Variant report

Variant	rs56253831
Chromosome Location	chr15:74752747-74752748
allele	A/C
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	RELA	chr15:74752633-74754618	GM18505	blood:	n/a	chr15:74753521-74753530 chr15:74753521-74753530
2	POLR2A	chr15:74752546-74754142	SK-N-MC	brain:	n/a	n/a
3	TAF1	chr15:74752608-74753021	GM12878	blood:	n/a	n/a
4	TBP	chr15:74752690-74754528	GM12878	blood:	n/a	n/a
5	TEAD4	chr15:74752688-74754689	K562	blood:	n/a	chr15:74754395-74754404
6	HCFC1	chr15:74752577-74755009	Hela-S3	cervix:	n/a	n/a
7	WRNIP1	chr15:74752681-74754007	GM12878	blood:	n/a	n/a
8	MAX	chr15:74752715-74754257	GM12878	blood:	n/a	chr15:74752933-74752943
9	POLR2A	chr15:74752657-74754599	GM12878	blood:	n/a	n/a
10	EP300	chr15:74752666-74753004	GM12878	blood:	n/a	chr15:74752803-74752817
11	RELA	chr15:74752603-74754516	GM12891	blood:	n/a	chr15:74753521-74753530 chr15:74753521-74753530
12	POLR2A	chr15:74752631-74752999	GM12892	blood:	n/a	n/a
13	SPI1	chr15:74752625-74753115	GM12878	blood:	n/a	n/a
14	CHD1	chr15:74752655-74754164	GM12878	blood:	n/a	n/a
15	MXI1	chr15:74752547-74754695	SK-N-SH	brain:	n/a	n/a
16	BATF	chr15:74752633-74752936	GM12878	blood:	n/a	n/a
17	POLR2A	chr15:74752578-74754536	GM12892	blood:	n/a	n/a
18	TBL1XR1	chr15:74752711-74754600	GM12878	blood:	n/a	n/a
19	EP300	chr15:74752695-74754495	GM12878	blood:	n/a	chr15:74752803-74752817
20	PML	chr15:74752553-74754437	GM12878	blood:	n/a	n/a
21	SPI1	chr15:74752648-74753000	GM12891	blood:	n/a	n/a
22	CUX1	chr15:74752730-74753748	GM12878	blood:	n/a	n/a
23	STAT5A	chr15:74752707-74753885	GM12878	blood:	n/a	n/a
24	MXI1	chr15:74752643-74754555	GM12878	blood:	n/a	n/a
25	POLR2A	chr15:74752586-74754640	GM12891	blood:	n/a	n/a
26	POLR2A	chr15:74752667-74752892	ProgFib	skin:	n/a	n/a
27	SPI1	chr15:74752637-74753017	GM12878	blood:	n/a	n/a
28	POLR2A	chr15:74752726-74753895	MCF10A-Er-Src	breast:	n/a	n/a
29	CHD2	chr15:74752738-74754171	GM12878	blood:	n/a	n/a
30	ATF2	chr15:74752676-74754344	GM12878	blood:	n/a	n/a
31	POLR2A	chr15:74752646-74754150	MCF10A-Er-Src	breast:	n/a	n/a
32	POLR2A	chr15:74752593-74754634	GM12878	blood:	n/a	n/a
33	SIN3A	chr15:74752745-74754109	GM12878	blood:	n/a	chr15:74753420-74753433 chr15:74753471-74753482
34	POLR2A	chr15:74752550-74754644	GM12878	blood:	n/a	n/a
35	BCLAF1	chr15:74752539-74754291	GM12878	blood:	n/a	chr15:74753566-74753575 chr15:74753466-74753479 chr15:74752803-74752812
36	NFIC	chr15:74752612-74754611	GM12878	blood:	n/a	n/a
37	BATF	chr15:74752597-74752946	GM12878	blood:	n/a	n/a
38	SPI1	chr15:74752583-74753015	GM12891	blood:	n/a	n/a
39	MAZ	chr15:74752677-74754028	GM12878	blood:	n/a	chr15:74752933-74752943
40	RUNX3	chr15:74752574-74754368	GM12878	blood:	n/a	n/a
41	STAT5A	chr15:74752645-74754538	GM12878	blood:	n/a	n/a
42	POLR2A	chr15:74752618-74752950	GM12891	blood:	n/a	n/a
43	POLR2A	chr15:74752630-74755148	IMR90	lung:	n/a	n/a
44	RELA	chr15:74752682-74754624	GM19193	blood:	n/a	chr15:74753521-74753530 chr15:74753521-74753530
45	POLR2A	chr15:74752721-74752793	HepG2	liver:	n/a	n/a
46	RELA	chr15:74752705-74754641	GM12878	blood:	n/a	chr15:74753521-74753530 chr15:74753521-74753530
47	RELA	chr15:74752734-74754657	GM10847	blood:	n/a	chr15:74753521-74753530 chr15:74753521-74753530
48	MTA3	chr15:74752424-74754820	GM12878	blood:	n/a	n/a
49	SPI1	chr15:74752604-74753047	HL-60	blood:	n/a	n/a
50	RUNX3	chr15:74752611-74754589	GM12878	blood:	n/a	n/a

No.	Distal block	Cell Line	Cell type
1	chr15:74740802..74742938-chr15:74751903..74754187,4	K562	blood:
2	chr15:74751132..74753039-chr20:50911439..50913832,2	MCF-7	breast:
3	chr15:74724949..74728351-chr15:74752030..74754909,4	K562	blood:
4	chr15:74749825..74755412-chr15:74831975..74836764,7	K562	blood:
5	chr15:74752565..74755217-chr15:74831873..74834547,2	MCF-7	breast:
6	chr15:74741955..74744869-chr15:74750008..74755464,5	K562	blood:
7	chr15:74751346..74753406-chr15:74872980..74874906,2	K562	blood:
8	chr15:74752377..74755555-chr15:74772398..74775932,4	MCF-7	breast:
9	chr15:74744211..74746229-chr15:74751385..74754144,2	MCF-7	breast:
10	chr15:74752041..74753655-chr15:74907402..74909986,3	K562	blood:
11	chr15:74751343..74754967-chr15:74831975..74835233,5	K562	blood:
12	chr15:74751774..74754602-chr15:74987400..74989019,2	K562	blood:
13	chr15:74751104..74753940-chr15:74907025..74909601,4	MCF-7	breast:

Variant related genes	Relation type
UBL7-AS1	TF binding region
ENSG00000138623	Chromatin interaction
ENSG00000179361	Chromatin interaction
ENSG00000138629	Chromatin interaction
ENSG00000260103	Chromatin interaction
ENSG00000179151	Chromatin interaction
ENSG00000260919	Chromatin interaction
ENSG00000179335	Chromatin interaction

Extended variants
information (count: 15 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:13)

rs_ID	r²[population]
rs11632086	0.97[AFR][1000 genomes]
rs11633697	0.97[AFR][1000 genomes]
rs11637129	0.90[AFR][1000 genomes]
rs17343071	0.92[AFR][1000 genomes]
rs28362873	0.81[AFR][1000 genomes]
rs28362914	0.88[AFR][1000 genomes]
rs55936349	0.97[AFR][1000 genomes]
rs57317343	0.95[AFR][1000 genomes]
rs57592570	0.97[AFR][1000 genomes]
rs74025808	0.92[AFR][1000 genomes]
rs74025809	0.95[AFR][1000 genomes]
rs74025810	1.00[AFR][1000 genomes]
rs74025811	0.97[AFR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv482615	chr15:74593625-74757962	Enhancers Active TSS Flanking Active TSS Flanking Bivalent TSS/Enh Weak transcription Strong transcription Bivalent Enhancer Genic enhancers Bivalent/Poised TSS Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	58 gene(s)	inside rSNPs	diseases
2	esv1809847	chr15:74734500-74948063	Genic enhancers Flanking Active TSS Weak transcription Active TSS Flanking Bivalent TSS/Enh Bivalent Enhancer Strong transcription Enhancers Transcr. at gene 5' and 3' Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	70 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:125 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr15:74726800-74752800	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
2	chr15:74743600-74753000	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
3	chr15:74744800-74753000	Weak transcription	Esophagus	oesophagus
4	chr15:74745000-74753000	Weak transcription	Aorta	Aorta
5	chr15:74746600-74752800	Weak transcription	Pancreatic Islets	Pancreatic Islet
6	chr15:74748000-74752800	Weak transcription	Sigmoid Colon	Sigmoid Colon
7	chr15:74749400-74752800	Weak transcription	Ovary	ovary
8	chr15:74749400-74752800	Weak transcription	Pancreas	Pancrea
9	chr15:74749600-74753200	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
10	chr15:74751200-74752800	Weak transcription	Primary T cells effector/memory enriched fromperipheralblood	blood
11	chr15:74752000-74752800	Enhancers	H1 Derived Mesenchymal Stem Cells	ES cell derived
12	chr15:74752000-74752800	Enhancers	Primary T helper memory cells from peripheral blood 1	blood
13	chr15:74752000-74752800	Enhancers	Right Ventricle	heart
14	chr15:74752000-74753000	Enhancers	Small Intestine	intestine
15	chr15:74752200-74752800	Enhancers	Primary Natural Killer cells fromperipheralblood	blood
16	chr15:74752400-74752800	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
17	chr15:74752400-74752800	Enhancers	Primary monocytes fromperipheralblood	blood
18	chr15:74752400-74752800	Enhancers	Primary neutrophils fromperipheralblood	blood
19	chr15:74752400-74752800	Enhancers	Primary T helper 17 cells PMA-I stimulated	--
20	chr15:74752400-74752800	Enhancers	Fetal Brain Male	brain
21	chr15:74752400-74752800	Enhancers	Placenta	Placenta
22	chr15:74752400-74753000	Flanking Active TSS	Primary B cells from peripheral blood	blood
23	chr15:74752400-74753000	Flanking Active TSS	Ganglion Eminence derived primary cultured neurospheres	brain
24	chr15:74752400-74753000	Flanking Active TSS	Skeletal Muscle Female	skeletal muscle
25	chr15:74752400-74753200	Flanking Active TSS	Breast Myoepithelial Primary Cells	Breast
26	chr15:74752400-74753200	Flanking Active TSS	Brain Germinal Matrix	brain
27	chr15:74752400-74753400	Flanking Active TSS	Primary T helper cells fromperipheralblood	blood
28	chr15:74752400-74753400	Flanking Active TSS	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
29	chr15:74752400-74753400	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Female	--
30	chr15:74752400-74753400	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Male	--
31	chr15:74752400-74754200	Active TSS	Foreskin Fibroblast Primary Cells skin01	Skin
32	chr15:74752600-74752800	Flanking Active TSS	H1 Cell Line	embryonic stem cell
33	chr15:74752600-74752800	Flanking Active TSS	HUES64 Cell Line	embryonic stem cell
34	chr15:74752600-74752800	Flanking Active TSS	iPS-18 Cell Line	embryonic stem cell
35	chr15:74752600-74752800	Flanking Active TSS	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
36	chr15:74752600-74752800	Flanking Active TSS	Foreskin Melanocyte Primary Cells skin03	Skin
37	chr15:74752600-74752800	Enhancers	Primary mononuclear cells fromperipheralblood	Blood
38	chr15:74752600-74752800	Active TSS	Fetal Kidney	kidney
39	chr15:74752600-74752800	Flanking Active TSS	Fetal Muscle Trunk	muscle
40	chr15:74752600-74752800	Enhancers	Gastric	stomach
41	chr15:74752600-74752800	Weak transcription	Left Ventricle	heart
42	chr15:74752600-74752800	Enhancers	Lung	lung
43	chr15:74752600-74752800	Enhancers	Right Atrium	heart
44	chr15:74752600-74752800	Enhancers	Stomach Mucosa	stomach
45	chr15:74752600-74752800	Enhancers	Spleen	Spleen
46	chr15:74752600-74752800	Flanking Active TSS	K562	blood
47	chr15:74752600-74752800	Flanking Active TSS	NHDF-Ad	bronchial
48	chr15:74752600-74752800	Flanking Active TSS	NHLF	lung
49	chr15:74752600-74753000	Flanking Active TSS	iPS-20b Cell Line	embryonic stem cell
50	chr15:74752600-74753000	Flanking Active TSS	Primary T helper memory cells from peripheral blood 2	blood

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links