Variant report

Variant	rs10953537
Chromosome Location	chr7:107027905-107027906
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr7:107027220..107028831-chr7:107032404..107035234,2	MCF-7	breast:
2	chr7:107026679..107030350-chr7:107031871..107033708,4	K562	blood:

Extended variants
information (count: 152 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:145)

rs_ID	r²[population]
rs1002935	0.93[ASN][1000 genomes]
rs1018946	0.91[AFR][1000 genomes];0.96[ASN][1000 genomes]
rs1018947	0.96[ASN][1000 genomes]
rs10487271	0.96[ASN][1000 genomes]
rs10953529	0.91[ASN][1000 genomes]
rs10953530	0.93[ASN][1000 genomes]
rs10953531	0.93[ASN][1000 genomes]
rs10953533	0.94[ASN][1000 genomes]
rs10953534	0.81[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs10953535	1.00[AFR][1000 genomes];0.98[AMR][1000 genomes];0.94[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs10953536	0.98[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs1121312	0.81[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11761181	0.81[AFR][1000 genomes];0.89[AMR][1000 genomes];0.91[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs11764448	0.81[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11766060	0.93[ASN][1000 genomes]
rs11766131	0.81[AFR][1000 genomes];0.91[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs11769527	0.81[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11769861	0.83[AFR][1000 genomes];0.98[AMR][1000 genomes];0.93[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11769901	0.87[AMR][1000 genomes];0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs11770061	0.81[AFR][1000 genomes];0.91[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs11773514	0.81[AFR][1000 genomes];0.89[AMR][1000 genomes];0.91[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12154285	0.98[AMR][1000 genomes];0.94[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs12155231	0.98[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs12531187	0.81[AFR][1000 genomes];0.89[AMR][1000 genomes];0.94[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs12532447	0.93[AMR][1000 genomes];0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12532514	0.98[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs12532849	0.89[AMR][1000 genomes];0.91[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs12532953	0.83[AFR][1000 genomes];0.93[ASN][1000 genomes]
rs12532967	0.93[AMR][1000 genomes];0.88[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12533516	0.93[AMR][1000 genomes];0.88[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12533767	0.83[AFR][1000 genomes];0.96[ASN][1000 genomes]
rs12534000	0.84[AMR][1000 genomes];0.91[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs12534676	0.81[AFR][1000 genomes];0.93[AMR][1000 genomes];0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12535081	0.98[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs12535093	0.92[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs12535258	0.87[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs12535814	0.89[AMR][1000 genomes];1.00[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs12536485	0.98[AMR][1000 genomes];0.93[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12536491	0.98[AMR][1000 genomes];0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12536603	0.98[AMR][1000 genomes];0.98[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12537011	1.00[AFR][1000 genomes];0.98[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12537374	0.96[ASN][1000 genomes]
rs12537730	0.91[AFR][1000 genomes];0.92[ASN][1000 genomes]
rs12537733	0.87[AMR][1000 genomes];0.91[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs12537785	0.89[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs12538090	0.84[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs12538769	0.94[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs12538848	0.94[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs12539895	0.84[EUR][1000 genomes]
rs12540475	0.93[ASN][1000 genomes]
rs1548523	0.81[AFR][1000 genomes];0.93[AMR][1000 genomes];0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs1548524	0.93[AMR][1000 genomes];0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs17349904	0.81[AFR][1000 genomes];0.93[ASN][1000 genomes]
rs17350182	0.94[ASN][1000 genomes]
rs17427123	0.93[ASN][1000 genomes]
rs17427158	0.81[AFR][1000 genomes];0.93[ASN][1000 genomes]
rs17427849	0.95[ASN][1000 genomes]
rs17428071	0.95[ASN][1000 genomes]
rs17428126	0.94[ASN][1000 genomes]
rs17428504	0.94[ASN][1000 genomes]
rs17429118	0.81[AFR][1000 genomes];0.89[AMR][1000 genomes];0.91[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs17429146	0.84[AMR][1000 genomes];0.91[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs17429825	0.96[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs1978085	0.83[EUR][1000 genomes]
rs1989814	1.00[AFR][1000 genomes];0.96[AMR][1000 genomes];0.98[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs2023892	0.93[ASN][1000 genomes]
rs2107318	0.91[AFR][1000 genomes];0.93[ASN][1000 genomes]
rs2107319	0.95[ASN][1000 genomes]
rs2189501	0.93[AMR][1000 genomes];0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs2249043	0.89[AMR][1000 genomes];0.91[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs2299422	0.89[AMR][1000 genomes];0.91[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs2395859	0.98[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2395880	0.91[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs2395881	0.81[AFR][1000 genomes];0.91[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs2894459	0.89[AMR][1000 genomes];0.91[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs34084719	0.83[EUR][1000 genomes]
rs3757713	0.83[AFR][1000 genomes];0.96[AMR][1000 genomes];1.00[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs3779498	0.81[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs3801958	0.89[AMR][1000 genomes];0.91[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs3801959	0.87[AMR][1000 genomes];0.91[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs3801963	0.94[ASN][1000 genomes]
rs3801965	0.81[AFR][1000 genomes];0.93[ASN][1000 genomes]
rs3815148	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs3823959	1.00[AFR][1000 genomes];0.98[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs3823960	1.00[AFR][1000 genomes];0.98[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4515482	0.90[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs4727670	0.91[ASN][1000 genomes]
rs4727671	0.95[ASN][1000 genomes]
rs4730224	0.88[ASN][1000 genomes]
rs4730226	0.81[AFR][1000 genomes];0.94[ASN][1000 genomes]
rs4730227	0.93[ASN][1000 genomes]
rs4730228	0.81[AFR][1000 genomes];0.80[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs4730229	0.81[AFR][1000 genomes];0.80[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs4730231	0.93[AMR][1000 genomes];0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs4730232	0.93[AMR][1000 genomes];0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs4730233	0.93[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs4730239	0.83[AMR][1000 genomes];0.95[EUR][1000 genomes]
rs4730241	0.83[AMR][1000 genomes];0.95[EUR][1000 genomes]
rs4730242	0.83[AMR][1000 genomes];0.95[EUR][1000 genomes]
rs5002976	0.96[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs57525841	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs58319984	0.87[AMR][1000 genomes];0.91[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs58663672	0.87[AMR][1000 genomes];0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs58689670	0.86[EUR][1000 genomes]
rs59782202	0.89[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs59900773	0.94[AMR][1000 genomes];0.94[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs60255281	0.87[AMR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs61406169	0.94[ASN][1000 genomes]
rs61511581	0.87[AMR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs61673847	0.94[ASN][1000 genomes]
rs6466162	0.94[ASN][1000 genomes]
rs6946036	1.00[AFR][1000 genomes];0.96[ASN][1000 genomes]
rs6947675	0.88[ASN][1000 genomes]
rs6949961	0.94[ASN][1000 genomes]
rs6951639	0.81[AFR][1000 genomes];0.85[ASN][1000 genomes]
rs6960813	0.81[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs6963917	0.93[AMR][1000 genomes];0.91[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs6964798	0.81[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs6964966	0.81[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs6965001	0.81[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs6967639	0.82[ASN][1000 genomes]
rs6967745	0.83[AFR][1000 genomes];0.93[ASN][1000 genomes]
rs6971675	1.00[AFR][1000 genomes];0.93[ASN][1000 genomes]
rs6971774	1.00[AFR][1000 genomes];0.93[ASN][1000 genomes]
rs6979368	0.84[EUR][1000 genomes]
rs7777976	0.96[ASN][1000 genomes]
rs7779062	0.96[ASN][1000 genomes]
rs7781947	0.81[AFR][1000 genomes];0.94[ASN][1000 genomes]
rs7783181	0.88[AMR][1000 genomes];0.93[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs7783562	0.96[ASN][1000 genomes]
rs7789500	0.91[ASN][1000 genomes]
rs7789678	0.89[ASN][1000 genomes]
rs7793594	0.96[ASN][1000 genomes]
rs7794915	0.90[ASN][1000 genomes]
rs7794965	0.93[ASN][1000 genomes]
rs7798223	1.00[AFR][1000 genomes];0.93[ASN][1000 genomes]
rs7800443	0.81[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs7803290	0.81[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs7804979	0.92[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs7807648	0.93[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs7809508	0.88[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs7810216	0.98[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs7981	0.91[AFR][1000 genomes];0.93[ASN][1000 genomes]
rs9641378	0.95[ASN][1000 genomes]
rs997311	0.81[AFR][1000 genomes];0.93[AMR][1000 genomes];0.91[EUR][1000 genomes];0.96[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:7 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	esv3383027	chr7:106802625-107096474	Enhancers Weak transcription Strong transcription Genic enhancers Flanking Active TSS Active TSS ZNF genes & repeats Transcr. at gene 5' and 3' Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	31 gene(s)	inside rSNPs	diseases
2	nsv888939	chr7:106849393-107045700	ZNF genes & repeats Strong transcription Weak transcription Enhancers Active TSS Flanking Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region miRNA target site	8 gene(s)	inside rSNPs	diseases
3	esv1825788	chr7:106897237-107136320	Weak transcription Enhancers ZNF genes & repeats Flanking Active TSS Strong transcription Genic enhancers Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	10 gene(s)	inside rSNPs	diseases
4	nsv1024793	chr7:106900877-107170312	Strong transcription Weak transcription Enhancers Active TSS ZNF genes & repeats Flanking Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	10 gene(s)	inside rSNPs	diseases
5	nsv608073	chr7:106960515-107063686	Strong transcription ZNF genes & repeats Enhancers Weak transcription Active TSS Genic enhancers Flanking Active TSS	Chromatin interactive region	4 gene(s)	inside rSNPs	diseases
6	esv1832266	chr7:106961882-107136320	Weak transcription Strong transcription Enhancers ZNF genes & repeats Active TSS Flanking Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	9 gene(s)	inside rSNPs	diseases
7	nsv1033979	chr7:107003734-107877761	Strong transcription Enhancers Weak transcription Active TSS Flanking Bivalent TSS/Enh ZNF genes & repeats Genic enhancers Bivalent/Poised TSS Flanking Active TSS Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	62 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs10953537	GPR22	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:73 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr7:107001400-107031200	Weak transcription	H9 Cell Line	embryonic stem cell
2	chr7:107001400-107037600	Weak transcription	Spleen	Spleen
3	chr7:107001400-107053600	Weak transcription	Sigmoid Colon	Sigmoid Colon
4	chr7:107003200-107031400	Weak transcription	Fetal Intestine Large	intestine
5	chr7:107003600-107045000	Weak transcription	Breast Myoepithelial Primary Cells	Breast
6	chr7:107003800-107038800	Weak transcription	Primary T regulatory cells fromperipheralblood	blood
7	chr7:107003800-107048400	Weak transcription	Dnd41	blood
8	chr7:107003800-107050200	Weak transcription	Primary T cells fromperipheralblood	blood
9	chr7:107008400-107048200	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
10	chr7:107013200-107038600	Weak transcription	Foreskin Melanocyte Primary Cells skin03	Skin
11	chr7:107022200-107053000	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
12	chr7:107023000-107028000	Weak transcription	Brain Hippocampus Middle	brain
13	chr7:107023800-107030800	Weak transcription	Fetal Kidney	kidney
14	chr7:107024600-107038200	Weak transcription	Primary T helper cells PMA-I stimulated	--
15	chr7:107024600-107045000	Weak transcription	Pancreatic Islets	Pancreatic Islet
16	chr7:107025000-107038800	Weak transcription	Lung	lung
17	chr7:107025000-107039800	Weak transcription	Fetal Intestine Small	intestine
18	chr7:107025800-107039600	Weak transcription	Primary T cells from cord blood	blood
19	chr7:107026200-107028200	Enhancers	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
20	chr7:107026200-107029000	Enhancers	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
21	chr7:107026200-107029400	Enhancers	HUES64 Cell Line	embryonic stem cell
22	chr7:107026400-107028800	Enhancers	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
23	chr7:107026800-107028000	Enhancers	iPS DF 6.9 Cell Line	embryonic stem cell
24	chr7:107026800-107028000	Enhancers	Fetal Muscle Trunk	muscle
25	chr7:107026800-107028000	Enhancers	Fetal Muscle Leg	muscle
26	chr7:107026800-107028000	Enhancers	Left Ventricle	heart
27	chr7:107026800-107028000	Enhancers	Psoas Muscle	Psoas
28	chr7:107026800-107028000	Enhancers	K562	blood
29	chr7:107026800-107028200	Enhancers	IMR90 fetal lung fibroblasts Cell Line	lung
30	chr7:107026800-107028400	Enhancers	H1 Cell Line	embryonic stem cell
31	chr7:107026800-107028600	Enhancers	HUES6 Cell Line	embryonic stem cell
32	chr7:107027000-107028200	Enhancers	ES-I3 Cell Line	embryonic stem cell
33	chr7:107027000-107028200	Enhancers	ES-UCSF4 Cell Line	embryonic stem cell
34	chr7:107027000-107028400	Enhancers	HUES48 Cell Line	embryonic stem cell
35	chr7:107027000-107028600	Enhancers	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
36	chr7:107027000-107028800	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
37	chr7:107027000-107028800	Enhancers	Fetal Adrenal Gland	Adrenal Gland
38	chr7:107027000-107028800	Enhancers	NHDF-Ad	bronchial
39	chr7:107027200-107028000	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
40	chr7:107027200-107028000	Genic enhancers	Foreskin Fibroblast Primary Cells skin01	Skin
41	chr7:107027200-107028000	Enhancers	Brain Anterior Caudate	brain
42	chr7:107027200-107028000	Enhancers	Placenta	Placenta
43	chr7:107027200-107028200	Enhancers	Fetal Stomach	stomach
44	chr7:107027200-107028400	Enhancers	iPS-15b Cell Line	embryonic stem cell
45	chr7:107027200-107028400	Enhancers	NH-A	brain
46	chr7:107027200-107028600	Enhancers	Adipose Nuclei	Adipose
47	chr7:107027200-107028800	Enhancers	Fetal Heart	heart
48	chr7:107027200-107029000	Enhancers	NHLF	lung
49	chr7:107027400-107028200	Flanking Active TSS	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
50	chr7:107027400-107028200	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Female	--

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