Variant report

Variant	rs28637653
Chromosome Location	chr11:74694715-74694716
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:27)
CpG islands
(count:0)
Chromatin interactive
region (count:5)
LncRNA
region (count:1)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:27 , 50 per page) page: 1

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	POLR2A	chr11:74694446-74694725	MCF-7	breast:	n/a	n/a
2	GATA2	chr11:74694478-74694827	HUVEC	blood vessel:	n/a	n/a
3	POLR2A	chr11:74694241-74695586	PANC-1	pancreas:	n/a	n/a
4	POLR2A	chr11:74694219-74695025	SK-N-MC	brain:	n/a	n/a
5	POLR2A	chr11:74694579-74694738	Hela-S3	cervix:	n/a	n/a
6	ZC3H11A	chr11:74694599-74694885	K562	blood:	n/a	n/a
7	POLR2A	chr11:74694514-74694826	GM12891	blood:	n/a	n/a
8	POLR2A	chr11:74694412-74695066	PFSK-1	brain:	n/a	n/a
9	POLR2A	chr11:74694395-74694964	GM12878	blood:	n/a	n/a
10	POLR2A	chr11:74694565-74694931	GM12878	blood:	n/a	n/a
11	NFATC1	chr11:74694631-74695063	GM12878	blood:	n/a	n/a
12	POLR2A	chr11:74694394-74696167	GM12878	blood:	n/a	n/a
13	POLR2A	chr11:74694336-74694883	GM12892	blood:	n/a	n/a
14	POLR2A	chr11:74694558-74695039	GM12891	blood:	n/a	n/a
15	POLR2A	chr11:74692891-74694741	HepG2	liver:	n/a	n/a
16	POLR2A	chr11:74694369-74694884	K562	blood:	n/a	n/a
17	POLR2A	chr11:74694594-74694859	Hela-S3	cervix:	n/a	n/a
18	SPI1	chr11:74694695-74694872	K562	blood:	n/a	n/a
19	NFATC1	chr11:74694420-74694788	GM12878	blood:	n/a	n/a
20	POLR2A	chr11:74691524-74696389	GM12878	blood:	n/a	n/a
21	POLR2A	chr11:74690426-74697517	K562	blood:	n/a	n/a
22	MAFK	chr11:74694621-74694719	K562	blood:	n/a	n/a
23	CUX1	chr11:74694535-74694893	K562	blood:	n/a	n/a
24	POLR2A	chr11:74694577-74694956	Hela-S3	cervix:	n/a	n/a
25	POLR2A	chr11:74690814-74696271	GM12891	blood:	n/a	n/a
26	POLR2A	chr11:74694467-74694986	GM12892	blood:	n/a	n/a
27	POLR2A	chr11:74694351-74694992	K562	blood:	n/a	n/a

No data

(count:5 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr11:74692366..74695026-chr11:74708015..74709624,2	K562	blood:
2	chr11:74668433..74670131-chr11:74694358..74696257,2	MCF-7	breast:
3	chr11:74659270..74662951-chr11:74693468..74696338,4	MCF-7	breast:
4	chr11:74680895..74682724-chr11:74692938..74695695,2	K562	blood:
5	chr11:74692434..74697441-chr11:74698257..74701616,5	MCF-7	breast:

(count:1 , 50 per page) page: 1

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-SPCS2-1	chr11:74693547-74695088	ENSG00000249164

No data

Variant related genes	Relation type
NEU3	TF binding region
ENSG00000166435	Chromatin interaction
ENSG00000118363	Chromatin interaction
ENSG00000162139	Chromatin interaction

Extended variants
information (count: 25 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:23)

rs_ID	r²[population]
rs10160407	0.85[AMR][1000 genomes]
rs11236249	0.85[AMR][1000 genomes]
rs11236259	0.85[AMR][1000 genomes]
rs11501910	0.85[AMR][1000 genomes]
rs12098929	0.85[AMR][1000 genomes];0.83[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12271960	0.80[EUR][1000 genomes]
rs12274227	0.85[AMR][1000 genomes]
rs12278314	0.85[AMR][1000 genomes]
rs12283412	0.85[AMR][1000 genomes]
rs12284331	0.85[AMR][1000 genomes]
rs12286425	0.85[AMR][1000 genomes]
rs12286482	0.85[AMR][1000 genomes]
rs12287287	0.85[AMR][1000 genomes]
rs12288052	0.85[AMR][1000 genomes]
rs13343191	0.85[AMR][1000 genomes];0.83[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4133526	0.85[AMR][1000 genomes]
rs57031821	0.85[AMR][1000 genomes]
rs73492727	0.85[AMR][1000 genomes]
rs73492743	0.85[AMR][1000 genomes]
rs73492794	0.85[AMR][1000 genomes]
rs73496929	0.85[AMR][1000 genomes]
rs73496931	0.85[AMR][1000 genomes]
rs7928010	0.85[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv832210	chr11:74562782-74732133	Weak transcription Enhancers Strong transcription Active TSS ZNF genes & repeats Genic enhancers Flanking Active TSS Transcr. at gene 5' and 3' Bivalent Enhancer Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	16 gene(s)	inside rSNPs	diseases
2	nsv975852	chr11:74693028-74696165	Weak transcription Enhancers Strong transcription	TF binding region Chromatin interactive region lncRNA	6 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:120 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:74661800-74699200	Weak transcription	H9 Cell Line	embryonic stem cell
2	chr11:74661800-74699400	Weak transcription	ES-I3 Cell Line	embryonic stem cell
3	chr11:74662200-74699600	Weak transcription	Esophagus	oesophagus
4	chr11:74675600-74699400	Weak transcription	Pancreatic Islets	Pancreatic Islet
5	chr11:74678600-74699200	Weak transcription	Spleen	Spleen
6	chr11:74681000-74699200	Weak transcription	iPS-15b Cell Line	embryonic stem cell
7	chr11:74681200-74699600	Weak transcription	Placenta Amnion	Placenta Amnion
8	chr11:74684400-74699200	Weak transcription	Pancreas	Pancrea
9	chr11:74684800-74699200	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
10	chr11:74686400-74699400	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
11	chr11:74686800-74699200	Weak transcription	Aorta	Aorta
12	chr11:74686800-74699400	Weak transcription	Fetal Brain Male	brain
13	chr11:74687200-74699200	Weak transcription	Right Ventricle	heart
14	chr11:74687600-74699600	Weak transcription	NHEK	skin
15	chr11:74687800-74699600	Weak transcription	Colon Smooth Muscle	Colon
16	chr11:74687800-74700000	Weak transcription	Fetal Heart	heart
17	chr11:74689200-74695000	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
18	chr11:74689400-74699200	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
19	chr11:74689400-74699200	Weak transcription	Muscle Satellite Cultured Cells	--
20	chr11:74689400-74699200	Weak transcription	Hela-S3	cervix
21	chr11:74689400-74699200	Weak transcription	HUVEC	blood vessel
22	chr11:74689400-74699400	Weak transcription	Brain Anterior Caudate	brain
23	chr11:74689400-74699400	Weak transcription	Rectal Smooth Muscle	rectum
24	chr11:74689400-74699600	Weak transcription	Brain Hippocampus Middle	brain
25	chr11:74689600-74699000	Weak transcription	Primary T helper memory cells from peripheral blood 2	blood
26	chr11:74689600-74699200	Weak transcription	Primary B cells from cord blood	blood
27	chr11:74689600-74699200	Weak transcription	Primary T helper memory cells from peripheral blood 1	blood
28	chr11:74689600-74699200	Weak transcription	Primary T regulatory cells fromperipheralblood	blood
29	chr11:74689600-74699200	Weak transcription	Primary T killer naive cells fromperipheralblood	blood
30	chr11:74689600-74699200	Weak transcription	Primary T killer memory cells from peripheral blood	blood
31	chr11:74689600-74699200	Weak transcription	Brain Inferior Temporal Lobe	brain
32	chr11:74689600-74699400	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
33	chr11:74689600-74699400	Weak transcription	Brain Cingulate Gyrus	brain
34	chr11:74689600-74699400	Weak transcription	NHLF	lung
35	chr11:74689600-74699600	Weak transcription	Brain Substantia Nigra	brain
36	chr11:74689800-74699200	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
37	chr11:74689800-74699200	Weak transcription	Colonic Mucosa	Colon
38	chr11:74690000-74699000	Weak transcription	Primary T helper naive cells from peripheral blood	blood
39	chr11:74690000-74699200	Weak transcription	Primary T helper naive cells fromperipheralblood	blood
40	chr11:74690000-74699400	Weak transcription	NHDF-Ad	bronchial
41	chr11:74690200-74699200	Weak transcription	H1 Cell Line	embryonic stem cell
42	chr11:74690200-74699200	Weak transcription	HUES48 Cell Line	embryonic stem cell
43	chr11:74690200-74699200	Weak transcription	Primary T helper 17 cells PMA-I stimulated	--
44	chr11:74690200-74699200	Weak transcription	Primary T cells effector/memory enriched fromperipheralblood	blood
45	chr11:74690200-74699600	Weak transcription	Small Intestine	intestine
46	chr11:74690400-74699200	Weak transcription	Brain Angular Gyrus	brain
47	chr11:74690600-74699400	Weak transcription	Ovary	ovary
48	chr11:74691000-74699200	Weak transcription	HUES64 Cell Line	embryonic stem cell
49	chr11:74691000-74699200	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
50	chr11:74691200-74699200	Weak transcription	iPS-18 Cell Line	embryonic stem cell

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links