Variant report

Variant	rs12277932
Chromosome Location	chr11:8631669-8631670
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr11:8630210..8632971-chr11:8639993..8641815,2	K562	blood:
2	chr11:8630374..8632927-chr11:8712700..8714781,2	K562	blood:

Variant related genes	Relation type
ENSG00000166436	Chromatin interaction

Extended variants
information (count: 56 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:54)

rs_ID	r²[population]
rs10160430	0.95[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs10160805	0.95[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs10743081	0.91[AMR][1000 genomes];0.81[EUR][1000 genomes]
rs10769915	0.95[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs10769916	0.95[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs10769918	0.86[AMR][1000 genomes];0.80[EUR][1000 genomes]
rs10769921	0.94[AMR][1000 genomes];0.84[EUR][1000 genomes]
rs10769922	0.92[AMR][1000 genomes];0.84[EUR][1000 genomes]
rs10769924	0.96[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs10769925	0.94[AMR][1000 genomes];0.84[EUR][1000 genomes]
rs10769926	0.94[AMR][1000 genomes];0.84[EUR][1000 genomes]
rs10769927	0.88[AMR][1000 genomes]
rs10840072	0.81[AMR][1000 genomes]
rs10840077	0.95[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs10840080	0.93[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs10840083	0.90[AMR][1000 genomes];0.80[EUR][1000 genomes]
rs10840084	0.96[AMR][1000 genomes];0.83[EUR][1000 genomes]
rs10840085	0.90[AMR][1000 genomes];0.80[EUR][1000 genomes]
rs10840087	0.96[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs10840091	0.91[AMR][1000 genomes];0.83[EUR][1000 genomes]
rs11041962	0.85[AMR][1000 genomes]
rs11041974	0.88[AMR][1000 genomes];0.81[EUR][1000 genomes]
rs11041983	0.91[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs11041985	0.92[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs11041990	0.87[AMR][1000 genomes]
rs11041993	0.85[AMR][1000 genomes]
rs11041994	0.87[AMR][1000 genomes]
rs11041995	0.89[AMR][1000 genomes]
rs11041997	0.89[AMR][1000 genomes]
rs11041999	0.94[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs11042002	0.96[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs1446462	0.87[AMR][1000 genomes];0.80[EUR][1000 genomes]
rs1446463	0.87[AMR][1000 genomes];0.80[EUR][1000 genomes]
rs2015629	0.80[AMR][1000 genomes]
rs4244804	0.90[AMR][1000 genomes];0.83[EUR][1000 genomes]
rs4418812	0.96[AMR][1000 genomes];0.84[EUR][1000 genomes]
rs4475924	0.94[AMR][1000 genomes];0.83[EUR][1000 genomes]
rs4612809	0.94[AMR][1000 genomes];0.83[EUR][1000 genomes]
rs4620720	0.90[AMR][1000 genomes];0.83[EUR][1000 genomes]
rs4929942	0.96[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs4929943	0.94[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs4929944	0.92[AMR][1000 genomes];0.85[EUR][1000 genomes]
rs4929945	0.92[AMR][1000 genomes];0.85[EUR][1000 genomes]
rs4929949	0.96[AMR][1000 genomes];0.83[EUR][1000 genomes]
rs6484485	0.94[AMR][1000 genomes];0.84[EUR][1000 genomes]
rs7934396	0.95[AMR][1000 genomes];0.83[EUR][1000 genomes]
rs7950870	0.81[AMR][1000 genomes]
rs9300090	0.87[AMR][1000 genomes];0.80[EUR][1000 genomes]
rs9300091	0.92[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs9705083	0.84[AMR][1000 genomes]
rs9705253	0.95[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs9736791	0.88[AMR][1000 genomes];0.81[EUR][1000 genomes]
rs9737312	0.84[AMR][1000 genomes]
rs9737401	0.90[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	esv2751035	chr11:8431654-8685451	Strong transcription Weak transcription Enhancers ZNF genes & repeats Genic enhancers Flanking Active TSS Bivalent/Poised TSS Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	8 gene(s)	inside rSNPs	diseases
2	nsv896983	chr11:8526643-8682465	ZNF genes & repeats Strong transcription Weak transcription Bivalent Enhancer Flanking Active TSS Enhancers Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA	8 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs12277932	STK33	cis	Artery Tibial	GTEx

Chromatin state (count:55 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:8623400-8634200	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
2	chr11:8623600-8632000	Weak transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
3	chr11:8626000-8637000	Weak transcription	Fetal Intestine Small	intestine
4	chr11:8626000-8637200	Weak transcription	Monocytes-CD14+_RO01746	blood
5	chr11:8626000-8661600	Weak transcription	ES-I3 Cell Line	embryonic stem cell
6	chr11:8626000-8661800	Weak transcription	HUES48 Cell Line	embryonic stem cell
7	chr11:8626200-8637200	Weak transcription	Primary monocytes fromperipheralblood	blood
8	chr11:8626200-8653000	Weak transcription	Rectal Smooth Muscle	rectum
9	chr11:8626400-8634000	Weak transcription	Placenta	Placenta
10	chr11:8626400-8634200	Weak transcription	Skeletal Muscle Female	skeletal muscle
11	chr11:8626400-8636000	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
12	chr11:8626400-8636200	Weak transcription	Stomach Smooth Muscle	stomach
13	chr11:8626400-8636800	Weak transcription	Sigmoid Colon	Sigmoid Colon
14	chr11:8626400-8637200	Weak transcription	Pancreas	Pancrea
15	chr11:8626400-8637400	Weak transcription	Adipose Nuclei	Adipose
16	chr11:8626400-8638400	Weak transcription	Duodenum Mucosa	Duodenum
17	chr11:8626400-8638400	Weak transcription	Duodenum Smooth Muscle	Duodenum
18	chr11:8626400-8643400	Weak transcription	Fetal Lung	lung
19	chr11:8626600-8637200	Weak transcription	Skeletal Muscle Male	skeletal muscle
20	chr11:8626600-8639600	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
21	chr11:8626600-8648800	Weak transcription	Stomach Mucosa	stomach
22	chr11:8626800-8637000	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
23	chr11:8626800-8637200	Weak transcription	Esophagus	oesophagus
24	chr11:8626800-8659600	Weak transcription	Hela-S3	cervix
25	chr11:8627600-8637200	Weak transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
26	chr11:8627800-8637000	Weak transcription	HMEC	breast
27	chr11:8627800-8637200	Weak transcription	NHEK	skin
28	chr11:8627800-8642400	Weak transcription	A549	lung
29	chr11:8628000-8635400	Weak transcription	Breast Myoepithelial Primary Cells	Breast
30	chr11:8628000-8637000	Weak transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
31	chr11:8628400-8634200	Weak transcription	HSMM	muscle
32	chr11:8628800-8637200	Weak transcription	Primary T cells from cord blood	blood
33	chr11:8629200-8638000	Weak transcription	Brain Cingulate Gyrus	brain
34	chr11:8629400-8635200	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
35	chr11:8630000-8634200	Weak transcription	Liver	Liver
36	chr11:8630200-8642400	Weak transcription	Ganglion Eminence derived primary cultured neurospheres	brain
37	chr11:8630400-8631800	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
38	chr11:8630400-8634200	Weak transcription	Aorta	Aorta
39	chr11:8630600-8633800	Weak transcription	Lung	lung
40	chr11:8630600-8635600	Weak transcription	IMR90 fetal lung fibroblasts Cell Line	lung
41	chr11:8630600-8653000	Weak transcription	Osteobl	bone
42	chr11:8630800-8632400	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
43	chr11:8630800-8633400	Weak transcription	HSMMtube	muscle
44	chr11:8630800-8634000	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
45	chr11:8630800-8634400	Weak transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
46	chr11:8630800-8637600	Weak transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
47	chr11:8630800-8638000	Weak transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
48	chr11:8630800-8638400	Weak transcription	Muscle Satellite Cultured Cells	--
49	chr11:8630800-8645400	Weak transcription	NHLF	lung
50	chr11:8630800-8645600	Weak transcription	NH-A	brain

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