Variant report

Variant	rs6907247
Chromosome Location	chr6:76390937-76390938
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr6:76363284..76364897-chr6:76389536..76391998,2	MCF-7	breast:

Extended variants
information (count: 76 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:49)

rs_ID	r²[population]
rs1018103	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs10943273	0.82[EUR][1000 genomes]
rs12524436	0.80[EUR][1000 genomes]
rs12525161	0.82[EUR][1000 genomes]
rs13191639	0.82[EUR][1000 genomes]
rs13214795	0.87[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs2133192	0.98[AFR][1000 genomes];0.93[AMR][1000 genomes];0.99[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs2647399	0.90[AMR][1000 genomes];0.89[EUR][1000 genomes]
rs2647401	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2647402	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2647403	0.87[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs2647409	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2647412	0.81[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs2647413	0.83[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2647415	0.95[AFR][1000 genomes];0.98[AMR][1000 genomes];0.99[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs2647416	0.85[AFR][1000 genomes];1.00[AMR][1000 genomes];0.96[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs2647418	0.90[AMR][1000 genomes];0.89[EUR][1000 genomes]
rs2647419	0.90[AMR][1000 genomes];0.89[EUR][1000 genomes]
rs2748953	0.81[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2748965	0.80[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs2783351	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2784730	0.86[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2784732	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2784733	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2842535	0.90[AMR][1000 genomes];0.89[EUR][1000 genomes]
rs2842539	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2842563	0.81[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs2842571	0.83[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs2842572	0.82[AMR][1000 genomes];0.85[EUR][1000 genomes]
rs34239015	0.82[EUR][1000 genomes]
rs478934	0.90[AFR][1000 genomes];0.82[AMR][1000 genomes];0.87[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs486777	0.82[ASN][1000 genomes]
rs570939	0.91[AFR][1000 genomes];0.98[AMR][1000 genomes];0.98[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs575720	0.88[AFR][1000 genomes];0.84[AMR][1000 genomes];0.90[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs6453832	0.81[AFR][1000 genomes];0.80[EUR][1000 genomes]
rs649935	0.87[AFR][1000 genomes];0.84[AMR][1000 genomes];0.90[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs6911868	0.83[AFR][1000 genomes];0.85[EUR][1000 genomes]
rs6936251	0.83[AFR][1000 genomes];0.85[EUR][1000 genomes]
rs6936565	0.97[AFR][1000 genomes];0.86[AMR][1000 genomes];0.97[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs7356806	0.83[EUR][1000 genomes]
rs7747801	0.81[EUR][1000 genomes]
rs775071	0.95[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs9294001	0.83[EUR][1000 genomes]
rs9350598	0.93[AFR][1000 genomes];0.93[AMR][1000 genomes];0.98[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs9352237	0.97[AFR][1000 genomes];0.93[AMR][1000 genomes];1.00[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs9352238	0.98[AFR][1000 genomes];0.93[AMR][1000 genomes];0.99[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs9359137	0.95[AFR][1000 genomes];0.91[AMR][1000 genomes];0.99[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs9447522	0.80[EUR][1000 genomes]
rs9447524	0.82[EUR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:27 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1027915	chr6:75893542-76510113	Active TSS Enhancers Strong transcription Bivalent Enhancer Weak transcription Flanking Bivalent TSS/Enh Flanking Active TSS Genic enhancers ZNF genes & repeats Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	70 gene(s)	inside rSNPs	diseases
2	nsv538311	chr6:75893542-76510113	Weak transcription Enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Active TSS Strong transcription Bivalent/Poised TSS Genic enhancers Bivalent Enhancer ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	70 gene(s)	inside rSNPs	diseases
3	nsv1022428	chr6:76023118-76575620	Weak transcription Strong transcription Enhancers Flanking Active TSS Active TSS Genic enhancers ZNF genes & repeats Bivalent/Poised TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA	48 gene(s)	inside rSNPs	diseases
4	nsv538312	chr6:76023118-76575620	Weak transcription Enhancers Bivalent Enhancer Flanking Active TSS Strong transcription Transcr. at gene 5' and 3' Active TSS Genic enhancers Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	48 gene(s)	inside rSNPs	diseases
5	nsv1032245	chr6:76045537-76545703	Enhancers Weak transcription Strong transcription Flanking Active TSS Active TSS ZNF genes & repeats Bivalent/Poised TSS Genic enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA	47 gene(s)	inside rSNPs	diseases
6	nsv538313	chr6:76045537-76545703	Strong transcription Weak transcription Enhancers Active TSS Bivalent/Poised TSS Flanking Active TSS ZNF genes & repeats Genic enhancers Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA miRNA	47 gene(s)	inside rSNPs	diseases
7	nsv1019328	chr6:76154751-76604197	Enhancers Weak transcription Strong transcription Active TSS Bivalent/Poised TSS Flanking Active TSS Genic enhancers ZNF genes & repeats Bivalent Enhancer Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	44 gene(s)	inside rSNPs	diseases
8	nsv538314	chr6:76154751-76604197	Enhancers Strong transcription Active TSS Weak transcription Genic enhancers Flanking Active TSS ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent/Poised TSS Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	44 gene(s)	inside rSNPs	diseases
9	nsv1023331	chr6:76238459-76482117	Strong transcription ZNF genes & repeats Active TSS Weak transcription Flanking Active TSS Enhancers Genic enhancers Flanking Bivalent TSS/Enh Bivalent/Poised TSS Transcr. at gene 5' and 3' Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	38 gene(s)	inside rSNPs	diseases
10	nsv538315	chr6:76238459-76482117	Enhancers Strong transcription Flanking Active TSS Weak transcription Active TSS Flanking Bivalent TSS/Enh Genic enhancers Bivalent/Poised TSS Bivalent Enhancer Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	38 gene(s)	inside rSNPs	diseases
11	nsv1017542	chr6:76238459-76537447	Strong transcription Weak transcription Enhancers Active TSS Flanking Bivalent TSS/Enh Flanking Active TSS ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3' Bivalent Enhancer Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	38 gene(s)	inside rSNPs	diseases
12	nsv1031745	chr6:76257913-76493355	Enhancers Weak transcription Flanking Active TSS Bivalent/Poised TSS Strong transcription Active TSS Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	38 gene(s)	inside rSNPs	diseases
13	nsv538316	chr6:76257913-76493355	Strong transcription Enhancers Weak transcription Flanking Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Active TSS Bivalent Enhancer Genic enhancers ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	38 gene(s)	inside rSNPs	diseases
14	nsv533100	chr6:76257914-76493354	Enhancers Weak transcription Strong transcription Genic enhancers Active TSS Flanking Active TSS Bivalent/Poised TSS ZNF genes & repeats Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	38 gene(s)	inside rSNPs	diseases
15	nsv1023749	chr6:76287578-76482117	Weak transcription Flanking Active TSS Genic enhancers Strong transcription Enhancers Active TSS Transcr. at gene 5' and 3' ZNF genes & repeats Bivalent/Poised TSS Flanking Bivalent TSS/Enh Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	38 gene(s)	inside rSNPs	diseases
16	nsv538317	chr6:76287578-76482117	Strong transcription Weak transcription Active TSS Enhancers Flanking Active TSS Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	38 gene(s)	inside rSNPs	diseases
17	nsv1021090	chr6:76306100-76759397	Weak transcription Enhancers Active TSS Strong transcription Flanking Bivalent TSS/Enh Flanking Active TSS Genic enhancers Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	40 gene(s)	inside rSNPs	diseases
18	nsv538318	chr6:76306100-76759397	Flanking Active TSS Enhancers Weak transcription ZNF genes & repeats Bivalent/Poised TSS Active TSS Strong transcription Genic enhancers Flanking Bivalent TSS/Enh Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	40 gene(s)	inside rSNPs	diseases
19	nsv886183	chr6:76320846-76399539	Strong transcription Enhancers Weak transcription Genic enhancers ZNF genes & repeats Flanking Active TSS Active TSS	TF binding region CpG island Chromatin interactive region lncRNA	11 gene(s)	inside rSNPs	diseases
20	nsv886184	chr6:76320846-76462711	Weak transcription Strong transcription Flanking Active TSS Enhancers Genic enhancers ZNF genes & repeats Flanking Bivalent TSS/Enh Active TSS Bivalent/Poised TSS Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	21 gene(s)	inside rSNPs	diseases
21	nsv886185	chr6:76320846-76498109	Weak transcription Strong transcription Flanking Active TSS Enhancers ZNF genes & repeats Active TSS Bivalent/Poised TSS Genic enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	21 gene(s)	inside rSNPs	diseases
22	nsv886186	chr6:76328955-76469115	Active TSS Flanking Bivalent TSS/Enh Weak transcription Strong transcription Enhancers Flanking Active TSS Bivalent/Poised TSS ZNF genes & repeats Bivalent Enhancer Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	21 gene(s)	inside rSNPs	diseases
23	nsv1032961	chr6:76343575-76788852	Strong transcription Weak transcription Enhancers Flanking Active TSS Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Genic enhancers ZNF genes & repeats Transcr. at gene 5' and 3' Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	22 gene(s)	inside rSNPs	diseases
24	nsv932201	chr6:76365548-77219650	Enhancers Weak transcription Strong transcription Flanking Active TSS Flanking Bivalent TSS/Enh Active TSS ZNF genes & repeats Bivalent Enhancer Genic enhancers Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	20 gene(s)	inside rSNPs	diseases
25	nsv522814	chr6:76375321-76405700	ZNF genes & repeats Weak transcription Strong transcription Genic enhancers Enhancers Active TSS Flanking Active TSS	TF binding region Chromatin interactive region	2 gene(s)	inside rSNPs	diseases
26	esv3335869	chr6:76389281-76411862	Weak transcription Strong transcription Enhancers ZNF genes & repeats Genic enhancers Flanking Active TSS Active TSS	Chromatin interactive region	3 gene(s)	inside rSNPs	diseases
27	esv3332890	chr6:76390281-76414581	Weak transcription Strong transcription Genic enhancers ZNF genes & repeats Enhancers Active TSS Flanking Active TSS	Chromatin interactive region	2 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs6907247	SENP6	cis	Whole Blood	GTEx

Chromatin state (count:125 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr6:76320200-76391600	Weak transcription	ES-WA7 Cell Line	embryonic stem cell
2	chr6:76333200-76391000	Strong transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
3	chr6:76339400-76402000	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
4	chr6:76342800-76391200	Strong transcription	Primary hematopoietic stem cells short term culture	blood
5	chr6:76354600-76391200	Strong transcription	HUES64 Cell Line	embryonic stem cell
6	chr6:76356800-76391800	Strong transcription	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
7	chr6:76358200-76392200	Strong transcription	Primary T helper cells PMA-I stimulated	--
8	chr6:76358400-76391000	Strong transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
9	chr6:76364400-76392200	Strong transcription	HUES48 Cell Line	embryonic stem cell
10	chr6:76364800-76392400	Strong transcription	HUES6 Cell Line	embryonic stem cell
11	chr6:76366400-76392400	Strong transcription	Primary T helper cells fromperipheralblood	blood
12	chr6:76366600-76392400	Strong transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
13	chr6:76366800-76391000	Strong transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
14	chr6:76368200-76392200	Strong transcription	Monocytes-CD14+_RO01746	blood
15	chr6:76368600-76391800	Strong transcription	Fetal Lung	lung
16	chr6:76368800-76392000	Strong transcription	Primary T regulatory cells fromperipheralblood	blood
17	chr6:76370200-76391800	Weak transcription	Fetal Heart	heart
18	chr6:76376000-76391200	Strong transcription	Breast Myoepithelial Primary Cells	Breast
19	chr6:76376000-76393000	Strong transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
20	chr6:76379400-76392200	Strong transcription	Primary Natural Killer cells fromperipheralblood	blood
21	chr6:76379600-76392200	Strong transcription	Dnd41	blood
22	chr6:76380000-76393000	Strong transcription	Primary monocytes fromperipheralblood	blood
23	chr6:76382000-76422800	Weak transcription	Stomach Mucosa	stomach
24	chr6:76383000-76392400	Strong transcription	ES-UCSF4 Cell Line	embryonic stem cell
25	chr6:76383000-76392400	Strong transcription	Foreskin Melanocyte Primary Cells skin03	Skin
26	chr6:76383000-76393000	Strong transcription	Primary T cells fromperipheralblood	blood
27	chr6:76383000-76393000	Strong transcription	Foreskin Keratinocyte Primary Cells skin03	Skin
28	chr6:76383200-76392200	Strong transcription	Stomach Smooth Muscle	stomach
29	chr6:76383200-76393000	Strong transcription	Primary neutrophils fromperipheralblood	blood
30	chr6:76383400-76392200	Strong transcription	Duodenum Mucosa	Duodenum
31	chr6:76383400-76392200	Strong transcription	Osteobl	bone
32	chr6:76383400-76392400	Strong transcription	Primary hematopoietic stem cells	blood
33	chr6:76383400-76392400	Strong transcription	Adipose Nuclei	Adipose
34	chr6:76383400-76393200	Strong transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
35	chr6:76383600-76392200	Strong transcription	Placenta	Placenta
36	chr6:76383600-76392400	Strong transcription	Liver	Liver
37	chr6:76383800-76392400	Strong transcription	iPS-18 Cell Line	embryonic stem cell
38	chr6:76383800-76397000	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
39	chr6:76384200-76392400	Strong transcription	Muscle Satellite Cultured Cells	--
40	chr6:76384600-76393000	Strong transcription	Rectal Mucosa Donor 29	rectum
41	chr6:76384800-76392200	Strong transcription	Primary B cells from peripheral blood	blood
42	chr6:76385200-76392200	Strong transcription	Rectal Mucosa Donor 31	rectum
43	chr6:76385200-76392400	Strong transcription	Primary T cells effector/memory enriched fromperipheralblood	blood
44	chr6:76385400-76391800	Strong transcription	Fetal Intestine Large	intestine
45	chr6:76385400-76392000	Strong transcription	Duodenum Smooth Muscle	Duodenum
46	chr6:76385400-76392000	Strong transcription	HepG2	liver
47	chr6:76385400-76392200	Strong transcription	HSMM	muscle
48	chr6:76385400-76392800	Strong transcription	Fetal Thymus	thymus
49	chr6:76385400-76393000	Strong transcription	H1 Cell Line	embryonic stem cell
50	chr6:76385600-76391800	Strong transcription	Primary mononuclear cells fromperipheralblood	Blood

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