Variant report

Variant	rs647972
Chromosome Location	chr3:138459069-138459070
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr3:138457643..138459250-chr3:138465612..138468062,2	K562	blood:

Extended variants
information (count: 151 )
Associated
traits (count: 3 )

rSNPs within LD-proxies of this variant (count:140)

rs_ID	r²[population]
rs1066197	0.85[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs1068104	0.91[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs1068685	0.93[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs11705762	0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs11709768	0.98[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs11713049	0.91[AMR][1000 genomes];0.98[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs11717457	0.89[EUR][1000 genomes]
rs11720178	0.91[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs11924814	0.88[AMR][1000 genomes];0.98[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs13069296	0.86[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs13082808	0.88[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs13433948	0.90[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs1400266	0.98[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs1663554	0.81[ASN][1000 genomes]
rs1663556	0.90[AMR][1000 genomes];0.92[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs1673597	0.93[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs168633	0.92[AMR][1000 genomes];0.96[EUR][1000 genomes]
rs181729	0.92[EUR][1000 genomes]
rs187245	0.84[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs191713	0.86[AFR][1000 genomes];0.98[AMR][1000 genomes];0.96[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs191714	0.94[AMR][1000 genomes];0.96[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs191775	0.85[AFR][1000 genomes];0.98[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs2197387	0.82[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs2348147	0.93[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs244380	0.81[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs244381	0.88[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs2595928	0.91[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs2595930	0.86[AFR][1000 genomes];0.95[AMR][1000 genomes];0.93[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs2595932	0.90[ASN][1000 genomes]
rs2607796	0.93[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs28376988	0.83[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs28408150	0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs2881900	0.81[EUR][1000 genomes]
rs34900559	0.83[EUR][1000 genomes]
rs35214574	0.94[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs35926694	0.81[AMR][1000 genomes]
rs361054	0.83[AMR][1000 genomes];0.98[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361055	0.90[ASN][1000 genomes]
rs361056	0.88[AFR][1000 genomes];0.86[AMR][1000 genomes];0.80[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361057	0.91[EUR][1000 genomes]
rs361059	0.84[AFR][1000 genomes];0.96[AMR][1000 genomes];0.98[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361060	0.94[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361061	0.81[AMR][1000 genomes];0.97[EUR][1000 genomes]
rs361062	0.81[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361063	0.85[AMR][1000 genomes];0.93[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361064	0.88[AFR][1000 genomes];0.86[AMR][1000 genomes];0.80[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361065	0.90[ASN][1000 genomes]
rs361066	0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361067	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361068	0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361069	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs361071	0.82[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361072	0.87[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361079	0.89[AFR][1000 genomes];0.88[AMR][1000 genomes];0.82[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361080	0.85[AFR][1000 genomes];0.98[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361081	0.87[AFR][1000 genomes];0.98[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361082	0.85[AFR][1000 genomes];0.98[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361083	0.82[AFR][1000 genomes];0.94[AMR][1000 genomes];0.96[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361084	0.94[AMR][1000 genomes];0.96[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361088	0.89[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs361089	0.83[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs361092	0.90[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs361094	0.93[AMR][1000 genomes];0.93[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs361096	0.90[ASN][1000 genomes]
rs361097	0.81[AMR][1000 genomes];0.92[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs371762	0.80[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs385254	0.85[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs398065	0.96[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs404110	0.95[AMR][1000 genomes];1.00[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs409507	0.92[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs413147	0.82[AMR][1000 genomes];0.98[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs425901	0.87[AMR][1000 genomes];0.95[EUR][1000 genomes]
rs4305444	0.84[AFR][1000 genomes];0.98[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs439720	0.85[AMR][1000 genomes];0.96[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs4405948	0.80[EUR][1000 genomes]
rs448808	0.83[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs470359	0.90[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs473388	0.93[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs475254	0.92[EUR][1000 genomes]
rs476800	0.87[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs482334	0.96[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs4894350	0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs4894351	0.95[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs4894352	0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs4894353	0.91[AMR][1000 genomes];0.96[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs4894354	0.86[AMR][1000 genomes];0.94[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs491371	0.86[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs493152	0.83[AMR][1000 genomes];0.90[ASN][1000 genomes]
rs497900	0.84[AFR][1000 genomes];0.98[AMR][1000 genomes];0.98[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs500687	0.96[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs511207	0.80[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs524164	0.87[AMR][1000 genomes];0.92[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs531577	0.90[ASN][1000 genomes]
rs539156	0.88[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs539619	0.83[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs540198	0.95[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs540907	0.86[AFR][1000 genomes];0.83[AMR][1000 genomes];0.96[EUR][1000 genomes]
rs550768	0.83[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs558905	0.87[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs559160	0.92[EUR][1000 genomes]
rs559451	0.96[AMR][1000 genomes];0.96[EUR][1000 genomes]
rs564455	0.87[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs574942	0.80[AMR][1000 genomes];0.90[ASN][1000 genomes]
rs589986	0.91[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs600590	0.83[AMR][1000 genomes]
rs603723	0.82[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs607044	0.90[AMR][1000 genomes];1.00[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs618457	0.87[AMR][1000 genomes];0.89[EUR][1000 genomes]
rs621204	0.91[EUR][1000 genomes]
rs62282169	0.91[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs624099	0.92[EUR][1000 genomes]
rs625468	0.92[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs635592	0.93[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs6439817	0.81[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs6439819	0.95[EUR][1000 genomes]
rs654459	0.84[EUR][1000 genomes]
rs6776585	0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs6781914	0.89[EUR][1000 genomes]
rs6784610	0.84[EUR][1000 genomes]
rs6794270	0.85[EUR][1000 genomes]
rs6795203	0.84[AFR][1000 genomes];0.95[AMR][1000 genomes];0.97[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs6801207	0.91[AMR][1000 genomes];0.98[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs6810351	0.97[EUR][1000 genomes]
rs7612106	0.87[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs7643722	0.81[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs772612	0.86[AFR][1000 genomes];0.90[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs773045	0.92[EUR][1000 genomes]
rs773184	0.82[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs9818354	0.82[EUR][1000 genomes]
rs9821694	0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs9822714	0.80[AMR][1000 genomes];0.99[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs9823213	0.85[AMR][1000 genomes];0.96[EUR][1000 genomes]
rs9832012	0.81[AMR][1000 genomes];0.98[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs9834963	0.91[AMR][1000 genomes];0.98[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs9853819	0.95[EUR][1000 genomes]
rs9863481	0.88[AMR][1000 genomes];0.84[EUR][1000 genomes]
rs9864176	0.92[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs9874723	0.85[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs9877108	0.84[EUR][1000 genomes]
rs9879784	0.92[EUR][1000 genomes];0.90[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:11 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv530057	chr3:138014877-138734390	Weak transcription Strong transcription Enhancers Active TSS ZNF genes & repeats Flanking Active TSS Genic enhancers Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	38 gene(s)	inside rSNPs	diseases
2	nsv1013074	chr3:138213166-138737688	Strong transcription Enhancers Weak transcription ZNF genes & repeats Bivalent/Poised TSS Flanking Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Active TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	32 gene(s)	inside rSNPs	diseases
3	nsv1002612	chr3:138213274-138831792	Weak transcription Strong transcription Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats Flanking Active TSS Enhancers Genic enhancers Active TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	38 gene(s)	inside rSNPs	diseases
4	nsv536726	chr3:138213274-138831792	Enhancers Flanking Active TSS Strong transcription Weak transcription ZNF genes & repeats Bivalent Enhancer Bivalent/Poised TSS Active TSS Flanking Bivalent TSS/Enh Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	38 gene(s)	inside rSNPs	diseases
5	nsv1009726	chr3:138219923-138737688	Weak transcription Enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Active TSS Strong transcription ZNF genes & repeats Bivalent Enhancer Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	32 gene(s)	inside rSNPs	diseases
6	nsv869205	chr3:138248190-138775288	Enhancers Weak transcription Flanking Bivalent TSS/Enh Active TSS Bivalent/Poised TSS Flanking Active TSS Bivalent Enhancer Strong transcription ZNF genes & repeats Transcr. at gene 5' and 3' Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	33 gene(s)	inside rSNPs	diseases
7	nsv868955	chr3:138248190-138848947	Bivalent Enhancer Bivalent/Poised TSS Strong transcription Flanking Active TSS Enhancers Weak transcription ZNF genes & repeats Flanking Bivalent TSS/Enh Active TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	37 gene(s)	inside rSNPs	diseases
8	nsv591854	chr3:138348081-138764229	Weak transcription Flanking Active TSS Bivalent Enhancer Transcr. at gene 5' and 3' Enhancers ZNF genes & repeats Strong transcription Active TSS Flanking Bivalent TSS/Enh Genic enhancers Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	25 gene(s)	inside rSNPs	diseases
9	nsv1010514	chr3:138365640-138737688	Flanking Bivalent TSS/Enh Strong transcription Enhancers Weak transcription Active TSS Genic enhancers Bivalent Enhancer ZNF genes & repeats Flanking Active TSS Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	23 gene(s)	inside rSNPs	diseases
10	nsv1000927	chr3:138423543-138632596	Genic enhancers Weak transcription Enhancers Strong transcription Active TSS Flanking Active TSS ZNF genes & repeats Transcr. at gene 5' and 3' Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	16 gene(s)	inside rSNPs	diseases
11	nsv917964	chr3:138440701-138699084	Enhancers Bivalent Enhancer Active TSS ZNF genes & repeats Bivalent/Poised TSS Weak transcription Flanking Bivalent TSS/Enh Strong transcription Flanking Active TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	18 gene(s)	inside rSNPs	diseases

mRNA abundance (count:3)

SNP	Gene	Cis/trans	Tissue	Source
rs647972	FAIM	cis	Muscle Skeletal	GTEx
rs647972	CEP70	Cis_1M	lymphoblastoid	RTeQTL
rs647972	PIK3CB	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:111 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr3:138364400-138459200	Weak transcription	Psoas Muscle	Psoas
2	chr3:138369000-138493000	Weak transcription	Fetal Lung	lung
3	chr3:138390800-138459600	Weak transcription	Right Ventricle	heart
4	chr3:138393800-138515000	Weak transcription	Aorta	Aorta
5	chr3:138395800-138459800	Weak transcription	Primary T helper memory cells from peripheral blood 1	blood
6	chr3:138395800-138480200	Weak transcription	Primary T killer naive cells fromperipheralblood	blood
7	chr3:138396000-138469200	Weak transcription	ES-I3 Cell Line	embryonic stem cell
8	chr3:138396200-138469200	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
9	chr3:138396200-138486400	Weak transcription	Rectal Smooth Muscle	rectum
10	chr3:138396200-138487000	Weak transcription	Primary T killer memory cells from peripheral blood	blood
11	chr3:138408000-138479800	Weak transcription	Primary T helper memory cells from peripheral blood 2	blood
12	chr3:138408400-138499200	Weak transcription	Primary T helper naive cells from peripheral blood	blood
13	chr3:138413800-138487600	Weak transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
14	chr3:138416200-138469400	Weak transcription	Muscle Satellite Cultured Cells	--
15	chr3:138416600-138459400	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
16	chr3:138416800-138486600	Weak transcription	Fetal Muscle Trunk	muscle
17	chr3:138417800-138486600	Weak transcription	Hela-S3	cervix
18	chr3:138418400-138459200	Weak transcription	IMR90 fetal lung fibroblasts Cell Line	lung
19	chr3:138419000-138487000	Weak transcription	Skeletal Muscle Male	skeletal muscle
20	chr3:138419200-138486200	Weak transcription	Fetal Muscle Leg	muscle
21	chr3:138421800-138479800	Weak transcription	Small Intestine	intestine
22	chr3:138423400-138469400	Weak transcription	A549	lung
23	chr3:138423400-138487000	Weak transcription	Colonic Mucosa	Colon
24	chr3:138429200-138460800	Weak transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
25	chr3:138432400-138469200	Weak transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
26	chr3:138432600-138459600	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
27	chr3:138432800-138459400	Weak transcription	Primary T helper 17 cells PMA-I stimulated	--
28	chr3:138438600-138486400	Weak transcription	Esophagus	oesophagus
29	chr3:138440600-138470800	Weak transcription	Colon Smooth Muscle	Colon
30	chr3:138442600-138459600	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
31	chr3:138443000-138459200	Weak transcription	H1 Cell Line	embryonic stem cell
32	chr3:138443000-138459400	Weak transcription	Primary B cells from cord blood	blood
33	chr3:138443000-138483200	Weak transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
34	chr3:138443400-138459400	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
35	chr3:138443600-138467200	Weak transcription	Brain Cingulate Gyrus	brain
36	chr3:138443800-138459200	Weak transcription	Brain Inferior Temporal Lobe	brain
37	chr3:138443800-138459600	Weak transcription	iPS-18 Cell Line	embryonic stem cell
38	chr3:138443800-138469200	Weak transcription	iPS-20b Cell Line	embryonic stem cell
39	chr3:138443800-138474400	Weak transcription	Brain Angular Gyrus	brain
40	chr3:138444600-138468600	Strong transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
41	chr3:138445000-138464600	Weak transcription	Brain Germinal Matrix	brain
42	chr3:138445000-138478000	Weak transcription	Brain Dorsolateral Prefrontal Cortex	brain
43	chr3:138445800-138469400	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
44	chr3:138446000-138461600	Strong transcription	Primary monocytes fromperipheralblood	blood
45	chr3:138446000-138486200	Weak transcription	GM12878-XiMat	blood
46	chr3:138446200-138462600	Strong transcription	Monocytes-CD14+_RO01746	blood
47	chr3:138446200-138483600	Weak transcription	NH-A	brain
48	chr3:138446400-138459600	Weak transcription	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
49	chr3:138446400-138471800	Weak transcription	NHEK	skin
50	chr3:138446600-138462600	Weak transcription	Osteobl	bone

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