Variant report

Variant	rs11015566
Chromosome Location	chr10:27430758-27430759
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr10:27411542..27413945-chr10:27429533..27432280,2	K562	blood:

Extended variants
information (count: 147 )
Associated
traits (count: 5 )

rSNPs within LD-proxies of this variant (count:147)

rs_ID	r²[population]
rs10458707	0.91[CHB][hapmap]
rs10764664	0.91[CHB][hapmap]
rs10764665	0.91[CHB][hapmap]
rs10764667	0.91[CHB][hapmap]
rs10764669	0.91[CHB][hapmap]
rs10764673	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs10764675	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs10764676	0.92[ASN][1000 genomes]
rs10764680	0.81[ASN][1000 genomes]
rs10764684	0.89[ASN][1000 genomes]
rs10764686	0.95[CHB][hapmap]
rs10829162	0.96[CHB][hapmap];0.95[JPT][hapmap]
rs10829163	0.82[CEU][hapmap];0.95[CHB][hapmap];0.95[JPT][hapmap]
rs10829164	0.83[CEU][hapmap]
rs10829167	0.82[CEU][hapmap];0.95[CHB][hapmap];0.95[JPT][hapmap]
rs10829172	0.86[CHB][hapmap]
rs10829173	0.91[CHB][hapmap]
rs10829174	0.91[CHB][hapmap]
rs10829180	0.81[ASN][1000 genomes]
rs10829181	0.81[ASN][1000 genomes]
rs10829183	0.80[AFR][1000 genomes];0.89[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs10829185	0.93[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs10829188	0.91[ASN][1000 genomes]
rs10829191	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs10829192	1.00[CEU][hapmap];0.81[CHB][hapmap];0.95[JPT][hapmap];0.96[YRI][hapmap];0.96[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs10829193	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs10829194	1.00[CEU][hapmap];1.00[YRI][hapmap];0.99[AFR][1000 genomes];0.93[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs10829197	0.80[ASN][1000 genomes]
rs10829200	0.89[ASN][1000 genomes]
rs10829201	0.95[CHB][hapmap]
rs11015507	0.81[YRI][hapmap]
rs11015511	0.91[YRI][hapmap]
rs11015522	0.91[CHB][hapmap];0.81[ASN][1000 genomes]
rs11015529	0.93[AMR][1000 genomes];0.96[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs11015530	0.93[AMR][1000 genomes];0.94[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs11015532	0.87[AFR][1000 genomes];0.96[AMR][1000 genomes];0.97[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11015536	0.97[AFR][1000 genomes];0.93[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs11015538	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11015542	0.94[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11015548	0.94[AFR][1000 genomes];0.98[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11015549	0.92[ASN][1000 genomes]
rs11015553	0.93[AFR][1000 genomes];0.93[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs11015554	0.91[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11015555	1.00[CEU][hapmap];1.00[YRI][hapmap];0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11015556	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11015558	1.00[CEU][hapmap];0.86[CHB][hapmap];0.81[JPT][hapmap];1.00[YRI][hapmap];0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11015559	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11015560	0.98[AFR][1000 genomes];0.98[AMR][1000 genomes];0.99[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11015563	0.92[ASN][1000 genomes]
rs11015564	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11015565	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11015570	0.91[CHB][hapmap];0.92[ASN][1000 genomes]
rs11015571	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs11015586	0.89[ASN][1000 genomes]
rs11015588	0.91[CHB][hapmap]
rs11015598	0.82[CEU][hapmap]
rs11015600	0.91[CHB][hapmap]
rs11813670	0.96[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12255977	1.00[CEU][hapmap];1.00[YRI][hapmap];0.97[AFR][1000 genomes];0.93[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs12259472	0.82[AFR][1000 genomes];0.93[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs12571792	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12572344	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.96[YRI][hapmap];0.96[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12766193	0.91[AMR][1000 genomes];0.91[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs12768114	0.93[AMR][1000 genomes];0.94[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs12769335	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12784464	0.95[AFR][1000 genomes];0.96[AMR][1000 genomes];1.00[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs1360007	0.92[ASN][1000 genomes]
rs1411283	0.91[CHB][hapmap]
rs1981296	0.95[CHB][hapmap];0.89[ASN][1000 genomes]
rs2183334	0.91[CHB][hapmap]
rs2185808	0.87[ASN][1000 genomes]
rs2274634	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.96[YRI][hapmap];0.96[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2274635	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.96[YRI][hapmap];0.96[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs2274741	0.83[CEU][hapmap];0.96[CHB][hapmap];0.95[JPT][hapmap]
rs2274743	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2275752	1.00[CEU][hapmap];1.00[YRI][hapmap];0.99[AFR][1000 genomes];0.93[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs2297143	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs2297145	0.88[CEU][hapmap];1.00[CHB][hapmap];0.95[JPT][hapmap];0.96[YRI][hapmap];0.93[AMR][1000 genomes];0.89[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs2297147	0.81[ASN][1000 genomes]
rs2297151	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2297152	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs2368217	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2887190	0.89[ASN][1000 genomes]
rs3737054	0.88[CEU][hapmap]
rs3737055	0.91[CHB][hapmap]
rs3758403	0.89[ASN][1000 genomes]
rs3780920	0.91[CHB][hapmap];0.80[JPT][hapmap];0.92[ASN][1000 genomes]
rs3780921	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs3780922	0.94[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs3780926	0.91[CHB][hapmap];0.92[ASN][1000 genomes]
rs3781100	0.91[AMR][1000 genomes];0.82[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs3824593	0.91[CHB][hapmap];0.83[JPT][hapmap];0.92[ASN][1000 genomes]
rs3904244	0.81[CEU][hapmap];0.96[CHB][hapmap];0.95[JPT][hapmap];0.86[ASN][1000 genomes]
rs3932559	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4018760	0.82[ASN][1000 genomes]
rs4142123	0.92[ASN][1000 genomes]
rs4747585	0.95[AFR][1000 genomes];0.98[AMR][1000 genomes];1.00[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs4749213	0.83[CEU][hapmap];0.96[CHB][hapmap];0.95[JPT][hapmap]
rs4749225	0.82[AFR][1000 genomes];0.84[AMR][1000 genomes];0.87[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs4749226	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs55741077	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs55955460	0.93[AFR][1000 genomes];0.93[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs6482596	0.91[CHB][hapmap];0.81[JPT][hapmap];0.92[ASN][1000 genomes]
rs6482600	0.91[CHB][hapmap];0.81[JPT][hapmap];0.89[ASN][1000 genomes]
rs6482601	0.91[CHB][hapmap];0.89[ASN][1000 genomes]
rs67177346	0.80[AFR][1000 genomes];0.91[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs67425403	0.91[AFR][1000 genomes];0.97[AMR][1000 genomes];0.92[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7067696	0.91[CHB][hapmap];0.81[JPT][hapmap];0.92[ASN][1000 genomes]
rs7068375	0.91[CHB][hapmap];0.90[ASN][1000 genomes]
rs7069942	0.90[ASN][1000 genomes]
rs7070117	0.90[ASN][1000 genomes]
rs7073381	0.82[AFR][1000 genomes];0.93[AMR][1000 genomes];0.94[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs7075448	1.00[CEU][hapmap];1.00[YRI][hapmap];0.84[AFR][1000 genomes];0.89[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs7079792	0.91[CHB][hapmap];0.89[ASN][1000 genomes]
rs7079885	0.89[ASN][1000 genomes]
rs7083768	0.83[CEU][hapmap];1.00[CHB][hapmap];0.95[JPT][hapmap];0.96[YRI][hapmap];0.93[AMR][1000 genomes];0.88[EUR][1000 genomes];0.87[ASN][1000 genomes]
rs7086311	0.88[CEU][hapmap];1.00[CHB][hapmap];0.95[JPT][hapmap];0.84[YRI][hapmap];0.93[AMR][1000 genomes];0.94[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs7086553	0.91[CHB][hapmap]
rs7086820	0.91[AMR][1000 genomes];0.84[EUR][1000 genomes];0.87[ASN][1000 genomes]
rs7087082	0.86[CHB][hapmap]
rs7088171	0.83[CEU][hapmap];0.96[CHB][hapmap]
rs7091128	0.91[CHB][hapmap];0.89[ASN][1000 genomes]
rs7091723	0.91[CHB][hapmap];0.89[ASN][1000 genomes]
rs7097009	0.91[CHB][hapmap]
rs7477806	0.89[ASN][1000 genomes]
rs7894187	0.85[ASN][1000 genomes]
rs7896012	0.91[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7900024	0.91[CHB][hapmap];0.92[ASN][1000 genomes]
rs7901653	0.91[CHB][hapmap];0.92[ASN][1000 genomes]
rs7901976	0.92[ASN][1000 genomes]
rs7902690	0.86[ASN][1000 genomes]
rs7907492	0.91[AFR][1000 genomes];0.91[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs7909444	1.00[CEU][hapmap];1.00[YRI][hapmap];0.97[AFR][1000 genomes];0.93[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs7910367	0.88[ASN][1000 genomes]
rs7910396	1.00[CEU][hapmap];1.00[YRI][hapmap];0.99[AFR][1000 genomes];0.93[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs7910430	0.91[CHB][hapmap];0.81[ASN][1000 genomes]
rs7910688	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.96[YRI][hapmap];0.93[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7914630	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7918395	0.87[ASN][1000 genomes]
rs7919621	0.91[CHB][hapmap]
rs7921222	1.00[CEU][hapmap];1.00[YRI][hapmap];0.95[AFR][1000 genomes];0.93[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs7921980	0.94[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs882474	0.91[CHB][hapmap];0.89[ASN][1000 genomes]
rs9299837	0.91[CHB][hapmap];0.89[ASN][1000 genomes]
rs9651378	0.88[CEU][hapmap];1.00[CHB][hapmap];0.95[JPT][hapmap];0.91[AMR][1000 genomes];0.82[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs9971193	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs9971335	0.84[AFR][1000 genomes];0.96[AMR][1000 genomes];0.97[EUR][1000 genomes];0.93[ASN][1000 genomes]

mRNA abundance (count:5)

SNP	Gene	Cis/trans	Tissue	Source
rs11015566	MASTL	cis	Skin Sun Exposed Lower leg	GTEx
rs11015566	MASTL	cis	lung	GTEx
rs11015566	MASTL	cis	Thyroid	GTEx
rs11015566	YME1L1	Cis_1M	lymphoblastoid	RTeQTL
rs11015566	MASTL	cis	Stomach	GTEx

Chromatin state (count:126 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:27389800-27441200	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
2	chr10:27390000-27442000	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
3	chr10:27390200-27435000	Weak transcription	Pancreatic Islets	Pancreatic Islet
4	chr10:27393800-27438600	Strong transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
5	chr10:27394200-27432600	Strong transcription	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
6	chr10:27394800-27432800	Strong transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
7	chr10:27395400-27437800	Strong transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
8	chr10:27396200-27440600	Strong transcription	Foreskin Keratinocyte Primary Cells skin03	Skin
9	chr10:27396800-27432000	Strong transcription	Foreskin Melanocyte Primary Cells skin03	Skin
10	chr10:27397600-27438600	Strong transcription	Fetal Thymus	thymus
11	chr10:27398200-27434200	Strong transcription	Ganglion Eminence derived primary cultured neurospheres	brain
12	chr10:27398400-27435200	Strong transcription	HUES64 Cell Line	embryonic stem cell
13	chr10:27398600-27431600	Strong transcription	HUES48 Cell Line	embryonic stem cell
14	chr10:27398600-27434800	Strong transcription	H9 Derived Neuron Cultured Cells	ES cell derived
15	chr10:27398600-27434800	Strong transcription	iPS-20b Cell Line	embryonic stem cell
16	chr10:27398600-27434800	Strong transcription	Primary T helper cells PMA-I stimulated	--
17	chr10:27398600-27436400	Strong transcription	Dnd41	blood
18	chr10:27398800-27438200	Strong transcription	Primary T helper cells fromperipheralblood	blood
19	chr10:27398800-27438200	Strong transcription	Primary Natural Killer cells fromperipheralblood	blood
20	chr10:27399000-27431400	Strong transcription	Placenta	Placenta
21	chr10:27399600-27435200	Strong transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
22	chr10:27399600-27438400	Strong transcription	Primary T regulatory cells fromperipheralblood	blood
23	chr10:27399800-27438600	Strong transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
24	chr10:27400400-27438400	Strong transcription	Liver	Liver
25	chr10:27401200-27435400	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
26	chr10:27403200-27431600	Strong transcription	NH-A	brain
27	chr10:27407800-27436400	Weak transcription	Right Ventricle	heart
28	chr10:27411200-27436000	Weak transcription	Esophagus	oesophagus
29	chr10:27412400-27440200	Weak transcription	Fetal Heart	heart
30	chr10:27413600-27430800	Strong transcription	Duodenum Smooth Muscle	Duodenum
31	chr10:27415400-27436200	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
32	chr10:27416800-27430800	Strong transcription	HUVEC	blood vessel
33	chr10:27418000-27436400	Weak transcription	Spleen	Spleen
34	chr10:27419200-27438600	Strong transcription	Monocytes-CD14+_RO01746	blood
35	chr10:27419200-27438800	Strong transcription	Primary monocytes fromperipheralblood	blood
36	chr10:27419400-27441400	Weak transcription	Stomach Mucosa	stomach
37	chr10:27419800-27436200	Weak transcription	Gastric	stomach
38	chr10:27421000-27430800	Weak transcription	Hela-S3	cervix
39	chr10:27421000-27436200	Weak transcription	Fetal Brain Male	brain
40	chr10:27421800-27431600	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
41	chr10:27423400-27436400	Weak transcription	Colonic Mucosa	Colon
42	chr10:27423600-27431400	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
43	chr10:27423600-27435000	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
44	chr10:27423800-27435600	Weak transcription	Placenta Amnion	Placenta Amnion
45	chr10:27424000-27432800	Weak transcription	ES-I3 Cell Line	embryonic stem cell
46	chr10:27424000-27432800	Weak transcription	Primary T helper memory cells from peripheral blood 2	blood
47	chr10:27424000-27436400	Weak transcription	Small Intestine	intestine
48	chr10:27424200-27432400	Weak transcription	Skeletal Muscle Male	skeletal muscle
49	chr10:27424600-27430800	Strong transcription	A549	lung
50	chr10:27424600-27431200	Weak transcription	ES-WA7 Cell Line	embryonic stem cell

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