Variant report

Variant	rs11227742
Chromosome Location	chr11:66988742-66988743
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

Extended variants
information (count: 43 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:41)

rs_ID	r²[population]
rs10896161	1.00[EUR][1000 genomes]
rs10896165	0.84[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs11227689	1.00[ASW][hapmap];1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];1.00[JPT][hapmap];1.00[LWK][hapmap];1.00[MKK][hapmap];1.00[TSI][hapmap];1.00[YRI][hapmap]
rs11227690	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap]
rs11227696	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];1.00[JPT][hapmap];1.00[TSI][hapmap]
rs11227703	0.82[AFR][1000 genomes]
rs11227713	1.00[ASW][hapmap];1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];1.00[JPT][hapmap];1.00[TSI][hapmap];0.85[YRI][hapmap]
rs11227723	1.00[ASW][hapmap];1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];0.94[LWK][hapmap];1.00[MKK][hapmap];1.00[TSI][hapmap];1.00[YRI][hapmap];0.82[AFR][1000 genomes]
rs11227732	0.85[AFR][1000 genomes];1.00[EUR][1000 genomes]
rs11227740	1.00[ASW][hapmap];1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];1.00[JPT][hapmap];1.00[LWK][hapmap];1.00[MKK][hapmap];1.00[TSI][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11227744	1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11227745	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.85[YRI][hapmap];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11227746	1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11227750	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.94[AFR][1000 genomes];1.00[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11227751	0.94[AFR][1000 genomes];1.00[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs11227752	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.85[YRI][hapmap];1.00[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11227755	1.00[JPT][hapmap]
rs11227761	0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11227765	0.94[ASN][1000 genomes]
rs11227768	0.94[ASN][1000 genomes]
rs11227770	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.94[ASN][1000 genomes]
rs12223898	0.94[ASN][1000 genomes]
rs12274774	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];1.00[JPT][hapmap];1.00[TSI][hapmap];0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs12282264	1.00[EUR][1000 genomes]
rs17145414	1.00[ASW][hapmap];1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];1.00[JPT][hapmap];0.94[LWK][hapmap];1.00[MKK][hapmap];1.00[TSI][hapmap];1.00[YRI][hapmap];0.82[AFR][1000 genomes]
rs3730145	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];1.00[JPT][hapmap];1.00[TSI][hapmap];0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs56132056	0.91[ASN][1000 genomes]
rs58100805	0.97[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs61758508	0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs61889551	0.88[AFR][1000 genomes];0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs61889552	0.83[AFR][1000 genomes];0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs61891317	0.82[AFR][1000 genomes]
rs61891346	0.88[AFR][1000 genomes]
rs61891586	0.83[ASN][1000 genomes]
rs61891588	0.83[ASN][1000 genomes]
rs61891589	0.81[ASN][1000 genomes]
rs61891590	0.81[ASN][1000 genomes]
rs6591234	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];1.00[JPT][hapmap];1.00[TSI][hapmap]
rs6591235	0.85[EUR][1000 genomes]
rs7127431	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];1.00[JPT][hapmap];1.00[TSI][hapmap];0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs9630209	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];1.00[JPT][hapmap];1.00[TSI][hapmap];0.94[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv531397	chr11:66653381-67465721	Active TSS Enhancers Strong transcription Flanking Active TSS Weak transcription Transcr. at gene 5' and 3' Genic enhancers Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	271 gene(s)	inside rSNPs	diseases
2	nsv532287	chr11:66784014-67023899	Weak transcription Strong transcription Bivalent Enhancer Enhancers Flanking Active TSS Active TSS Transcr. at gene 5' and 3' Genic enhancers Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	48 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs11227742	RPS6KB2	cis	lymphoblastoid	seeQTL

Chromatin state (count:126 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:66936400-67006200	Weak transcription	Stomach Mucosa	stomach
2	chr11:66954600-66993000	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
3	chr11:66956400-67005000	Weak transcription	Fetal Heart	heart
4	chr11:66962200-66999000	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
5	chr11:66962600-66995000	Weak transcription	Psoas Muscle	Psoas
6	chr11:66964400-66989400	Strong transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
7	chr11:66964600-67002400	Strong transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
8	chr11:66965200-67006400	Weak transcription	ES-WA7 Cell Line	embryonic stem cell
9	chr11:66966400-66989400	Strong transcription	H9 Derived Neuron Cultured Cells	ES cell derived
10	chr11:66970400-66988800	Strong transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
11	chr11:66971400-66989200	Strong transcription	Placenta	Placenta
12	chr11:66972400-66989600	Strong transcription	Primary T cells fromperipheralblood	blood
13	chr11:66972600-66989000	Strong transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
14	chr11:66972800-67002600	Strong transcription	Fetal Muscle Trunk	muscle
15	chr11:66973000-66989200	Strong transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
16	chr11:66973000-67005400	Strong transcription	IMR90 fetal lung fibroblasts Cell Line	lung
17	chr11:66974400-66989000	Strong transcription	Primary T helper cells fromperipheralblood	blood
18	chr11:66974600-66989400	Strong transcription	Fetal Adrenal Gland	Adrenal Gland
19	chr11:66974600-66993000	Strong transcription	Dnd41	blood
20	chr11:66974600-66993200	Strong transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
21	chr11:66974600-66993400	Strong transcription	HUES48 Cell Line	embryonic stem cell
22	chr11:66974800-66997600	Strong transcription	Fetal Thymus	thymus
23	chr11:66975000-66989400	Strong transcription	Fetal Muscle Leg	muscle
24	chr11:66975000-66993200	Strong transcription	Primary T regulatory cells fromperipheralblood	blood
25	chr11:66976400-66993000	Strong transcription	Osteobl	bone
26	chr11:66977400-66989200	Strong transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
27	chr11:66980400-67002200	Strong transcription	ES-UCSF4 Cell Line	embryonic stem cell
28	chr11:66980800-67005600	Weak transcription	Pancreatic Islets	Pancreatic Islet
29	chr11:66981000-67003800	Strong transcription	Primary mononuclear cells fromperipheralblood	Blood
30	chr11:66981600-67005200	Strong transcription	Primary monocytes fromperipheralblood	blood
31	chr11:66981800-67006400	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
32	chr11:66982000-66991800	Strong transcription	iPS-20b Cell Line	embryonic stem cell
33	chr11:66982000-66993200	Strong transcription	GM12878-XiMat	blood
34	chr11:66982000-66997800	Strong transcription	Primary Natural Killer cells fromperipheralblood	blood
35	chr11:66982000-67005800	Strong transcription	Monocytes-CD14+_RO01746	blood
36	chr11:66982200-66988800	Strong transcription	Primary T cells from cord blood	blood
37	chr11:66982200-66988800	Strong transcription	Primary T killer memory cells from peripheral blood	blood
38	chr11:66982200-66989400	Strong transcription	iPS-18 Cell Line	embryonic stem cell
39	chr11:66982200-66989400	Strong transcription	Primary hematopoietic stem cells	blood
40	chr11:66982200-66989400	Strong transcription	Rectal Mucosa Donor 29	rectum
41	chr11:66982200-66989400	Strong transcription	Sigmoid Colon	Sigmoid Colon
42	chr11:66982200-66989400	Strong transcription	Skeletal Muscle Female	skeletal muscle
43	chr11:66982200-66992000	Strong transcription	Primary B cells from peripheral blood	blood
44	chr11:66982200-66993200	Strong transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
45	chr11:66982400-66989200	Strong transcription	Ganglion Eminence derived primary cultured neurospheres	brain
46	chr11:66982400-66989400	Strong transcription	Liver	Liver
47	chr11:66982400-66991800	Strong transcription	Cortex derived primary cultured neurospheres	brain
48	chr11:66982400-67003800	Strong transcription	Primary neutrophils fromperipheralblood	blood
49	chr11:66982600-66989400	Strong transcription	Foreskin Keratinocyte Primary Cells skin03	Skin
50	chr11:66982600-66992400	Strong transcription	Primary B cells from cord blood	blood

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links