Variant report

Variant	rs740363
Chromosome Location	chr10:118575606-118575607
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr10:118567627..118571222-chr10:118574932..118576886,3	MCF-7	breast:

Extended variants
information (count: 18 )
Associated
traits (count: 5 )

rSNPs within LD-proxies of this variant (count:18)

rs_ID	r²[population]
rs10787730	1.00[CHB][hapmap];0.85[JPT][hapmap];0.92[YRI][hapmap];0.87[AFR][1000 genomes];0.88[AMR][1000 genomes];0.92[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs10886014	0.81[CEU][hapmap];0.86[CHB][hapmap];1.00[JPT][hapmap];0.85[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs11197835	0.85[JPT][hapmap]
rs11591751	0.89[ASN][1000 genomes]
rs11596173	0.89[AFR][1000 genomes];0.88[AMR][1000 genomes];0.92[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs1614092	0.88[AMR][1000 genomes];0.90[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs1626678	0.89[AFR][1000 genomes];0.95[AMR][1000 genomes];0.96[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs1637556	0.83[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs1637558	0.89[AFR][1000 genomes];0.83[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs1681721	0.90[AMR][1000 genomes];0.93[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs1681723	0.83[AMR][1000 genomes];0.91[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs1681725	0.93[AMR][1000 genomes];0.94[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs1681748	0.91[AFR][1000 genomes];0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs2291316	0.85[AMR][1000 genomes];0.93[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs4752013	0.83[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs726525	0.81[CEU][hapmap];0.86[CHB][hapmap];1.00[JPT][hapmap];0.86[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs9420210	0.82[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs9421242	0.81[EUR][1000 genomes];0.89[ASN][1000 genomes]

Variant related diseases (count:1)

Disease	PMID	Source
Heart failure	17903304	GWAS catalog

mRNA abundance (count:4)

SNP	Gene	Cis/trans	Tissue	Source
rs740363	MAEL	trans	cerebellum	SCAN
rs740363	KIAA1598	cis	multi-tissue	Pritchard
rs740363	FAM160B1	cis	parietal	SCAN
rs740363	DKFZp781N1041	cis	multi-tissue	Pritchard

Chromatin state (count:25 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:118560600-118586200	Weak transcription	H9 Cell Line	embryonic stem cell
2	chr10:118569600-118586200	Weak transcription	ES-I3 Cell Line	embryonic stem cell
3	chr10:118569600-118592600	Weak transcription	Pancreas	Pancrea
4	chr10:118575000-118576000	Enhancers	Fetal Brain Male	brain
5	chr10:118575200-118575800	Enhancers	Foreskin Melanocyte Primary Cells skin03	Skin
6	chr10:118575200-118575800	Enhancers	Brain Cingulate Gyrus	brain
7	chr10:118575200-118576000	Bivalent Enhancer	Brain Hippocampus Middle	brain
8	chr10:118575200-118576200	Enhancers	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
9	chr10:118575200-118576600	Enhancers	NH-A	brain
10	chr10:118575400-118575800	Enhancers	H1 Derived Mesenchymal Stem Cells	ES cell derived
11	chr10:118575400-118575800	Bivalent Enhancer	Foreskin Melanocyte Primary Cells skin01	Skin
12	chr10:118575400-118575800	Flanking Active TSS	Brain Anterior Caudate	brain
13	chr10:118575400-118575800	Enhancers	Osteobl	bone
14	chr10:118575400-118576000	Enhancers	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
15	chr10:118575400-118576000	Bivalent Enhancer	IMR90 fetal lung fibroblasts Cell Line	lung
16	chr10:118575400-118576000	Bivalent Enhancer	Muscle Satellite Cultured Cells	--
17	chr10:118575400-118576000	Bivalent Enhancer	Brain Substantia Nigra	brain
18	chr10:118575400-118576000	Enhancers	HSMMtube	muscle
19	chr10:118575400-118576200	Enhancers	Brain Germinal Matrix	brain
20	chr10:118575400-118576200	Bivalent Enhancer	Fetal Adrenal Gland	Adrenal Gland
21	chr10:118575400-118576400	Enhancers	iPS DF 19.11 Cell Line	embryonic stem cell
22	chr10:118575600-118575800	Bivalent Enhancer	Breast Myoepithelial Primary Cells	Breast
23	chr10:118575600-118576000	Bivalent Enhancer	Brain Inferior Temporal Lobe	brain
24	chr10:118575600-118576200	Enhancers	ES-UCSF4 Cell Line	embryonic stem cell
25	chr10:118575600-118576400	Enhancers	HSMM	muscle

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links