Variant report

Variant	rs12577885
Chromosome Location	chr11:76082277-76082278
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	FOXA2	chr11:76082196-76082591	HepG2	liver:	n/a	n/a
2	TCF7L2	chr11:76082134-76082713	MCF-7	breast:	n/a	n/a
3	IRF1	chr11:76082219-76082543	K562	blood:	n/a	n/a
4	RUNX3	chr11:76082175-76082650	GM12878	blood:	n/a	n/a
5	FOS	chr11:76082218-76082647	MCF10A-Er-Src	breast:	n/a	chr11:76082405-76082416
6	FOSL2	chr11:76082226-76082709	MCF-7	breast:	n/a	n/a
7	FOXA2	chr11:76082154-76082853	A549	lung:	n/a	n/a
8	FOS	chr11:76082192-76082657	MCF10A-Er-Src	breast:	n/a	chr11:76082405-76082416
9	ATF1	chr11:76082276-76082583	K562	blood:	n/a	n/a
10	FOSL1	chr11:76082156-76082655	HCT-116	colon:	n/a	n/a
11	HDAC2	chr11:76082186-76082483	MCF-7	breast:	n/a	n/a
12	FOS	chr11:76082214-76082682	HUVEC	blood vessel:	n/a	chr11:76082405-76082416
13	FOXA1	chr11:76082215-76082524	T-47D	breast:	n/a	chr11:76082339-76082354
14	EGR1	chr11:76082123-76082784	HCT-116	colon:	n/a	n/a
15	JUND	chr11:76082222-76082609	K562	blood:	n/a	chr11:76082459-76082470 chr11:76082405-76082416
16	FOSL2	chr11:76082126-76082717	SK-N-SH	brain:	n/a	n/a
17	STAT3	chr11:76082245-76082535	MCF10A-Er-Src	breast:	n/a	n/a
18	POU2F2	chr11:76082268-76082561	GM12891	blood:	n/a	chr11:76082490-76082512 chr11:76082497-76082510 chr11:76082497-76082510 chr11:76082497-76082510
19	MAFK	chr11:76082266-76082575	K562	blood:	n/a	n/a
20	POLR2A	chr11:76082231-76082466	MCF10A-Er-Src	breast:	n/a	n/a
21	ATF2	chr11:76082183-76082653	GM12878	blood:	n/a	n/a
22	BATF	chr11:76082219-76082568	GM12878	blood:	n/a	chr11:76082403-76082414
23	KAP1	chr11:76082117-76082692	U2OS	brain:	n/a	n/a
24	FOXA1	chr11:76082041-76082619	HepG2	liver:	n/a	chr11:76082339-76082354
25	ZNF217	chr11:76082202-76082542	MCF-7	breast:	n/a	n/a
26	JUND	chr11:76082132-76082520	SK-N-SH	brain:	n/a	chr11:76082459-76082470 chr11:76082405-76082416
27	FOXA2	chr11:76082131-76082659	A549	lung:	n/a	n/a
28	SP1	chr11:76082167-76082607	A549	lung:	n/a	n/a
29	FOS	chr11:76082180-76082639	MCF10A-Er-Src	breast:	n/a	chr11:76082405-76082416
30	POLR2A	chr11:76082190-76082469	MCF10A-Er-Src	breast:	n/a	n/a
31	BCL3	chr11:76082183-76082622	GM12878	blood:	n/a	n/a
32	POU2F2	chr11:76082273-76082570	GM12878	blood:	n/a	chr11:76082490-76082512 chr11:76082497-76082510 chr11:76082497-76082510 chr11:76082497-76082510
33	FOSL2	chr11:76082148-76082649	MCF-7	breast:	n/a	n/a
34	STAT3	chr11:76082216-76082684	GM12878	blood:	n/a	n/a
35	JUN	chr11:76082247-76082557	K562	blood:	n/a	n/a
36	FOS	chr11:76082177-76082675	MCF10A-Er-Src	breast:	n/a	chr11:76082405-76082416
37	ATF2	chr11:76082106-76082638	GM12878	blood:	n/a	n/a
38	FOXA1	chr11:76082142-76082727	T-47D	breast:	n/a	chr11:76082339-76082354
39	FOSL2	chr11:76082242-76082594	A549	lung:	n/a	n/a
40	JUND	chr11:76082083-76082631	HCT-116	colon:	n/a	chr11:76082459-76082470 chr11:76082405-76082416
41	FOXA1	chr11:76082066-76082723	HepG2	liver:	n/a	chr11:76082339-76082354
42	NFIC	chr11:76082108-76082693	GM12878	blood:	n/a	n/a
43	NFIC	chr11:76082064-76082523	GM12878	blood:	n/a	n/a
44	STAT3	chr11:76082268-76082582	MCF10A-Er-Src	breast:	n/a	n/a
45	POU2F2	chr11:76082189-76082704	GM12891	blood:	n/a	chr11:76082490-76082512 chr11:76082497-76082510 chr11:76082497-76082510 chr11:76082497-76082510
46	BATF	chr11:76082227-76082561	GM12878	blood:	n/a	chr11:76082403-76082414
47	EGR1	chr11:76082240-76082660	HCT-116	colon:	n/a	n/a
48	MYC	chr11:76082275-76082570	MCF10A-Er-Src	breast:	n/a	n/a
49	FOSL2	chr11:76082069-76082764	A549	lung:	n/a	n/a
50	FOXA1	chr11:76082100-76082602	HepG2	liver:	n/a	chr11:76082339-76082354

No.	Distal block	Cell Line	Cell type
1	chr11:76081076..76084141-chr11:76087124..76089011,3	K562	blood:
2	chr11:76069995..76071951-chr11:76081817..76083551,2	K562	blood:
3	chr11:76077209..76079970-chr11:76081805..76083752,2	MCF-7	breast:
4	chr11:76073015..76075782-chr11:76080642..76082701,2	MCF-7	breast:
5	chr11:76079303..76082514-chr11:76090617..76092781,5	K562	blood:
6	chr11:76080958..76083908-chr11:76090335..76092803,5	MCF-7	breast:

Variant related genes	Relation type
PRKRIR	TF binding region
ENSG00000137492	Chromatin interaction
ENSG00000179240	Chromatin interaction

Extended variants
information (count: 20 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:19)

rs_ID	r²[population]
rs11236724	1.00[AMR][1000 genomes];0.92[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12270671	0.94[AMR][1000 genomes];0.84[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12271264	0.94[AMR][1000 genomes];0.84[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12272118	0.88[EUR][1000 genomes]
rs12291710	0.94[AMR][1000 genomes];0.84[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12573970	0.89[AFR][1000 genomes];1.00[AMR][1000 genomes];0.92[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12575838	0.89[AFR][1000 genomes];1.00[AMR][1000 genomes];0.92[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12576140	0.80[AMR][1000 genomes]
rs12576436	0.89[AFR][1000 genomes];1.00[AMR][1000 genomes];0.92[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12577750	1.00[AMR][1000 genomes];0.92[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2156714	0.80[AMR][1000 genomes]
rs3814712	1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs59406877	0.88[EUR][1000 genomes]
rs59877552	0.88[EUR][1000 genomes]
rs61685496	0.94[AMR][1000 genomes];0.84[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7102664	0.95[AMR][1000 genomes];0.88[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7112778	0.80[AMR][1000 genomes]
rs7112895	0.80[AMR][1000 genomes]
rs7127263	0.80[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:1 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv521451	chr11:76053527-76087844	Strong transcription Weak transcription Enhancers Flanking Active TSS ZNF genes & repeats Genic enhancers	TF binding region CpG island Chromatin interactive region miRNA target site	4 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:104 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:76066200-76085800	Weak transcription	Esophagus	oesophagus
2	chr11:76066400-76089200	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
3	chr11:76066400-76090000	Weak transcription	Ganglion Eminence derived primary cultured neurospheres	brain
4	chr11:76066600-76090000	Weak transcription	Fetal Brain Female	brain
5	chr11:76067600-76082400	Weak transcription	Cortex derived primary cultured neurospheres	brain
6	chr11:76067600-76085800	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
7	chr11:76067600-76090400	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
8	chr11:76067600-76091000	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
9	chr11:76067800-76087400	Weak transcription	Colonic Mucosa	Colon
10	chr11:76067800-76090000	Weak transcription	Lung	lung
11	chr11:76071800-76082400	Weak transcription	Primary T cells from cord blood	blood
12	chr11:76072200-76090400	Weak transcription	HUES64 Cell Line	embryonic stem cell
13	chr11:76073600-76090000	Weak transcription	Primary B cells from cord blood	blood
14	chr11:76076000-76087400	Weak transcription	Dnd41	blood
15	chr11:76076400-76089800	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
16	chr11:76076800-76086200	Weak transcription	Primary neutrophils fromperipheralblood	blood
17	chr11:76076800-76089600	Weak transcription	Fetal Thymus	thymus
18	chr11:76076800-76089800	Weak transcription	Fetal Muscle Trunk	muscle
19	chr11:76077000-76090400	Weak transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
20	chr11:76077000-76090400	Weak transcription	Fetal Muscle Leg	muscle
21	chr11:76077400-76082400	Weak transcription	Primary T regulatory cells fromperipheralblood	blood
22	chr11:76077600-76085800	Weak transcription	Gastric	stomach
23	chr11:76077600-76090000	Weak transcription	Placenta	Placenta
24	chr11:76078000-76087800	Weak transcription	Primary B cells from peripheral blood	blood
25	chr11:76078600-76083000	Enhancers	Fetal Adrenal Gland	Adrenal Gland
26	chr11:76079400-76082800	Enhancers	Pancreatic Islets	Pancreatic Islet
27	chr11:76079800-76088000	Weak transcription	Fetal Lung	lung
28	chr11:76080000-76082400	Weak transcription	Fetal Heart	heart
29	chr11:76080000-76082800	Enhancers	Rectal Mucosa Donor 29	rectum
30	chr11:76080200-76083600	Enhancers	Primary T helper 17 cells PMA-I stimulated	--
31	chr11:76080400-76082800	Enhancers	Primary T helper memory cells from peripheral blood 1	blood
32	chr11:76080800-76082600	Enhancers	Sigmoid Colon	Sigmoid Colon
33	chr11:76081000-76085800	Weak transcription	Left Ventricle	heart
34	chr11:76081000-76086200	Weak transcription	ES-I3 Cell Line	embryonic stem cell
35	chr11:76081000-76087600	Weak transcription	Fetal Intestine Large	intestine
36	chr11:76081000-76090400	Weak transcription	Brain Cingulate Gyrus	brain
37	chr11:76081200-76083000	Weak transcription	Right Atrium	heart
38	chr11:76081200-76085800	Weak transcription	Ovary	ovary
39	chr11:76081200-76087400	Weak transcription	Primary T killer memory cells from peripheral blood	blood
40	chr11:76081200-76090400	Weak transcription	Liver	Liver
41	chr11:76081200-76090400	Weak transcription	Brain Dorsolateral Prefrontal Cortex	brain
42	chr11:76081200-76090400	Weak transcription	Spleen	Spleen
43	chr11:76081600-76084000	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Female	--
44	chr11:76081800-76082600	Enhancers	Psoas Muscle	Psoas
45	chr11:76081800-76083000	Enhancers	Primary T helper naive cells fromperipheralblood	blood
46	chr11:76081800-76083400	Enhancers	Rectal Mucosa Donor 31	rectum
47	chr11:76081800-76083400	Enhancers	Skeletal Muscle Male	skeletal muscle
48	chr11:76082000-76082400	Flanking Active TSS	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
49	chr11:76082000-76082400	Flanking Active TSS	Foreskin Fibroblast Primary Cells skin01	Skin
50	chr11:76082000-76082400	Enhancers	Aorta	Aorta

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links