Variant report

Variant	rs45570334
Chromosome Location	chr11:73693801-73693802
allele	C/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:310)
CpG islands
(count:61)
Chromatin interactive
region (count:32)
LncRNA
region (count:0)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:310 , 50 per page) page: 1 2 3 4 5 6 7

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	EP300	chr11:73693683-73694770	GM12878	blood:	n/a	chr11:73694280-73694289 chr11:73694276-73694290 chr11:73694618-73694627
2	TAF1	chr11:73693512-73695148	MCF-7	breast:	n/a	n/a
3	TBP	chr11:73693710-73694541	GM12878	blood:	n/a	n/a
4	POLR2A	chr11:73693424-73694898	MCF-7	breast:	n/a	n/a
5	RCOR1	chr11:73693684-73695036	Hela-S3	cervix:	n/a	n/a
6	MAFK	chr11:73693673-73693862	Hela-S3	cervix:	n/a	n/a
7	IRF1	chr11:73693669-73694925	K562	blood:	n/a	n/a
8	POLR2A	chr11:73693599-73694987	K562	blood:	n/a	n/a
9	TBP	chr11:73693635-73695009	K562	blood:	n/a	n/a
10	MYC	chr11:73693716-73695126	K562	blood:	n/a	chr11:73694793-73694800
11	CBX3	chr11:73693585-73695066	K562	blood:	n/a	n/a
12	MAX	chr11:73693500-73695415	K562	blood:	n/a	chr11:73694793-73694800
13	RELA	chr11:73693670-73694706	GM18951	blood:	n/a	n/a
14	POLR2A	chr11:73693632-73694762	A549	lung:	n/a	n/a
15	POLR2A	chr11:73693446-73694886	Hela-S3	cervix:	n/a	n/a
16	MYC	chr11:73693692-73695073	K562	blood:	n/a	chr11:73694793-73694800
17	ETS1	chr11:73693628-73694614	A549	lung:	n/a	chr11:73694276-73694291 chr11:73693900-73693911 chr11:73694280-73694287 chr11:73694277-73694288
18	POLR2A	chr11:73692165-73694830	GM12892	blood:	n/a	n/a
19	MAX	chr11:73693571-73695186	HepG2	liver:	n/a	chr11:73694793-73694800
20	SIN3A	chr11:73693417-73694808	H1-hESC	embryonic stem cell:	n/a	chr11:73694649-73694662 chr11:73694357-73694368
21	POLR2A	chr11:73693576-73694911	U87	brain:	n/a	n/a
22	MAX	chr11:73692870-73695207	A549	lung:	n/a	chr11:73694793-73694800
23	ELK1	chr11:73693727-73693848	Hela-S3	cervix:	n/a	n/a
24	POLR2A	chr11:73693665-73693920	A549	lung:	n/a	n/a
25	SRF	chr11:73693741-73695017	MCF-7	breast:	n/a	chr11:73694643-73694653 chr11:73694915-73694929
26	POLR2A	chr11:73693595-73694956	GM18505	blood:	n/a	n/a
27	MYC	chr11:73693661-73695348	K562	blood:	n/a	chr11:73694793-73694800
28	CREB1	chr11:73693636-73694849	A549	lung:	n/a	n/a
29	MYC	chr11:73693652-73693941	HUVEC	blood vessel:	n/a	n/a
30	ELF1	chr11:73693475-73695065	GM12878	blood:	n/a	chr11:73694615-73694627 chr11:73694638-73694650 chr11:73694280-73694291 chr11:73693902-73693911
31	MXI1	chr11:73693655-73694969	K562	blood:	n/a	n/a
32	FOXM1	chr11:73693617-73694711	GM12878	blood:	n/a	n/a
33	YY1	chr11:73693178-73693903	GM12892	blood:	n/a	n/a
34	BHLHE40	chr11:73693605-73694976	GM12878	blood:	n/a	chr11:73693897-73693913 chr11:73694626-73694635 chr11:73694623-73694636 chr11:73694625-73694634 chr11:73693896-73693912 chr11:73694625-73694634
35	E2F6	chr11:73693612-73695266	K562	blood:	n/a	chr11:73693859-73693873 chr11:73694561-73694573 chr11:73693905-73693914
36	POLR2A	chr11:73693606-73694843	HCT-116	colon:	n/a	n/a
37	POLR2A	chr11:73693530-73694973	HUVEC	blood vessel:	n/a	n/a
38	BACH1	chr11:73693707-73693861	H1-hESC	embryonic stem cell:	n/a	n/a
39	MAX	chr11:73693679-73694969	HepG2	liver:	n/a	chr11:73694793-73694800
40	POLR2A	chr11:73693610-73694805	GM12878	blood:	n/a	n/a
41	POLR2A	chr11:73693647-73694875	K562	blood:	n/a	n/a
42	GATA3	chr11:73693685-73693966	T-47D	breast:	n/a	n/a
43	POLR2A	chr11:73693523-73694913	ECC-1	luminal epithelium:	n/a	n/a
44	NRF1	chr11:73693665-73694558	GM12878	blood:	n/a	chr11:73693893-73693907 chr11:73693896-73693905
45	HA-E2F1	chr11:73693670-73694708	Hela-S3	cervix:	n/a	chr11:73693859-73693873 chr11:73694561-73694573 chr11:73693905-73693914
46	POLR2A	chr11:73692325-73694919	SK-N-MC	brain:	n/a	n/a
47	POLR2A	chr11:73690723-73695117	GM12878	blood:	n/a	n/a
48	POLR2A	chr11:73693505-73694583	ProgFib	skin:	n/a	n/a
49	RCOR1	chr11:73693690-73695489	K562	blood:	n/a	n/a
50	YY1	chr11:73693641-73694823	HepG2	liver:	n/a	chr11:73693905-73693914 chr11:73693899-73693913 chr11:73693902-73693911

(count:61 , 50 per page) page: 1 2

No.	Chromosome Location	Cell Line	Cell type	Cell Stage
1	chr11:73693792-73693842	GM12891	blood:	n/a
2	chr11:73693792-73693842	HRPEpiC	eye:	n/a
3	chr11:73693792-73693842	HAEpiC	amniotic membrane:	n/a
4	chr11:73693792-73693842	HNPCEpiC	eye:	n/a
5	chr11:73693792-73693842	ProgFib	skin:	n/a
6	chr11:73693792-73693842	GM12878	blood:	n/a
7	chr11:73693792-73693842	NB4	blood:	n/a
8	chr11:73693792-73693842	HEK293	kidney:	embryo
9	chr11:73693792-73693842	GM19239	blood:	n/a
10	chr11:73693792-73693842	K562	blood:	n/a
11	chr11:73693792-73693842	HMEC	breast:	n/a
12	chr11:73693792-73693842	HL-60	blood:	n/a
13	chr11:73693792-73693842	HUVEC	blood vessel:	n/a
14	chr11:73693792-73693842	AG04450	lung:	fetal
15	chr11:73693792-73693842	GM12892	blood:	n/a
16	chr11:73693792-73693842	GM06990	blood:	n/a
17	chr11:73693792-73693842	AoSMC	blood vessel:	n/a
18	chr11:73693792-73693842	AG09309	skin:	n/a
19	chr11:73693792-73693842	SKMC	muscle:	n/a
20	chr11:73693792-73693842	HRE	kidney:	n/a
21	chr11:73693792-73693842	NHDF-neo	bronchial:	n/a
22	chr11:73693792-73693842	HCT-116	colon:	n/a
23	chr11:73693792-73693842	CMK	blood:	n/a
24	chr11:73693792-73693842	RPTEC	kidney:	n/a
25	chr11:73693792-73693842	U87	brain:	n/a
26	chr11:73693792-73693842	PFSK-1	brain:	n/a
27	chr11:73693792-73693842	HCF	heart:	n/a
28	chr11:73693792-73693842	HCM	heart:	n/a
29	chr11:73693792-73693842	PrEC	prostate:	n/a
30	chr11:73693792-73693842	Hela-S3	cervix:	n/a
31	chr11:73693792-73693842	Jurkat	blood:	n/a
32	chr11:73693792-73693842	HRCEpiC	kidney:	n/a
33	chr11:73693792-73693842	HIPEpiC	eye:	n/a
34	chr11:73693792-73693842	NH-A	brain:	n/a
35	chr11:73693792-73693842	A549	lung:	n/a
36	chr11:73693792-73693842	MCF10A-Er-Src	breast:	n/a
37	chr11:73693792-73693842	LNCaP	prostate:	n/a
38	chr11:73693792-73693842	MCF-7	breast:	n/a
39	chr11:73693792-73693842	BE2_C	brain:	n/a
40	chr11:73693792-73693842	Caco-2	colon:	n/a
41	chr11:73693792-73693842	PANC-1	pancreas:	n/a
42	chr11:73693792-73693842	IMR90	lung:	fetal
43	chr11:73693792-73693842	Hepatocyte	liver:	n/a
44	chr11:73693792-73693842	NT2-D1	testis:	n/a
45	chr11:73693792-73693842	SK-N-MC	brain:	n/a
46	chr11:73693792-73693842	NHBE	bronchial:	n/a
47	chr11:73693792-73693842	T-47D	breast:	n/a
48	chr11:73693792-73693842	HepG2	liver:	n/a
49	chr11:73693792-73693842	SK-N-SH_RA	brain:	n/a
50	chr11:73693792-73693842	AG10803	skin:	n/a

(count:32 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr11:73693232..73694230-chr20:47895223..47895801,2	NB4	blood:
2	chr11:73693729..73694295-chr9:124132178..124132678,2	Hela-S3	cervix:
3	chr11:73692980..73694641-chr11:73795807..73797869,2	K562	blood:
4	chr11:73692359..73693859-chr11:73914650..73916719,2	K562	blood:
5	chr11:73693398..73694504-chr15:89877365..89878370,3	Hela-S3	cervix:
6	chr11:73692800..73696318-chr11:73880815..73883748,5	MCF-7	breast:
7	chr11:73693535..73694204-chr12:57472203..57472855,2	NB4	blood:
8	chr11:73586614..73588298-chr11:73691679..73694031,2	MCF-7	breast:
9	chr11:73691904..73697409-chr11:73796369..73799985,7	K562	blood:
10	chr11:73693268..73694066-chr6:27100220..27100998,2	Hela-S3	cervix:
11	chr11:73693694..73694548-chr16:67204296..67205190,2	Hela-S3	cervix:
12	chr11:73691320..73695538-chr11:73704392..73710067,8	MCF-7	breast:
13	chr11:73693160..73695633-chr11:73711332..73713417,2	K562	blood:
14	chr11:73693503..73694446-chr2:88315632..88316521,2	NB4	blood:
15	chr11:73693159..73695424-chr11:73716966..73719233,2	MCF-7	breast:
16	chr11:73691455..73695821-chr11:73881160..73884452,10	K562	blood:
17	chr11:73693595..73694320-chr17:33914216..33914985,2	Hela-S3	cervix:
18	chr11:73693433..73693962-chr5:180670557..180671135,2	NB4	blood:
19	chr11:73661884..73663494-chr11:73691354..73693894,2	MCF-7	breast:
20	chr11:73693723..73696564-chr11:73880690..73883464,7	K562	blood:
21	chr11:73692520..73695585-chr11:73801085..73803833,3	MCF-7	breast:
22	chr11:73691101..73695528-chr11:73777647..73786599,14	MCF-7	breast:
23	chr11:73692887..73694821-chr11:73796088..73798230,2	MCF-7	breast:
24	chr11:73693782..73695320-chr11:73743526..73745604,2	MCF-7	breast:
25	chr11:73692678..73695547-chr11:74458881..74460384,2	K562	blood:
26	chr11:73584965..73587189-chr11:73691735..73694698,2	K562	blood:
27	chr11:73587462..73590069-chr11:73692817..73694652,2	K562	blood:
28	chr11:73690232..73696227-chr11:73800984..73805427,5	MCF-7	breast:
29	chr11:73691754..73696567-chr11:73778152..73784121,11	MCF-7	breast:
30	chr11:73693506..73694499-chr9:32573046..32573748,2	NB4	blood:
31	chr11:73690208..73697157-chr11:73720249..73724103,9	K562	blood:
32	chr1:147806342..147807199-chr11:73693656..73694217,2	Hela-S3	cervix:

No data

Variant related genes	Relation type
UCP2	TF binding region
UCP2	CpG island
ENSG00000209042	Chromatin interaction
ENSG00000166439	Chromatin interaction
ENSG00000256723	Chromatin interaction
ENSG00000140939	Chromatin interaction
ENSG00000175575	Chromatin interaction
ENSG00000214517	Chromatin interaction
ENSG00000168014	Chromatin interaction
ENSG00000124635	Chromatin interaction
ENSG00000181924	Chromatin interaction
ENSG00000222724	Chromatin interaction
ENSG00000140521	Chromatin interaction
ENSG00000175564	Chromatin interaction
ENSG00000166881	Chromatin interaction
ENSG00000187726	Chromatin interaction
ENSG00000204628	Chromatin interaction
ENSG00000196787	Chromatin interaction
ENSG00000165264	Chromatin interaction
ENSG00000261441	Chromatin interaction
ENSG00000006125	Chromatin interaction
ENSG00000148175	Chromatin interaction
ENSG00000202408	Chromatin interaction

Extended variants
information (count: 32 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:29)

rs_ID	r²[population]
rs11821823	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs11822794	1.00[EUR][1000 genomes]
rs11825819	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs17132408	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs17132421	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs17132422	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs17132438	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs17132488	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs17132555	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs45476292	1.00[EUR][1000 genomes]
rs55840703	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs55893487	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs55939206	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs56117405	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs56168571	0.86[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs56340309	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs56723437	0.81[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs56767203	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs57579114	1.00[EUR][1000 genomes]
rs58792356	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs59621450	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs60093210	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs60520592	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs61085412	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs61581672	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs61616797	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs61701946	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs7110607	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs73543094	1.00[EUR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:3 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv492091	chr11:73285970-73844424	Weak transcription Strong transcription Flanking Active TSS Genic enhancers Enhancers ZNF genes & repeats Active TSS Bivalent Enhancer Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	85 gene(s)	inside rSNPs	diseases
2	esv1827060	chr11:73670645-73694754	Weak transcription Flanking Active TSS Transcr. at gene 5' and 3' Genic enhancers Active TSS Enhancers Strong transcription Bivalent/Poised TSS Flanking Bivalent TSS/Enh Bivalent Enhancer ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	34 gene(s)	inside rSNPs	diseases
3	nsv520299	chr11:73684294-73694754	Enhancers Flanking Active TSS Strong transcription Active TSS Transcr. at gene 5' and 3' Weak transcription Genic enhancers Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region miRNA target site	33 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:126 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:73688400-73694400	Transcr. at gene 5' and 3'	Primary T helper naive cells fromperipheralblood	blood
2	chr11:73691800-73695000	Active TSS	Colon Smooth Muscle	Colon
3	chr11:73692000-73694600	Active TSS	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
4	chr11:73692000-73694600	Active TSS	Fetal Intestine Large	intestine
5	chr11:73692200-73694600	Active TSS	Primary T cells from cord blood	blood
6	chr11:73692200-73694600	Active TSS	Primary T killer naive cells fromperipheralblood	blood
7	chr11:73692200-73694800	Active TSS	Brain Hippocampus Middle	brain
8	chr11:73692200-73695000	Flanking Active TSS	Adipose Nuclei	Adipose
9	chr11:73692200-73695000	Active TSS	Fetal Kidney	kidney
10	chr11:73692400-73694400	Active TSS	Sigmoid Colon	Sigmoid Colon
11	chr11:73692400-73694600	Active TSS	Primary T helper naive cells from peripheral blood	blood
12	chr11:73692400-73694600	Active TSS	HSMM	muscle
13	chr11:73692400-73694800	Active TSS	iPS DF 6.9 Cell Line	embryonic stem cell
14	chr11:73692400-73694800	Active TSS	Small Intestine	intestine
15	chr11:73692400-73695200	Flanking Active TSS	Stomach Smooth Muscle	stomach
16	chr11:73692600-73694000	Active TSS	Liver	Liver
17	chr11:73692600-73694400	Active TSS	Fetal Lung	lung
18	chr11:73692600-73694400	Active TSS	GM12878-XiMat	blood
19	chr11:73692600-73694600	Active TSS	Primary T helper memory cells from peripheral blood 1	blood
20	chr11:73692600-73694600	Active TSS	Primary T cells effector/memory enriched fromperipheralblood	blood
21	chr11:73692600-73694800	Active TSS	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
22	chr11:73692600-73694800	Flanking Active TSS	H1 Derived Mesenchymal Stem Cells	ES cell derived
23	chr11:73692600-73694800	Active TSS	HUES64 Cell Line	embryonic stem cell
24	chr11:73692600-73694800	Active TSS	HSMMtube	muscle
25	chr11:73692600-73695000	Active TSS	Duodenum Smooth Muscle	Duodenum
26	chr11:73692600-73695000	Active TSS	Esophagus	oesophagus
27	chr11:73692800-73694400	Active TSS	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
28	chr11:73692800-73694400	Active TSS	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
29	chr11:73692800-73694400	Active TSS	Primary T cells fromperipheralblood	blood
30	chr11:73692800-73694400	Active TSS	Primary Natural Killer cells fromperipheralblood	blood
31	chr11:73692800-73694600	Active TSS	Primary T helper memory cells from peripheral blood 2	blood
32	chr11:73692800-73694600	Active TSS	Primary T helper cells PMA-I stimulated	--
33	chr11:73692800-73694600	Active TSS	Ganglion Eminence derived primary cultured neurospheres	brain
34	chr11:73692800-73694600	Active TSS	Fetal Intestine Small	intestine
35	chr11:73692800-73694600	Active TSS	A549	lung
36	chr11:73692800-73694800	Active TSS	ES-I3 Cell Line	embryonic stem cell
37	chr11:73692800-73694800	Active TSS	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
38	chr11:73692800-73694800	Active TSS	HUES48 Cell Line	embryonic stem cell
39	chr11:73692800-73694800	Active TSS	Primary T killer memory cells from peripheral blood	blood
40	chr11:73692800-73694800	Flanking Active TSS	Primary mononuclear cells fromperipheralblood	Blood
41	chr11:73692800-73695000	Active TSS	H9 Cell Line	embryonic stem cell
42	chr11:73693000-73694200	Active TSS	Muscle Satellite Cultured Cells	--
43	chr11:73693000-73694200	Active TSS	NHDF-Ad	bronchial
44	chr11:73693000-73694400	Active TSS	Primary B cells from cord blood	blood
45	chr11:73693000-73694400	Transcr. at gene 5' and 3'	Primary T helper 17 cells PMA-I stimulated	--
46	chr11:73693000-73694400	Active TSS	Foreskin Fibroblast Primary Cells skin02	Skin
47	chr11:73693000-73694400	Active TSS	Fetal Thymus	thymus
48	chr11:73693000-73694600	Active TSS	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
49	chr11:73693000-73694600	Active TSS	HUES6 Cell Line	embryonic stem cell
50	chr11:73693000-73694600	Active TSS	iPS DF 19.11 Cell Line	embryonic stem cell

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links