach
3	chr10:21824800-21852200	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
4	chr10:21824800-21852200	Strong transcription	Fetal Intestine Small	intestine
5	chr10:21824800-21860200	Weak transcription	Psoas Muscle	Psoas
6	chr10:21825000-21850000	Strong transcription	HUES64 Cell Line	embryonic stem cell
7	chr10:21825200-21850600	Strong transcription	Fetal Stomach	stomach
8	chr10:21825200-21854800	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
9	chr10:21825600-21849800	Strong transcription	Primary monocytes fromperipheralblood	blood
10	chr10:21825600-21850000	Strong transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
11	chr10:21825600-21857800	Strong transcription	Primary mononuclear cells fromperipheralblood	Blood
12	chr10:21825800-21856200	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
13	chr10:21826200-21850600	Strong transcription	Foreskin Melanocyte Primary Cells skin03	Skin
14	chr10:21827800-21850800	Strong transcription	Breast Myoepithelial Primary Cells	Breast
15	chr10:21828000-21851200	Strong transcription	Primary hematopoietic stem cells short term culture	blood
16	chr10:21828000-21856600	Strong transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
17	chr10:21832000-21856400	Weak transcription	Colonic Mucosa	Colon
18	chr10:21832000-21876400	Weak transcription	Aorta	Aorta
19	chr10:21832800-21856200	Weak transcription	Pancreas	Pancrea
20	chr10:21833400-21851200	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
21	chr10:21833400-21856200	Weak transcription	Small Intestine	intestine
22	chr10:21833400-21856400	Weak transcription	Colon Smooth Muscle	Colon
23	chr10:21835600-21850000	Strong transcription	Dnd41	blood
24	chr10:21835800-21850000	Strong transcription	Monocytes-CD14+_RO01746	blood
25	chr10:21836600-21850000	Strong transcription	Primary T helper cells fromperipheralblood	blood
26	chr10:21837600-21849800	Strong transcription	HUES48 Cell Line	embryonic stem cell
27	chr10:21837600-21850000	Strong transcription	iPS-18 Cell Line	embryonic stem cell
28	chr10:21837600-21850400	Strong transcription	Fetal Muscle Leg	muscle
29	chr10:21837800-21849800	Strong transcription	iPS-20b Cell Line	embryonic stem cell
30	chr10:21837800-21849800	Strong transcription	Fetal Thymus	thymus
31	chr10:21838000-21849800	Strong transcription	H1 Cell Line	embryonic stem cell
32	chr10:21838000-21850000	Strong transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
33	chr10:21838200-21851400	Strong transcription	Placenta	Placenta
34	chr10:21839000-21864200	Weak transcription	Fetal Heart	heart
35	chr10:21839200-21859000	Weak transcription	Right Atrium	heart
36	chr10:21839400-21850000	Strong transcription	HUES6 Cell Line	embryonic stem cell
37	chr10:21839400-21851200	Strong transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
38	chr10:21839400-21856200	Weak transcription	Primary T killer naive cells fromperipheralblood	blood
39	chr10:21839400-21878200	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
40	chr10:21839600-21851000	Strong transcription	IMR90 fetal lung fibroblasts Cell Line	lung
41	chr10:21839600-21855000	Strong transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
42	chr10:21839600-21860600	Weak transcription	Brain Substantia Nigra	brain
43	chr10:21839800-21880200	Weak transcription	Primary T helper naive cells from peripheral blood	blood
44	chr10:21840000-21877200	Weak transcription	ES-I3 Cell Line	embryonic stem cell
45	chr10:21840800-21850000	Strong transcription	Fetal Lung	lung
46	chr10:21841200-21850000	Weak transcription	H9 Cell Line	embryonic stem cell
47	chr10:21841200-21861600	Weak transcription	Skeletal Muscle Male	skeletal muscle
48	chr10:21841200-21897200	Weak transcription	Fetal Kidney	kidney
49	chr10:21841400-21859800	Weak transcription	iPS-15b Cell Line	embryonic stem cell
50	chr10:21841600-21870000	Weak transcription	Right Ventricle	heart

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