Variant report

Variant	rs6474525
Chromosome Location	chr8:38936987-38936988
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr8:38936688..38939079-chr8:38941163..38942951,2	K562	blood:

Extended variants
information (count: 51 )
Associated
traits (count: 5 )

rSNPs within LD-proxies of this variant (count:50)

rs_ID	r²[population]
rs10092021	0.99[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs10093975	0.83[CHB][hapmap];0.90[JPT][hapmap];0.91[YRI][hapmap]
rs10113077	0.84[CHB][hapmap]
rs10441608	1.00[CHB][hapmap];0.90[JPT][hapmap];1.00[YRI][hapmap];0.84[AFR][1000 genomes];0.81[AMR][1000 genomes];0.88[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs10809000	0.83[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.84[AFR][1000 genomes];0.88[AMR][1000 genomes];0.88[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs10809001	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs11784624	1.00[CEU][hapmap];1.00[CHB][hapmap];0.95[JPT][hapmap];1.00[YRI][hapmap];0.94[AFR][1000 genomes];0.96[AMR][1000 genomes];1.00[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs11985898	0.82[CEU][hapmap];0.81[JPT][hapmap];0.87[EUR][1000 genomes]
rs12156418	0.94[AFR][1000 genomes];0.96[AMR][1000 genomes];1.00[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs28434452	0.95[AFR][1000 genomes];0.93[AMR][1000 genomes];0.99[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs28563781	0.94[AFR][1000 genomes];0.98[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs28564878	0.95[AFR][1000 genomes];0.96[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs28579045	0.84[AFR][1000 genomes];0.84[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs28690874	0.82[AFR][1000 genomes];0.84[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs28868044	0.94[AFR][1000 genomes];0.96[AMR][1000 genomes];1.00[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs4075849	1.00[CEU][hapmap];1.00[CHB][hapmap];0.95[JPT][hapmap];0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs4269506	1.00[CEU][hapmap];0.86[JPT][hapmap];1.00[YRI][hapmap];0.95[AFR][1000 genomes];0.91[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs4495395	0.83[CHB][hapmap]
rs4517088	1.00[CEU][hapmap];0.90[JPT][hapmap];1.00[YRI][hapmap];0.96[AFR][1000 genomes];0.91[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs4615534	1.00[CEU][hapmap];0.91[JPT][hapmap];1.00[YRI][hapmap];0.95[AFR][1000 genomes];0.96[AMR][1000 genomes];1.00[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs4733904	0.95[AFR][1000 genomes];0.95[AMR][1000 genomes];0.99[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs4733971	0.97[AFR][1000 genomes];0.98[AMR][1000 genomes];0.98[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs55797573	0.92[AFR][1000 genomes];0.92[AMR][1000 genomes];0.93[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs59118660	0.89[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs59814883	0.93[AFR][1000 genomes];0.92[AMR][1000 genomes];0.99[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs6474517	0.82[AFR][1000 genomes];0.84[AMR][1000 genomes];0.85[EUR][1000 genomes]
rs67200247	0.94[AFR][1000 genomes];0.96[AMR][1000 genomes];1.00[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs6991383	0.82[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.84[AFR][1000 genomes];0.88[AMR][1000 genomes];0.88[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs6991968	0.83[CHB][hapmap];0.90[JPT][hapmap]
rs6997721	0.80[AFR][1000 genomes];0.86[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs7001985	0.86[JPT][hapmap];0.87[YRI][hapmap]
rs7006535	0.84[AFR][1000 genomes];0.88[AMR][1000 genomes];0.88[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs7013358	0.96[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs7015505	0.85[CEU][hapmap];1.00[CHB][hapmap];0.90[JPT][hapmap];1.00[YRI][hapmap];0.85[AFR][1000 genomes];0.89[AMR][1000 genomes];0.89[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs7464810	0.96[AFR][1000 genomes];0.96[AMR][1000 genomes];1.00[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs7818363	0.86[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.85[AFR][1000 genomes];0.89[AMR][1000 genomes];0.89[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs7821437	0.86[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.85[AMR][1000 genomes];0.89[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs7823125	0.90[JPT][hapmap]
rs7830975	0.81[AMR][1000 genomes];0.83[EUR][1000 genomes]
rs7831735	0.89[CHB][hapmap];0.90[JPT][hapmap]
rs7832284	1.00[CEU][hapmap];1.00[CHB][hapmap];0.95[JPT][hapmap];1.00[YRI][hapmap];0.95[AFR][1000 genomes];0.96[AMR][1000 genomes];1.00[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs7832578	0.83[CHB][hapmap]
rs7834967	0.83[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.82[AFR][1000 genomes];0.84[AMR][1000 genomes];0.85[EUR][1000 genomes]
rs7835604	0.84[AFR][1000 genomes];0.88[AMR][1000 genomes];0.87[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs7836422	0.89[CHB][hapmap];0.90[JPT][hapmap];0.86[YRI][hapmap]
rs7838874	0.82[CHB][hapmap]
rs7840044	0.82[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.95[YRI][hapmap];0.81[AFR][1000 genomes];0.86[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs7840270	0.90[JPT][hapmap]
rs7844927	0.84[AFR][1000 genomes];0.84[AMR][1000 genomes];0.83[EUR][1000 genomes]
rs9650347	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.94[AFR][1000 genomes];0.93[AMR][1000 genomes];0.98[EUR][1000 genomes];0.93[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:1 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1021581	chr8:38934014-39043954	Strong transcription Weak transcription Enhancers Genic enhancers Active TSS Flanking Bivalent TSS/Enh Flanking Active TSS ZNF genes & repeats Bivalent Enhancer Transcr. at gene 5' and 3' Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	3 gene(s)	inside rSNPs	diseases

mRNA abundance (count:5)

SNP	Gene	Cis/trans	Tissue	Source
rs6474525	ADAM32	cis	Artery Tibial	GTEx
rs6474525	ADAM32	cis	Artery Aorta	GTEx
rs6474525	ADAM32	cis	Thyroid	GTEx
rs6474525	ADAM32	cis	Adipose Subcutaneous	GTEx
rs6474525	ADAM32	cis	Nerve Tibial	GTEx

Chromatin state (count:101 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr8:38897400-38963400	Weak transcription	ES-WA7 Cell Line	embryonic stem cell
2	chr8:38902400-38947600	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
3	chr8:38905000-38960000	Weak transcription	HSMMtube	muscle
4	chr8:38911600-38947800	Weak transcription	Primary mononuclear cells fromperipheralblood	Blood
5	chr8:38911800-38949000	Weak transcription	Brain Substantia Nigra	brain
6	chr8:38911800-38964800	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
7	chr8:38912000-38949000	Weak transcription	Brain Angular Gyrus	brain
8	chr8:38914400-38964800	Weak transcription	Fetal Kidney	kidney
9	chr8:38914800-38964800	Weak transcription	Colonic Mucosa	Colon
10	chr8:38915200-38940000	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
11	chr8:38917600-38944400	Weak transcription	Esophagus	oesophagus
12	chr8:38917600-38949000	Weak transcription	Spleen	Spleen
13	chr8:38918000-38962600	Weak transcription	ES-I3 Cell Line	embryonic stem cell
14	chr8:38919000-38944400	Weak transcription	Lung	lung
15	chr8:38919000-38949000	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
16	chr8:38919000-38952600	Weak transcription	Rectal Smooth Muscle	rectum
17	chr8:38919000-38970400	Weak transcription	K562	blood
18	chr8:38919600-38964800	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
19	chr8:38920400-38940800	Weak transcription	Primary B cells from cord blood	blood
20	chr8:38920600-38938000	Weak transcription	Stomach Smooth Muscle	stomach
21	chr8:38920600-38963200	Weak transcription	iPS-18 Cell Line	embryonic stem cell
22	chr8:38920800-38940200	Weak transcription	HUES48 Cell Line	embryonic stem cell
23	chr8:38920800-38964800	Weak transcription	Fetal Brain Male	brain
24	chr8:38921000-38948000	Weak transcription	Aorta	Aorta
25	chr8:38921000-38948200	Weak transcription	Right Ventricle	heart
26	chr8:38921000-38949000	Weak transcription	Skeletal Muscle Male	skeletal muscle
27	chr8:38921000-38964800	Weak transcription	Brain Inferior Temporal Lobe	brain
28	chr8:38921000-38965000	Weak transcription	Gastric	stomach
29	chr8:38921600-38964800	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
30	chr8:38922000-38950400	Weak transcription	Fetal Brain Female	brain
31	chr8:38922600-38937800	Weak transcription	Fetal Muscle Trunk	muscle
32	chr8:38922600-38940200	Weak transcription	HUES6 Cell Line	embryonic stem cell
33	chr8:38922600-38940400	Weak transcription	GM12878-XiMat	blood
34	chr8:38923600-38945600	Weak transcription	Fetal Intestine Small	intestine
35	chr8:38923600-38949000	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
36	chr8:38926200-38963600	Strong transcription	Monocytes-CD14+_RO01746	blood
37	chr8:38927600-38940600	Weak transcription	iPS-20b Cell Line	embryonic stem cell
38	chr8:38927600-38945600	Strong transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
39	chr8:38928200-38943400	Strong transcription	HUVEC	blood vessel
40	chr8:38929200-38941600	Strong transcription	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
41	chr8:38929400-38938600	Strong transcription	Fetal Lung	lung
42	chr8:38929800-38950600	Strong transcription	Muscle Satellite Cultured Cells	--
43	chr8:38930200-38940400	Weak transcription	Psoas Muscle	Psoas
44	chr8:38930200-38940600	Weak transcription	Liver	Liver
45	chr8:38930200-38944400	Weak transcription	Pancreas	Pancrea
46	chr8:38930400-38940400	Weak transcription	Sigmoid Colon	Sigmoid Colon
47	chr8:38930600-38938000	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
48	chr8:38930600-38939800	Weak transcription	HUES64 Cell Line	embryonic stem cell
49	chr8:38930800-38944200	Weak transcription	Hela-S3	cervix
50	chr8:38931200-38948400	Weak transcription	Brain Hippocampus Middle	brain

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links