Variant report

Variant	rs2851073
Chromosome Location	chr11:74867043-74867044
allele	C/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:44)
CpG islands
(count:0)
Chromatin interactive
region (count:4)
LncRNA
region (count:0)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:44 , 50 per page) page: 1

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	MAFK	chr11:74867004-74867502	HepG2	liver:	n/a	n/a
2	TCF12	chr11:74866986-74867584	A549	lung:	n/a	n/a
3	EP300	chr11:74866993-74867507	HepG2	liver:	n/a	n/a
4	HNF4G	chr11:74866831-74867483	HepG2	liver:	n/a	n/a
5	POLR2A	chr11:74866927-74867540	K562	blood:	n/a	n/a
6	NR2F2	chr11:74866864-74867584	HepG2	liver:	n/a	n/a
7	CTCF	chr11:74866960-74867110	Caco-2	colon:	n/a	n/a
8	FOXA2	chr11:74866868-74867496	HepG2	liver:	n/a	n/a
9	TEAD4	chr11:74866629-74867560	HepG2	liver:	n/a	n/a
10	ZBTB7A	chr11:74866877-74867213	HepG2	liver:	n/a	n/a
11	HNF4A	chr11:74866858-74867452	HepG2	liver:	n/a	n/a
12	MBD4	chr11:74866862-74867489	HepG2	liver:	n/a	n/a
13	MYBL2	chr11:74866587-74867557	HepG2	liver:	n/a	n/a
14	NFIC	chr11:74866930-74867516	HepG2	liver:	n/a	n/a
15	RAD21	chr11:74866911-74867465	HepG2	liver:	n/a	n/a
16	HEY1	chr11:74866835-74867529	HepG2	liver:	n/a	n/a
17	HDAC2	chr11:74866904-74867511	HepG2	liver:	n/a	chr11:74867349-74867358
18	RXRA	chr11:74866795-74867384	HepG2	liver:	n/a	n/a
19	MBD4	chr11:74866753-74867523	HepG2	liver:	n/a	n/a
20	RAD21	chr11:74866952-74867496	HepG2	liver:	n/a	n/a
21	SP1	chr11:74866742-74867535	HepG2	liver:	n/a	n/a
22	POLR2A	chr11:74866886-74867210	HepG2	liver:	n/a	n/a
23	FOXA1	chr11:74866879-74867473	HepG2	liver:	n/a	n/a
24	NR2F2	chr11:74866680-74867712	HepG2	liver:	n/a	n/a
25	FOXA1	chr11:74866800-74867569	HepG2	liver:	n/a	n/a
26	FOXA1	chr11:74866738-74867487	HepG2	liver:	n/a	n/a
27	HNF4A	chr11:74866945-74867464	HepG2	liver:	n/a	n/a
28	HEY1	chr11:74867006-74867478	HepG2	liver:	n/a	n/a
29	HNF4A	chr11:74866874-74867503	HepG2	liver:	n/a	n/a
30	MAFF	chr11:74867037-74867538	HepG2	liver:	n/a	n/a
31	FOXA2	chr11:74867010-74867480	A549	lung:	n/a	n/a
32	EP300	chr11:74866755-74867512	HepG2	liver:	n/a	n/a
33	MAX	chr11:74866598-74867648	HepG2	liver:	n/a	n/a
34	FOXA1	chr11:74866835-74867447	HepG2	liver:	n/a	n/a
35	NR2F2	chr11:74866949-74867519	MCF-7	breast:	n/a	n/a
36	EP300	chr11:74866925-74867533	HepG2	liver:	n/a	n/a
37	NFIC	chr11:74866854-74867556	HepG2	liver:	n/a	n/a
38	HNF4G	chr11:74866765-74867485	HepG2	liver:	n/a	n/a
39	MYBL2	chr11:74866681-74867566	HepG2	liver:	n/a	n/a
40	TCF12	chr11:74866986-74867456	HepG2	liver:	n/a	n/a
41	HDAC2	chr11:74866707-74867490	HepG2	liver:	n/a	chr11:74867349-74867358
42	ARID3A	chr11:74866852-74867509	HepG2	liver:	n/a	n/a
43	POLR2A	chr11:74866964-74867484	HepG2	liver:	n/a	n/a
44	RCOR1	chr11:74866947-74867139	HepG2	liver:	n/a	n/a

No data

(count:4 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr11:74864381..74867462-chr11:74869783..74873226,3	MCF-7	breast:
2	chr11:74860782..74862620-chr11:74866728..74869676,2	MCF-7	breast:
3	chr11:74866771..74870278-chr11:74874697..74878251,4	K562	blood:
4	chr11:74860426..74862138-chr11:74866873..74869626,2	K562	blood:

No data

Variant related genes	Relation type
SLCO2B1	TF binding region
ENSG00000137491	Chromatin interaction

Extended variants
information (count: 18 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:17)

rs_ID	r²[population]
rs11236359	0.85[AFR][1000 genomes];0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs2187435	0.95[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs2712781	0.81[EUR][1000 genomes]
rs2712805	0.95[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs2712807	0.97[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs2712810	0.97[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs2712819	0.98[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs2712820	0.89[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs2712821	0.80[AMR][1000 genomes];0.99[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2851064	0.94[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs2851066	0.97[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs2851074	0.81[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs2851094	0.86[EUR][1000 genomes]
rs2851096	0.86[EUR][1000 genomes]
rs2851102	0.92[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs2851110	0.86[ASN][1000 genomes]
rs753171	0.84[EUR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:1 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv897919	chr11:74862391-74875501	Flanking Active TSS Weak transcription Enhancers Genic enhancers Bivalent Enhancer Active TSS Bivalent/Poised TSS Flanking Bivalent TSS/Enh Strong transcription Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	1 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs2851073	XRRA1	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:46 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:74861200-74868400	Active TSS	Brain Hippocampus Middle	brain
2	chr11:74861600-74867200	Active TSS	Brain Cingulate Gyrus	brain
3	chr11:74863600-74885600	Weak transcription	Colon Smooth Muscle	Colon
4	chr11:74864200-74898400	Weak transcription	Esophagus	oesophagus
5	chr11:74864800-74868600	Enhancers	Pancreas	Pancrea
6	chr11:74864800-74870400	Enhancers	Fetal Intestine Large	intestine
7	chr11:74865000-74872000	Enhancers	Placenta	Placenta
8	chr11:74865400-74867600	Enhancers	Adipose Nuclei	Adipose
9	chr11:74865400-74867600	Enhancers	Fetal Muscle Trunk	muscle
10	chr11:74865400-74867600	Enhancers	Right Ventricle	heart
11	chr11:74865400-74868000	Enhancers	Fetal Muscle Leg	muscle
12	chr11:74865400-74868200	Enhancers	Sigmoid Colon	Sigmoid Colon
13	chr11:74865400-74868200	Enhancers	Stomach Mucosa	stomach
14	chr11:74865400-74868600	Enhancers	Fetal Stomach	stomach
15	chr11:74865400-74868800	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
16	chr11:74865400-74868800	Enhancers	Fetal Adrenal Gland	Adrenal Gland
17	chr11:74866000-74867400	Enhancers	Duodenum Smooth Muscle	Duodenum
18	chr11:74866000-74869000	Enhancers	Rectal Mucosa Donor 31	rectum
19	chr11:74866000-74869600	Weak transcription	Brain Substantia Nigra	brain
20	chr11:74866200-74867600	Enhancers	H1 Derived Mesenchymal Stem Cells	ES cell derived
21	chr11:74866200-74867600	Enhancers	Gastric	stomach
22	chr11:74866200-74867600	Enhancers	Lung	lung
23	chr11:74866200-74873000	Weak transcription	Brain Dorsolateral Prefrontal Cortex	brain
24	chr11:74866400-74867200	Weak transcription	Ovary	ovary
25	chr11:74866400-74867200	Weak transcription	Right Atrium	heart
26	chr11:74866400-74867600	Enhancers	Stomach Smooth Muscle	stomach
27	chr11:74866400-74868000	Weak transcription	Small Intestine	intestine
28	chr11:74866400-74869400	Enhancers	Fetal Intestine Small	intestine
29	chr11:74866400-74869600	Weak transcription	Skeletal Muscle Male	skeletal muscle
30	chr11:74866400-74870000	Weak transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
31	chr11:74866400-74871000	Weak transcription	Spleen	Spleen
32	chr11:74866400-74873000	Weak transcription	Fetal Thymus	thymus
33	chr11:74866800-74867200	Active TSS	Brain Anterior Caudate	brain
34	chr11:74866800-74867200	Weak transcription	Skeletal Muscle Female	skeletal muscle
35	chr11:74866800-74867400	Enhancers	A549	lung
36	chr11:74866800-74867600	Flanking Active TSS	Duodenum Mucosa	Duodenum
37	chr11:74866800-74867600	Flanking Active TSS	Rectal Mucosa Donor 29	rectum
38	chr11:74866800-74867600	Enhancers	K562	blood
39	chr11:74866800-74870400	Weak transcription	Left Ventricle	heart
40	chr11:74867000-74867200	Flanking Active TSS	Liver	Liver
41	chr11:74867000-74867400	Bivalent Enhancer	IMR90 fetal lung fibroblasts Cell Line	lung
42	chr11:74867000-74867400	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
43	chr11:74867000-74867600	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
44	chr11:74867000-74867600	Active TSS	Rectal Smooth Muscle	rectum
45	chr11:74867000-74867800	Flanking Active TSS	HepG2	liver
46	chr11:74867000-74869000	Enhancers	Colonic Mucosa	Colon

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