Variant report

Variant	rs1966865
Chromosome Location	chr14:64975861-64975862
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:21)
CpG islands
(count:0)
Chromatin interactive
region (count:8)
LncRNA
region (count:0)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:21 , 50 per page) page: 1

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	POLR2A	chr14:64975476-64976162	GM12892	blood:	n/a	n/a
2	POLR2A	chr14:64975476-64976310	GM12878	blood:	n/a	n/a
3	MAX	chr14:64975823-64976085	K562	blood:	n/a	n/a
4	YY1	chr14:64975735-64976028	GM12892	blood:	n/a	n/a
5	POLR2A	chr14:64975487-64976290	GM12892	blood:	n/a	n/a
6	POLR2A	chr14:64975540-64976144	H1-hESC	embryonic stem cell:	n/a	n/a
7	POLR2A	chr14:64975800-64976092	H1-hESC	embryonic stem cell:	n/a	n/a
8	MAX	chr14:64975757-64976160	K562	blood:	n/a	n/a
9	E2F6	chr14:64975858-64976056	K562	blood:	n/a	n/a
10	HDAC2	chr14:64975812-64976074	HepG2	liver:	n/a	n/a
11	POLR2A	chr14:64975613-64976040	GM12878	blood:	n/a	n/a
12	POLR2A	chr14:64974968-64976293	GM12892	blood:	n/a	n/a
13	EP300	chr14:64975697-64976107	HepG2	liver:	n/a	n/a
14	POLR2A	chr14:64975800-64976130	Hela-S3	cervix:	n/a	n/a
15	POLR2A	chr14:64974140-64976033	A549	lung:	n/a	n/a
16	WRNIP1	chr14:64975546-64976013	GM12878	blood:	n/a	n/a
17	POLR2A	chr14:64975795-64976028	MCF-7	breast:	n/a	n/a
18	FOXA2	chr14:64975752-64976014	HepG2	liver:	n/a	n/a
19	MAX	chr14:64975765-64976190	H1-hESC	embryonic stem cell:	n/a	n/a
20	POLR2A	chr14:64975463-64976101	GM12878	blood:	n/a	n/a
21	UBTF	chr14:64975836-64976144	K562	blood:	n/a	n/a

No data

(count:8 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr14:64973370..64976227-chr20:52238868..52240910,2	MCF-7	breast:
2	chr14:64952330..64955037-chr14:64972049..64976293,4	K562	blood:
3	chr14:64973577..64975906-chr14:65136944..65139422,2	MCF-7	breast:
4	chr14:64974117..64976754-chr14:65005899..65008393,2	MCF-7	breast:
5	chr14:64959822..64962033-chr14:64973410..64976563,3	K562	blood:
6	chr14:64952581..64955037-chr14:64973773..64976293,2	K562	blood:
7	chr14:64967941..64976890-chr14:65001097..65012463,31	MCF-7	breast:
8	chr14:64812043..64814935-chr14:64975290..64978233,2	K562	blood:

No data

Variant related genes	Relation type
ZBTB25	TF binding region
ENSG00000126803	Chromatin interaction
ENSG00000259160	Chromatin interaction
ENSG00000259116	Chromatin interaction

Extended variants
information (count: 97 )
Associated
traits (count: 5 )

rSNPs within LD-proxies of this variant (count:96)

rs_ID	r²[population]
rs10131155	0.92[ASN][1000 genomes]
rs10131416	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs10132424	0.83[AFR][1000 genomes];0.88[ASN][1000 genomes]
rs10132969	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs10133243	0.96[AFR][1000 genomes];0.91[ASN][1000 genomes]
rs10133411	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs10133696	0.91[AFR][1000 genomes];0.95[AMR][1000 genomes];1.00[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs10133848	0.92[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs10134530	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs10136732	0.83[AFR][1000 genomes];0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs10138256	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs10142835	0.90[ASN][1000 genomes]
rs10142879	0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs10143170	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs10143839	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs10145001	0.82[AMR][1000 genomes];0.89[EUR][1000 genomes]
rs10145005	0.86[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs10145013	0.89[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs10147522	0.81[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs10149286	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs10150781	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs10873173	0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11158542	0.89[EUR][1000 genomes]
rs11158543	0.95[AMR][1000 genomes];0.99[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs11158544	0.90[ASN][1000 genomes]
rs11623457	0.97[AMR][1000 genomes];0.99[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs11625265	0.96[AFR][1000 genomes];0.98[AMR][1000 genomes];0.95[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11626222	0.92[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs11627387	0.81[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs11628221	0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11845653	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs11847054	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs11848179	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11849935	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs11851236	0.84[AMR][1000 genomes];0.90[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs12050238	0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12050358	0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12385910	0.89[ASN][1000 genomes]
rs12385918	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs12586212	0.96[AFR][1000 genomes];0.92[ASN][1000 genomes]
rs12588886	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs12589947	0.96[AFR][1000 genomes];0.91[ASN][1000 genomes]
rs1453004	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs1453007	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs1453009	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs1470851	1.00[AFR][1000 genomes];0.97[AMR][1000 genomes];0.99[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs17101896	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs1980519	0.97[AMR][1000 genomes];0.98[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs1980520	0.97[AMR][1000 genomes];0.98[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs1982440	0.87[AFR][1000 genomes];0.92[ASN][1000 genomes]
rs2045024	0.92[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs2123459	0.90[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs2123460	0.89[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs2198347	0.91[AFR][1000 genomes];0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2281603	0.83[AFR][1000 genomes]
rs28446048	0.96[AFR][1000 genomes];0.92[ASN][1000 genomes]
rs28469649	1.00[AFR][1000 genomes];0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs28626711	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs28666045	0.93[AMR][1000 genomes];0.98[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs28730549	0.85[AMR][1000 genomes];0.90[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs28738919	0.97[AMR][1000 genomes];0.99[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs28766386	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs28827477	0.89[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs35115595	0.92[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs35451957	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs3742606	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs3742608	0.92[AMR][1000 genomes];0.96[EUR][1000 genomes]
rs3783722	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs3783723	0.96[AFR][1000 genomes];0.92[ASN][1000 genomes]
rs3783724	0.96[AFR][1000 genomes];0.92[ASN][1000 genomes]
rs3783727	0.83[EUR][1000 genomes]
rs4632045	0.97[AMR][1000 genomes];0.99[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs57525201	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs58893738	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs59213791	0.87[AFR][1000 genomes];0.89[ASN][1000 genomes]
rs59440409	0.96[AFR][1000 genomes];0.91[ASN][1000 genomes]
rs59512674	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs59577187	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs60908674	0.96[AFR][1000 genomes];0.91[ASN][1000 genomes]
rs61615397	0.96[AFR][1000 genomes];0.91[ASN][1000 genomes]
rs61985663	0.92[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs61985668	0.95[AMR][1000 genomes];0.99[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs61985706	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs61985707	0.96[AFR][1000 genomes];0.92[ASN][1000 genomes]
rs61985711	0.87[AFR][1000 genomes];0.90[ASN][1000 genomes]
rs6573559	0.86[AMR][1000 genomes];0.95[EUR][1000 genomes]
rs7160634	0.89[AMR][1000 genomes];0.86[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs73265639	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs73265640	0.92[AMR][1000 genomes];0.99[EUR][1000 genomes]
rs73265641	0.92[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs73267743	0.96[AFR][1000 genomes];0.92[ASN][1000 genomes]
rs73267744	0.96[AFR][1000 genomes];0.92[ASN][1000 genomes]
rs745686	0.84[EUR][1000 genomes]
rs926803	0.89[AMR][1000 genomes];0.91[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs9323451	0.95[AMR][1000 genomes];0.97[EUR][1000 genomes]
rs9323452	1.00[AFR][1000 genomes];0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:1 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv521823	chr14:64969342-64995694	Enhancers Weak transcription Active TSS Flanking Active TSS Genic enhancers Strong transcription Transcr. at gene 5' and 3' Bivalent Enhancer ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	56 gene(s)	inside rSNPs	diseases

mRNA abundance (count:5)

SNP	Gene	Cis/trans	Tissue	Source
rs1966865	ZBTB25	cis	Nerve Tibial	GTEx
rs1966865	ZBTB25	cis	lung	GTEx
rs1966865	ZBTB1	Cis_1M	lymphoblastoid	RTeQTL
rs1966865	ZBTB25	Cis_1M	lymphoblastoid	RTeQTL
rs1966865	ZBTB25	cis	multi-tissue	Pritchard

Chromatin state (count:123 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr14:64972800-64976200	Enhancers	Sigmoid Colon	Sigmoid Colon
2	chr14:64972800-64976400	Enhancers	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
3	chr14:64972800-64977000	Weak transcription	Brain Dorsolateral Prefrontal Cortex	brain
4	chr14:64972800-64978800	Enhancers	Primary monocytes fromperipheralblood	blood
5	chr14:64972800-64979200	Enhancers	Small Intestine	intestine
6	chr14:64972800-64988400	Weak transcription	H9 Cell Line	embryonic stem cell
7	chr14:64972800-64991600	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
8	chr14:64973000-64976000	Enhancers	Fetal Adrenal Gland	Adrenal Gland
9	chr14:64973000-64976400	Enhancers	Primary hematopoietic stem cells	blood
10	chr14:64973000-64979400	Enhancers	Primary B cells from peripheral blood	blood
11	chr14:64973200-64976000	Enhancers	HUES64 Cell Line	embryonic stem cell
12	chr14:64973200-64976000	Enhancers	iPS-18 Cell Line	embryonic stem cell
13	chr14:64973200-64976200	Flanking Active TSS	Primary T helper cells PMA-I stimulated	--
14	chr14:64973200-64987800	Weak transcription	Fetal Muscle Trunk	muscle
15	chr14:64973400-64976000	Flanking Active TSS	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
16	chr14:64973400-64976200	Enhancers	Primary Natural Killer cells fromperipheralblood	blood
17	chr14:64973400-64976200	Enhancers	Stomach Mucosa	stomach
18	chr14:64973600-64976000	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
19	chr14:64973600-64976000	Enhancers	Rectal Mucosa Donor 31	rectum
20	chr14:64973600-64976200	Enhancers	HUES6 Cell Line	embryonic stem cell
21	chr14:64973600-64976200	Enhancers	Brain Hippocampus Middle	brain
22	chr14:64973600-64976400	Enhancers	Skeletal Muscle Female	skeletal muscle
23	chr14:64973800-64976000	Enhancers	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
24	chr14:64973800-64976000	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
25	chr14:64973800-64976000	Enhancers	Ganglion Eminence derived primary cultured neurospheres	brain
26	chr14:64973800-64976000	Enhancers	Foreskin Melanocyte Primary Cells skin03	Skin
27	chr14:64973800-64976000	Enhancers	Liver	Liver
28	chr14:64973800-64976000	Enhancers	Brain Germinal Matrix	brain
29	chr14:64973800-64976200	Enhancers	HUES48 Cell Line	embryonic stem cell
30	chr14:64973800-64976200	Enhancers	Colonic Mucosa	Colon
31	chr14:64973800-64976200	Enhancers	Fetal Thymus	thymus
32	chr14:64973800-64976200	Enhancers	Right Atrium	heart
33	chr14:64973800-64977200	Weak transcription	Fetal Kidney	kidney
34	chr14:64973800-64977600	Weak transcription	Primary neutrophils fromperipheralblood	blood
35	chr14:64973800-64978000	Enhancers	Skeletal Muscle Male	skeletal muscle
36	chr14:64973800-64978400	Enhancers	HepG2	liver
37	chr14:64973800-64979400	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Female	--
38	chr14:64973800-64980000	Enhancers	Primary T killer naive cells fromperipheralblood	blood
39	chr14:64974000-64984400	Enhancers	Primary T helper naive cells fromperipheralblood	blood
40	chr14:64974200-64976000	Enhancers	Foreskin Melanocyte Primary Cells skin01	Skin
41	chr14:64974200-64976200	Enhancers	Right Ventricle	heart
42	chr14:64974200-64979400	Enhancers	Primary B cells from cord blood	blood
43	chr14:64974400-64976200	Enhancers	iPS-20b Cell Line	embryonic stem cell
44	chr14:64974400-64977400	Weak transcription	Brain Cingulate Gyrus	brain
45	chr14:64974400-64977800	Weak transcription	Fetal Lung	lung
46	chr14:64974400-64978000	Weak transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
47	chr14:64974400-64988200	Weak transcription	H9 Derived Neuron Cultured Cells	ES cell derived
48	chr14:64974400-64988400	Weak transcription	Stomach Smooth Muscle	stomach
49	chr14:64974600-64976200	Genic enhancers	Thymus	Thymus
50	chr14:64974600-64976400	Enhancers	HMEC	breast

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links